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Assessing effectiveness of treatment of depression in primary care: Partially randomised preference trial

Open access
Bedi, Navjot, Chilvers, Clair, Churchill, Richard, Dewey, Michael, Duggan, Conor, Fielding, Katherine, Gretton, Virginia, Miller, Paul, Harrison, Glynn, Lee, Alan, Williams, Idris·2000·British Journal of Psychiatry

Abstract

Background: There is a mismatch between the wish of a patient with depression to have counselling and the prescription of antidepressants by the doctor. Aims: To determine whether counselling is as effective as antidepressants for depression in primary care and whether allowing patients to choose their treatment affects their response. Method: A partially randomised preference trial, with patients randomised to either antidepressants or counselling or given their choice of either treatment. The treatment and follow-up were identical in the randomised and patient preference arms. Results: There were 103 randomised and 220 preference patients in the trial. We found: no differences in the baseline characteristics of the randomised and preference groups; that the two treatments were equally effective at 8 weeks, both for the randomised group and when the randomised and patient preference groups for a particular treatment were combined; and that expressing a preference for either treatment conferred no additional benefit on outcome. Conclusions: These data challenge several assumptions about the most appropriate treatment for depression in a primary care setting.

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Crossref · 10.1192/bjp.177.4.312

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Metadata

Authors
Bedi, N., Chilvers, C., Churchill, R., Dewey, M., Duggan, C., Fielding, K., Gretton, V., Miller, P., Harrison, G., Lee, A., & Williams, I.
Venue
British Journal of Psychiatry
Published
2000-10
Volume
177
Issue
4
Pages
312-318
ISSN
  • 0007-1250 (ISSN-L)
  • 1472-1465
OpenAlex
W2113921657
Cited by
193
References
4
FWCI
13.60
Type
journal article
Language
en
Open access
bronze

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CoChat. (2026). Citation check: Assessing effectiveness of treatment of depression in primary care: Partially randomised preference trial. https://app.cochat.ai/papers/10.1192/bjp.177.4.312
The paper
Bedi, N., Chilvers, C., Churchill, R., Dewey, M., Duggan, C., Fielding, K., Gretton, V., Miller, P., Harrison, G., Lee, A., & Williams, I. (2000). Assessing effectiveness of treatment of depression in primary care: Partially randomised preference trial. British Journal of Psychiatry. https://doi.org/10.1192/bjp.177.4.312

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.