Anorexia nervosa: a study of 34 twin pairs and one set of triplets
Abstract
In a collaborative study between St George's and the Maudsley Hospitals, 34 pairs of twins and one set of triplets were identified in which the proband had anorexia nervosa. The diagnosis was based on standard criteria and zygosity was established by blood group analysis or by use of the physical resemblance questionnaire. In the 30 female twin pairs, 9/16 of the monozygotic (MZ) and 1/14 of the dizygotic (DZ) pairs were concordant for anorexia nervosa. Three of the non-anorexia co-twins had other psychiatric illnesses, and two had minor eating disorders. None of the male co-twins had anorexia nervosa.
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References 47 · Cited by 174
- Authors
- Holland, A. J., Hall, A., Murray, R., Russell, G. F. M., & Crisp, A. H.
- Affiliations
- Maudsley Hospital (GB)
- St George's Hospital (GB)
- Bethlem Royal Hospital (GB)
- St George's, University of London (GB)
- Corresponding author
- Holland, A. J.
- Venue
- British Journal of Psychiatry
- Publisher
- Royal College of Psychiatrists
- Published
- 1984-10
- Volume
- 145
- Issue
- 4
- Pages
- 414-419
- ISSN
- 0007-1250 (ISSN-L)
- 1472-1465
- OpenAlex
- W1970231845
- Cited by
- 174
- References
- 47
- Citations by year
- 2026: 3 · 2025: 2 · 2024: 4 · 2022: 1 · 2021: 2 · 2020: 1 · 2019: 4 · 2014: 3 · 2013: 2 · 2012: 1
- FWCI
- 8.55
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- The British Journal of Psychiatry (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Social Sciences › Psychology › Clinical Psychology › Eating Disorders and Behaviors
- Health Sciences › Nursing › Nutrition and Dietetics › Nutrition, Health and Food Behavior
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Genetic Associations and Epidemiology
- Keywords
- anorexia nervosa, twin concordance, monozygotic twins, dizygotic twins, zygosity, heritability, eating disorders, sex differences
- MeSH terms
- Adult, Anorexia Nervosa, Feeding and Eating Disorders, Mental Disorders, Diseases in Twins, Female, Humans, Male, Pregnancy, Triplets, Twins, Dizygotic, Twins, Monozygotic
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