The DOI matches its Crossref record.
Induction of Mania with Selective Serotonin Re-uptake Inhibitors and Tricyclic Antidepressants
Abstract
The rate of treatment-emergent switch into mania has been calculated from all available clinical trial data on the selective serotonin re-uptake inhibitors (SSRIs) fluoxetine, fluvoxamine, paroxetine, and sertraline, relative to comparative groups treated with tricyclic antidepressants (TCAs) or placebo. In predominantly unipolar depressives, the rate of manic switch is less than 1% and differences between drugs and placebo are statistically but not clinically significant. In bipolar depressives, manic switch occurs substantially more often with TCAs (11.2%) than with SSRIs (3.7%) or placebo (4.2%).
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Citations
Cited by
Yatham, L. N., Kennedy, S. H., Parikh, S. V., Schaffer, A., Bond, D. J., Frey, B. N., Sharma, V., Goldstein, B. I., Rej, S., Beaulieu, S., et al. (2018) · Bipolar Disorders · doi:10.1111/bdi.12609 · Cited by 1,852
Goodwin, G., Haddad, P., Ferrier, I., Aronson, J., Barnes, T., Cipriani, A., Coghill, D., Fazel, S., Geddes, Jr., Grunze, H., et al. (2016) · Journal of Psychopharmacology · doi:10.1177/0269881116636545 · Cited by 1,309
Tohen, M., Vieta, E., Calabrese, J., Ketter, T. A., Sachs, G., Bowden, C., Mitchell, P. B., Centorrino, F., Risser, R., Baker, R. W., et al. (2003) · Archives of General Psychiatry · doi:10.1001/archpsyc.60.11.1079 · Cited by 908
Akiskal, H. S., Bourgeois, M. L., Angst, J., Post, R., Möller, H.-J., & Hirschfeld, R. (2000) · Journal of Affective Disorders · doi:10.1016/s0165-0327(00)00203-2 · Cited by 874
Malhi, G. S., Bassett, D., Boyce, P., Bryant, R., Fitzgerald, P. B., Fritz, K., Hopwood, M., Lyndon, B., Mulder, R., Murray, G., et al. (2015) · Australian & New Zealand Journal of Psychiatry · doi:10.1177/0004867415617657 · Cited by 842
“CBR Australian & New Zealand Journal of Psychiatry, 49(12) (Gijsman et al., 2004; Leverich et al., 2006; Nemeroff et al., 2001; Peet, 1994; Post et al., 2006; Sachs et al., 1994; Vieta et al., 2002).”
Background
Metadata
- Authors
- Peet, M.
- Venue
- British Journal of Psychiatry
- Publisher
- Royal College of Psychiatrists
- Published
- 1994-04
- Volume
- 164
- Issue
- 4
- Pages
- 549-550
- ISSN
- 0007-1250 (ISSN-L)
- 1472-1465
- OpenAlex
- W2084686735
- Cited by
- 474
- References
- 0
- FWCI
- 10.74
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: Induction of Mania with Selective Serotonin Re-uptake Inhibitors and Tricyclic Antidepressants. https://app.cochat.ai/papers/10.1192/bjp.164.4.549
- The paper
- Peet, M. (1994). Induction of Mania with Selective Serotonin Re-uptake Inhibitors and Tricyclic Antidepressants. British Journal of Psychiatry. https://doi.org/10.1192/bjp.164.4.549
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
