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Cited by 304

The DOI matches its Crossref record; 88 of the 88 references it cites were found in a registry or an index.

Use of Opioids for Adults With Pain From Cancer or Cancer Treatment: ASCO Guideline

Paice, Judith A., Bohlke, Kari, Barton, Debra, Craig, David S., El-Jawahri, Areej, Hershman, Dawn L., Kong, Lynn R., Kurita, Geana P., LeBlanc, Thomas W., Mercadante, Sebastiano, Novick, Kristina L. M., Sedhom, Ramy, Seigel, Carole, Stimmel, Joanna, Bruera, Eduardo·2023·Journal of Clinical Oncology
DOI 10.1200/jco.22.02198
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Abstract

PURPOSE: To provide guidance on the use of opioids to manage pain from cancer or cancer treatment in adults. METHODS: A systematic review of the literature identified systematic reviews and randomized controlled trials of the efficacy and safety of opioid analgesics in people with cancer, approaches to opioid initiation and titration, and the prevention and management of opioid adverse events. PubMed and the Cochrane Library were searched from January 1, 2010, to February 17, 2022. American Society of Clinical Oncology convened an Expert Panel to review the evidence and formulate recommendations. RESULTS: The evidence base consisted of 31 systematic reviews and 16 randomized controlled trials. Opioids have primarily been evaluated in patients with moderate-to-severe cancer pain, and they effectively reduce pain in this population, with well-characterized adverse effects. Evidence was limited for several of the questions of interest, and the Expert Panel relied on consensus for these recommendations or noted that no recommendation could be made at this time. RECOMMENDATIONS: Opioids should be offered to patients with moderate-to-severe pain related to cancer or active cancer treatment unless contraindicated. Opioids should be initiated PRN (as needed) at the lowest possible dose to achieve acceptable analgesia and patient goals, with early assessment and frequent titration. For patients with a substance use disorder, clinicians should collaborate with a palliative care, pain, and/or substance use disorder specialist to determine the optimal approach to pain management. Opioid adverse effects should be monitored, and strategies are provided for prevention and management. Additional information is available at www.asco.org/supportive-care-guidelines .

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Citations

Cites

Show all 88 references

Research works printed but not linked: 49

  1. World Health Organization, 2018, WHO Guidelines for the Pharmacological and Radiotherapeutic Management of Cancer Pain in Adults and Adolescents
  2. Candy B, 2018, Cochrane Database Syst Rev, 6, CD006332
  3. 10.1177/0269216310392101 · doi:10.1177/0269216310392101
  4. Hadley G, 2013, Cochrane Database Syst Rev, 2013, CD010270
  5. 10.1136/bmjspcare-2021-003065 · doi:10.1136/bmjspcare-2021-003065
  6. Li Y, 2021, Cochrane Database Syst Rev, 8, CD011108
  7. 10.1016/j.jpainsymman.2017.10.017 · doi:10.1016/j.jpainsymman.2017.10.017
  8. Nicholson AB, 2017, Cochrane Database Syst Rev, 2, CD003971
  9. Schmidt-Hansen M, 2017, Cochrane Database Syst Rev, 8, CD003870
  10. Schmidt-Hansen M, 2015, Cochrane Database Syst Rev, 2015, CD009596
  11. Schuster M, 2018, Dtsch Arztebl Int, 115, 135
  12. Straube C, 2014, Cochrane Database Syst Rev, 2014, CD006601
  13. 10.4103/0973-1482.171368 · doi:10.4103/0973-1482.171368
  14. Wiffen PJ, 2014, Cochrane Database Syst Rev, 2014, CD011056
  15. Wiffen PJ, 2017, Cochrane Database Syst Rev, 5, CD012508
  16. Wiffen PJ, 2015, Cochrane Database Syst Rev, 2015, CD011460
  17. Wiffen PJ, 2017, Cochrane Database Syst Rev, 7, CD012592
  18. Wiffen PJ, 2016, Cochrane Database Syst Rev, 4, CD003868
  19. Zhang X, 2019, Pain Physician, 22, 331
  20. 10.1002/ejp.1548 · doi:10.1002/ejp.1548
  21. 10.1093/jjco/hyy046 · doi:10.1093/jjco/hyy046
  22. 10.1002/ejp.577 · doi:10.1002/ejp.577
  23. 10.21037/apm-20-2336 · doi:10.21037/apm-20-2336
  24. 10.1097/MD.0000000000015505 · doi:10.1097/md.0000000000015505
  25. 10.1016/j.jpainsymman.2016.05.022 · doi:10.1016/j.jpainsymman.2016.05.022
  26. 10.1634/theoncologist.2017-0225 · doi:10.1634/theoncologist.2017-0225
  27. World Health Organization, 2018, WHO Guidelines for the Pharmacological and Radiotherapeutic Management of Cancer Pain in Adults and Adolescents
  28. Bruera E, 2022, Cancer Pain Treatment Selection
  29. Paice JA, 2022, Opioid Management
  30. Berlin J, 2020, Tex Med, 116, 29
  31. 10.1002/cncr.33326 · DOI
  32. US Department of Veterans Affairs, 2016, Opioid Taper Decision Tool. Washington, DC, US Department of Veterans Affairs
  33. 10.1177/0269216308088692 · doi:10.1177/0269216308088692
  34. 10.1097/AJP.0b013e3181929b4f · doi:10.1097/ajp.0b013e3181929b4f
  35. 10.1016/j.jpainsymman.2006.01.001 · doi:10.1016/j.jpainsymman.2006.01.001
  36. US Food and Drug Administration, 2013, Letter to Application Holders: ER/LA Opioid Analgesic Class Labeling Changes and Postmarketing Requirements. Silver Spring, MD, US Food and Drug Administration
  37. 10.1007/s40262-015-0345-4 · doi:10.1007/s40262-015-0345-4
  38. 10.1002/cncr.29688 · doi:10.1002/cncr.29688
  39. 10.1016/j.jpainsymman.2017.07.001 · doi:10.1016/j.jpainsymman.2017.07.001
  40. Rosielle D, 2022, Opioid Equianalgesic Tables Are Broken, Pallimed: A Hospice & Palliative Medicine Blog. Pallimed
  41. Centers for Disease Control, 2021, Drug Overdose Deaths in the US Top 100,000 Annually. Hyattsville, MD, CDC, National Center for Health Statistics
  42. 10.1016/j.jpainsymman.2020.11.033 · doi:10.1016/j.jpainsymman.2020.11.033
  43. American Cancer Society, 2022, Cancer Facts & Figures for African American/Black People 2022-2024
  44. American Cancer Society, 2021, Cancer Facts & Figures for Hispanic/Latino People 2021-2023
  45. 10.1056/NEJMp2115244 · doi:10.1056/nejmp2115244
  46. Marudhai S, 2020, Cureus, 12, e10813
  47. 10.4140/TCP.n.2015.221 · doi:10.4140/tcp.n.2015.221
  48. Gammel LB, 2022, Cureus, 14, e22356
  49. 10.1177/1049909110374454 · doi:10.1177/1049909110374454

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Metadata

Authors
Paice, J. A., Bohlke, K., Barton, D., Craig, D. S., El-Jawahri, A., Hershman, D. L., Kong, L. R., Kurita, G. P., LeBlanc, T. W., Mercadante, S., Novick, K. L. M., Sedhom, R., Seigel, C., Stimmel, J., & Bruera, E.
Venue
Journal of Clinical Oncology
Publisher
American Society of Clinical Oncology (ASCO)
Published
2023-02-01
Volume
41
Issue
4
Pages
914-930
ISSN
  • 0732-183X (ISSN-L)
  • 1527-7755
DOI
10.1200/jco.22.02198
OpenAlex
W4310780757
Cited by
304
References
88
FWCI
53.34
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Use of Opioids for Adults With Pain From Cancer or Cancer Treatment: ASCO Guideline. https://app.cochat.ai/papers/10.1200/jco.22.02198
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Paice, J. A., Bohlke, K., Barton, D., Craig, D. S., El-Jawahri, A., Hershman, D. L., Kong, L. R., Kurita, G. P., LeBlanc, T. W., Mercadante, S., Novick, K. L. M., Sedhom, R., Seigel, C., Stimmel, J., & Bruera, E. (2023). Use of Opioids for Adults With Pain From Cancer or Cancer Treatment: ASCO Guideline. Journal of Clinical Oncology. https://doi.org/10.1200/jco.22.02198

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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.