Student or educator? Sign up with your school email and get 6 months of Pro free.
Cited by 414

The DOI matches its Crossref record; 66 of the 66 references it cites were found in a registry or an index.

Renal Impairment in Patients With Multiple Myeloma: A Consensus Statement on Behalf of the International Myeloma Working Group

Dimopoulos, Meletios A., Terpos, Evangelos, Chanan-Khan, Asher, Leung, Nelson, Ludwig, Heinz, Jagannath, Sundar, Niesvizky, Ruben, Giralt, Sergio, Fermand, Jean-Paul, Bladé, Joan, Comenzo, Raymond L., Sezer, Orhan, Palumbo, Antonio, Harousseau, Jean-Luc, Richardson, Paul G., Barlogie, Bart, Anderson, Kenneth C., Sonneveld, Pieter, Tosi, Patrizia, Cavo, Michele, Rajkumar, S. Vincent, Durie, Brian G.M., San Miguel, Jésus·2010·Journal of Clinical Oncology

Abstract

Renal impairment is a common complication of multiple myeloma (MM). The estimated glomerular filtration rate (eGFR) using the Modification of Diet in Renal Disease formula is the recommended method for the assessment of renal function in patients with MM with stabilized serum creatinine. In acute renal injury, the RIFLE (risk, injury, failure, loss and end-stage kidney disease) and Acute Renal Injury Network criteria seem to be appropriate to define the severity of renal impairment. Novel criteria based on eGFR measurements are recommended for the definition of the reversibility of renal impairment. Rapid intervention to reverse renal dysfunction is critical for the management of these patients, especially for those with light chain cast nephropathy. Bortezomib with high-dose dexamethasone is considered as the treatment of choice for such patients. There is limited experience with thalidomide in patients with myeloma with renal impairment. Thus, thalidomide can be carefully administered, mainly in the context of well-designed clinical trials, to evaluate if it can improve the rapidity and probability of response that is produced by the combination with bortezomib and high-dose dexamethasone. Lenalidomide is effective in this setting and can reverse renal insufficiency in a significant subset of patients, when it is given at reduced doses, according to renal function. The role of plasma exchange in patients with suspected light chain cast nephropathy and renal impairment is controversial. High-dose melphalan (140 mg/m 2) and autologous stem-cell transplantation should be limited to younger patients with chemosensitive disease.

Overview

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Integrity signals

Registry

Crossref · 10.1200/jco.2010.30.8791

Cites

66 of 66 references verified0 citation errors · 0 not checkable

Statistics

Verification

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Citations

Cites

Show all 66 references

Cited by

See all 414

Metadata

Authors
Dimopoulos, M. A., Terpos, E., Chanan-Khan, A., Leung, N., Ludwig, H., Jagannath, S., Niesvizky, R., Giralt, S., Fermand, J.-P., Bladé, J., Comenzo, R. L., Sezer, O., Palumbo, A., Harousseau, J.-L., Richardson, P. G., Barlogie, B., Anderson, K. C., Sonneveld, P., Tosi, P., Cavo, M., Rajkumar, S. V., Durie, B. G. M., & San Miguel, J.
Venue
Journal of Clinical Oncology
Published
2010-11-20
Volume
28
Issue
33
Pages
4976-4984
ISSN
  • 0732-183X (ISSN-L)
  • 1527-7755
OpenAlex
W1998723844
Cited by
414
References
66
FWCI
20.83
Type
journal article
Language
en
Open access
closed

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

How to cite

Cite CoChat for the checks on this page, and the paper for its own findings.

This page
CoChat. (2026). Citation check: Renal Impairment in Patients With Multiple Myeloma: A Consensus Statement on Behalf of the International Myeloma Working Group. https://app.cochat.ai/papers/10.1200/jco.2010.30.8791
The paper
Dimopoulos, M. A., Terpos, E., Chanan-Khan, A., Leung, N., Ludwig, H., Jagannath, S., Niesvizky, R., Giralt, S., Fermand, J.-P., Bladé, J., Comenzo, R. L., Sezer, O., Palumbo, A., Harousseau, J.-L., Richardson, P. G., Barlogie, B., Anderson, K. C., Sonneveld, P., Tosi, P., . . . San Miguel, J. (2010). Renal Impairment in Patients With Multiple Myeloma: A Consensus Statement on Behalf of the International Myeloma Working Group. Journal of Clinical Oncology. https://doi.org/10.1200/jco.2010.30.8791

Data sources

Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.