The DOI matches its Crossref record; 84 of the 84 references it cites were found in a registry or an index.
Older Female Cancer Patients: Importance, Causes, and Consequences of Undertreatment
Abstract
Despite increased interest in treatment of senior cancer patients, older patients are much too often undertreated. This review aims to present data on treatment practices of older women with breast and gynecologic cancers and on the consequences of undertreatment on patient outcome. We also discuss the reasons and validity of suboptimal care in older patients. Numerous studies have reported suboptimal treatment in older breast and gynecologic cancer patients. Undertreatment displays multiple aspects: from lowered doses of adjuvant chemotherapy to total therapeutic abstention. Undertreatment also concerns palliative care, treatment of pain, and reconstruction. Only few studies have evaluated the consequences of nonstandard approaches on cancer-specific mortality, taking into account other prognostic factors and comorbidities. These studies clearly showed that undertreatment increased disease-specific mortality for breast and ovarian cancers. For other gynecological cancers, data were insufficient to draw conclusions. Objective reasons at the origin of undertreatment were, notably, higher prevalence of comorbidity, lowered life expectancy, absence of data on treatment efficacy in clinical trials, and increased adverse effects of treatment. More subjective reasons were putative lowered benefits of treatment, less aggressive cancers, social marginalization, and physician's beliefs. Undertreatment in older cancer patients is a well-documented phenomenon responsible for preventable cancer deaths. Treatments are still influenced by unclear standards and have to be adapted to the older patient's general health status, but should also offer the best chance of cure.
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Fisher, B., Costantino, J. P., Wickerham, D. L., Redmond, C. K., Kavanah, M., Cronin, W. M., Vogel, V., Robidoux, A., Dimitrov, N., Atkins, J., et al. (1998) · JNCI: Journal of the National Cancer Institute · doi:10.1093/jnci/90.18.1371 · Cited by 5,485
Bristow, R. E., Tomacruz, R. S., Armstrong, D. K., Trimble, E. L., & Montz, F. J. (2002) · Journal of Clinical Oncology · doi:10.1200/jco.2002.20.5.1248 · Cited by 2,312
Creutzberg, C. L., van Putten, W. L., Koper, P. C., Lybeert, M. L., Jobsen, J. J., Wárlám-Rodenhuis, C. C., De Winter, K. A., Lutgens, L. C., van den Bergh, A. C., van de Steen-Banasik, E., et al. (2000) · The Lancet · doi:10.1016/s0140-6736(00)02139-5 · Cited by 1,773
Citron, M. L., Berry, D. A., Cirrincione, C., Hudis, C., Winer, E. P., Gradishar, W. J., Davidson, N. E., Martino, S., Livingston, R., Ingle, J. N., et al. (2003) · Journal of Clinical Oncology · doi:10.1200/jco.2003.09.081 · Cited by 1,564
Use of comprehensive geriatric assessment in older cancer patients:
Extermann, M., Aapro, M., Bernabei, R., Cohen, H. J., Droz, J.-P., Lichtman, S., Mor, V., Monfardini, S., Repetto, L., Sørbye, L., et al. (2005) · Critical Reviews in Oncology/Hematology · doi:10.1016/j.critrevonc.2005.06.003 · Cited by 1,098
Participation of Patients 65 Years of Age or Older in Cancer Clinical Trials
Lewis, J. H., Kilgore, M. L., Goldman, D. P., Trimble, E. L., Kaplan, R., Montello, M. J., Housman, M. G., & Escarce, J. J. (2003) · Journal of Clinical Oncology · doi:10.1200/jco.2003.08.010 · Cited by 1,031
Comorbidity and functional status are independent in older cancer patients.
Extermann, M., Overcash, J., Lyman, G. H., Parr, J., & Balducci, L. (1998) · Journal of Clinical Oncology · doi:10.1200/jco.1998.16.4.1582 · Cited by 984
Repetto, L., Fratino, L., Audisio, R. A., Venturino, A., Gianni, W., Vercelli, M., Parodi, S., Lago, D. D., Gioia, F., Monfardini, S., et al. (2002) · Journal of Clinical Oncology · doi:10.1200/jco.20.2.494 · Cited by 912
Effect of Age and Comorbidity in Postmenopausal Breast Cancer Patients Aged 55 Years and Older
Yancik, R. (2001) · JAMA · doi:10.1001/jama.285.7.885 · Cited by 896
Cited by
Puts, M. T. E., Papoutsis, A., Springall, E., & Tourangeau, A. E. (2012) · Supportive Care in Cancer · doi:10.1007/s00520-012-1450-7 · Cited by 224
Ellis, J., Lin, J., Walsh, A., Lo, C., Shepherd, F. A., Moore, M., Li, M., Gagliese, L., Zimmermann, C., & Rodin, G. (2009) · Journal of Clinical Oncology · doi:10.1200/jco.2007.15.4864 · Cited by 128
How to Implement a Geriatric Assessment in Your Clinical Practice
Sattar, S., Alibhai, S. M. H., Wildiers, H., & Puts, M. T. E. (2014) · The Oncologist · doi:10.1634/theoncologist.2014-0180 · Cited by 75
Metadata
- Authors
- Bouchardy, C., Rapiti, E., Blagojevic, S., Vlastos, A.-T., & Vlastos, G.
- Venue
- Journal of Clinical Oncology
- Published
- 2007-05-10
- Volume
- 25
- Issue
- 14
- Pages
- 1858-1869
- ISSN
- 0732-183X (ISSN-L)
- 1527-7755
- OpenAlex
- W2069103088
- Cited by
- 306
- References
- 84
- FWCI
- 7.54
- Type
- journal article
- Language
- en
- Open access
- closed
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- Bouchardy, C., Rapiti, E., Blagojevic, S., Vlastos, A.-T., & Vlastos, G. (2007). Older Female Cancer Patients: Importance, Causes, and Consequences of Undertreatment. Journal of Clinical Oncology. https://doi.org/10.1200/jco.2006.10.4208
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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