Germline testing for individuals with pancreatic cancer: the benefits and challenges to casting a wider net
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Identifying germline pathogenic variants can facilitate cancer prevention and increase early detection through enhanced surveillance and risk-reducing interventions in individuals harboring such variants.
“The rationale is that identifying germline pathogenic variants can facilitate cancer prevention and increase early detection through enhanced surveillance and risk-reducing interventions in individuals harboring such variants.190”
From Artificial Intelligence and Early Detection of Pancreatic Cancer: 2020 Summative Review (2021) · cites this paper as [190]
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References 30 · Cited by 14
- Authors
- Yurgelun, M. B.
- Affiliations
- Brigham and Women's Hospital (US)
- Corresponding author
- Yurgelun, Matthew B.
- ORCID
- Yurgelun, Matthew B.
- Venue
- Journal of Clinical Oncology
- Published
- 2017-10-20
- Volume
- 35
- Issue
- 30
- Pages
- 3375-3377
- ISSN
- 0732-183X (ISSN-L)
- 1527-7755
- OpenAlex
- W2745693097
- Cited by
- 14
- References
- 30
- Citations by year
- 2025: 1 · 2024: 1 · 2023: 2 · 2021: 3 · 2019: 1 · 2018: 6
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Clinical Oncology (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Cancer Institute (P50CA127003)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › BRCA gene mutations in cancer
- Health Sciences › Medicine › Oncology › Pancreatic and Hepatic Oncology Research
- Health Sciences › Medicine › Pathology and Forensic Medicine › Genetic factors in colorectal cancer
- Keywords
- germline genetic testing, pancreatic cancer, hereditary cancer predisposition, genetic testing, germline mutations
- MeSH terms
- Adenocarcinoma, Germ Cells, Humans, Pancreatic Neoplasms, Germ-Line Mutation, Carcinoma, Pancreatic Ductal
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