Recurrence in affective disorder: I. Case register study
Abstract
Background In recent years, studies of the risk of recurrence in affective disorder in relation to the number of prior episodes have given contradictory results. Method Survival analysis was used to calculate the rate of recurrence after successive episodes in a case register study including all hospital admissions with primary affective disorder in Denmark during 1971-1993. A total of 20,350 first-admission patients were discharged with a diagnosis of affective disorder, depressive or manic/cyclic type. Results The rate of recurrence increased with the number of previous episodes in both unipolar and bipolar disorder. Initially, the two types of disorders followed markedly different courses, but later in the course of the illness the rate of recurrence was the same for the two disorders. Conclusions The course of severe unipolar and bipolar disorder seems to be progressive in nature despite the effect of treatment.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Several studies of the long-term course of MDD show that recurrence rates stabilise only after many years, such as 2.5 years, 10 years, or about 15 years.
“In particular, several studies of the long-term course of MDD show that recurrence rates stabilise only after many years, such as 2.5 years (Solomon et al. 2000), 10 years (Mattisson et al. 2007) or about 15 years (Kessing et al. 1998).”
From Empirical evidence for definitions of episode, remission, recovery, relapse and recurrence in depression: a systematic review (2019) · cites this paper as Kessing et al. 1998
No citation lists for this paper
No citation lists for this paper yet — checked again daily.
Cited by 214
- Authors
- Kessing, L. V., Bolwig, T. G., Andersen, P. K., & Mortensen, P. B.
- Affiliations
- University of Copenhagen (DK)
- Aarhus University (DK)
- Corresponding author
- Kessing, Lars Vedel
- Venue
- British Journal of Psychiatry
- Publisher
- Royal College of Psychiatrists
- Published
- 1998-01
- Volume
- 172
- Issue
- 1
- Pages
- 23-28
- ISSN
- 0007-1250 (ISSN-L)
- 1472-1465
- OpenAlex
- W1989602692
- Cited by
- 214
- References
- 0
- Citations by year
- 2025: 1 · 2024: 5 · 2022: 5 · 2021: 3 · 2019: 5 · 2018: 5 · 2017: 5 · 2016: 9 · 2015: 8 · 2014: 3 · 2013: 7 · 2012: 6
- FWCI
- 12.73
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- The British Journal of Psychiatry (publishedVersion)
- PubMed (publishedVersion)
- Research at the University of Copenhagen (University of Copenhagen) (submittedVersion)
- Funders
- National Institutes of Health
- National Institute of Mental Health
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Bipolar Disorder and Treatment
- Health Sciences › Medicine › Pharmacology › Treatment of Major Depression
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Mental Health Research Topics
- Keywords
- mood disorders, recurrence, major depressive disorder, bipolar disorder, clinical course, disease progression, hospitalization
- MeSH terms
- Adult, Bipolar Disorder, Denmark, Depressive Disorder, Female, Hospitalization, Humans, Male, Middle Aged, Recurrence, Risk Factors, Sex Factors, Time Factors, Survival Rate, Survival Analysis, Mood Disorders
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
