Adolescent brain development and animal models
Abstract
Research examining brain development during adolescence is escalating rapidly along multiple dimensions, as illustrated by the remarkable diversity of trans-disciplinary work shown in this symposium. Ontogenetic transitions characteristics of adolescence are common among mammalian species. Although no other species demonstrates the full complexity of brain and behavioral function seen in human adolescents, adolescence appears to be a highly conserved developmental stage, its characteristics sculpted to meet common evolutionary pressures that include the avoidance of inbreeding at this time of sexual emergence. Numerous similarities are found between human adolescents and adolescents of other species in terms of developmental history and genetic constraints, as well as neurobehavioral and physiological characteristics. These similarities provide face and construct validity to support use of animal models as tools for the study of adolescence and the unique opportunities and vulnerabilities afforded by this developmental transition.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
The developmental mechanisms that account for major remodeling of connectivity occur before the onset of adolescence, i.e., before postnatal day 28 (PD28) in rodents, 9 months in cats, and 3 years in non-human primates.
“The developmental mechanisms that account for major remodeling of connectivity occur before the onset of adolescence, i.e., before postnatal day 28 (PD28) in rodents, 9 months in cats, and 3 years in non-human primates15, 16, 17”
From A role for synaptic plasticity in the adolescent development of executive function (2013) · cites this paper as [15]
Measures of exploration and novelty seeking in both humans and rodents increase during adolescence.
“Measures of exploration and novelty seeking in both humans and rodents increase during adolescence (Spear, 2004; Steinberg et al., 2008).”
From Does puberty mark a transition in sensitive periods for plasticity in the associative neocortex? (2017) · cites this paper as Spear, 2004
The citation lists haven’t been fetched yet
References 13 · Cited by 215
- Authors
- SPEAR, L. P.
- Affiliations
- Binghamton University (US)
- Corresponding author
- SPEAR, LINDA PATIA
- ORCID
- SPEAR, LINDA PATIA
- Venue
- Annals of the New York Academy of Sciences
- Publisher
- Wiley
- Published
- 2004-06
- Volume
- 1021
- Issue
- 1
- Pages
- 23-26
- ISSN
- 0077-8923 (ISSN-L)
- 1749-6632
- OpenAlex
- W2076985921
- Cited by
- 215
- References
- 13
- Citations by year
- 2025: 7 · 2024: 14 · 2023: 8 · 2022: 7 · 2021: 10 · 2020: 9 · 2019: 5 · 2018: 6 · 2017: 16 · 2016: 18 · 2015: 6 · 2014: 12 · 2013: 17 · 2012: 13
- FWCI
- 3.19
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Annals of the New York Academy of Sciences (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Neuroscience › Cognitive Neuroscience › Neural and Behavioral Psychology Studies
- Social Sciences › Psychology › Social Psychology › Neuroendocrine regulation and behavior
- Health Sciences › Medicine › Reproductive Medicine › Hypothalamic control of reproductive hormones
- Keywords
- adolescent brain development, ontogeny, evolutionary conservation, sexual maturation, neurobehavioral development, developmental vulnerability, cross-species comparison
- MeSH terms
- Adolescent, Animals, Brain, Humans, Puberty, Models, Animal
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
