An evaluation of cognitive-behaviour therapy for depression in patients with multiple sclerosis
Abstract
Twenty depressed multiple sclerotic patients were randomly allocated either to cognitive-behaviour therapy or to a waiting list control condition. Assessment of depressive symptoms was conducted at pre-treatment, post-treatment, and a four-week follow-up. In comparison to the waiting list condition, cognitive-behaviour therapy was found to result in clinically and statistically significant improvement on most measures. Although the mechanism by which such treatment achieves its effects is unclear, these results clearly support the use of cognitive-behavioural treatments for depression in this population.
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One trial (Larcombe and Wilson, 1984) was an outlier, with an estimate five times as large as the others.
“One trial was an outlier, with an estimate five times as large as the others (Larcombe and Wilson, 1984”
From Systematic review and meta-analysis of interventions for depression and anxiety in persons with multiple sclerosis (2016) · cites this paper as Larcombe and Wilson, 1984
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References 30 · Cited by 118
- Authors
- Larcombe, N. A., & Wilson, P. H.
- Affiliations
- The University of Sydney (AU)
- Corresponding author
- Wilson, Peter H.
- ORCID
- Wilson, Peter H.
- Venue
- British Journal of Psychiatry
- Publisher
- Royal College of Psychiatrists
- Published
- 1984-10
- Volume
- 145
- Issue
- 4
- Pages
- 366-371
- ISSN
- 0007-1250 (ISSN-L)
- 1472-1465
- OpenAlex
- W1998332655
- Cited by
- 118
- References
- 30
- Citations by year
- 2025: 2 · 2024: 2 · 2021: 1 · 2020: 2 · 2019: 1 · 2018: 2 · 2017: 3 · 2016: 4 · 2015: 3 · 2014: 1 · 2013: 7 · 2012: 2
- FWCI
- 2.21
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- The British Journal of Psychiatry (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Multiple Sclerosis Society
- Topics
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Health Sciences › Medicine › Pathology and Forensic Medicine › Multiple Sclerosis Research Studies
- Social Sciences › Psychology › Clinical Psychology › Psychological Treatments and Assessments
- Keywords
- cognitive behavioral therapy, depression, multiple sclerosis, treatment efficacy, waitlist control, depressive symptoms, psychotherapy
- MeSH terms
- Adult, Behavior Therapy, Cognition Disorders, Depressive Disorder, Female, Humans, Male, Middle Aged, Multiple Sclerosis, Psychiatric Status Rating Scales
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