Tissue-Specific Thyroid Hormone Deprivation and Excess in Monocarboxylate Transporter (Mct) 8-Deficient Mice

Biochemistry, cellular and molecular biology, and physiological roles of the iodothyronine selenodeiodinases

Bianco, A. C., Salvatore, D., Gereben, B., Berry, M. J., & Larsen, P. R. (2002) · Endocrine Reviews · doi:10.1210/edrv.23.1.0455 · Cited by 1,853

Guideline to reference gene selection for quantitative real-time PCR

Radonić, A., Thulke, S., Mackay, I. M., Landt, O., Siegert, W., & Nitsche, A. (2003) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2003.11.177 · Cited by 1,645

Identification of monocarboxylate transporter 8 as a specific thyroid hormone transporter

Friesema, E. C. H., Ganguly, S., Abdalla, A., Fox, J. E. M., Halestrap, A. P., & Visser, T. J. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m300909200 · Cited by 725

Association between mutations in a thyroid hormone transporter and severe X-linked psychomotor retardation

Friesema, E. C., Grueters, A., Biebermann, H., Krude, H., von Moers, A., Reeser, M., Barrett, T. G., Mancilla, E. E., Svensson, J., Kester, M. H., et al. (2004) · The Lancet · doi:10.1016/s0140-6736(04)17226-7 · Cited by 709

A Novel Syndrome Combining Thyroid and Neurological Abnormalities Is Associated with Mutations in a Monocarboxylate Transporter Gene

Dumitrescu, A. M., Liao, X.-H., Best, T. B., Brockmann, K., & Refetoff, S. (2004) · The American Journal of Human Genetics · doi:10.1086/380999 · Cited by 706

Selenium, the Thyroid, and the Endocrine System

Köhrle, J., Jakob, F. J., Contempré, B., & Dumont, J. E. (2005) · Endocrine Reviews · doi:10.1210/er.2001-0034 · Cited by 535

Mutations in SECISBP2 result in abnormal thyroid hormone metabolism

Dumitrescu, A. M., Liao, X.-H., Abdullah, M. S. Y., Lado-Abeal, J., Majed, F. A., Moeller, L. C., Boran, G., Schomburg, L., Weiss, R. E., & Refetoff, S. (2005) · Nature Genetics · doi:10.1038/ng1654 · Cited by 412

Allan-Herndon-Dudley Syndrome and the Monocarboxylate Transporter 8 (MCT8) Gene

Schwartz, C. E., May, M. M., Carpenter, N. J., Rogers, R. C., Martin, J. A., Bialer, M. G., Ward, J. C., Sanabria, J., Marsa, S., Lewis, J. A., et al. (2005) · The American Journal of Human Genetics · doi:10.1086/431313 · Cited by 377

Action of thyroid hormone in brain

Bernal, J. (2002) · Journal of Endocrinological Investigation · doi:10.1007/bf03344003 · Cited by 359

Effects of Maternal Hypothyroidism on the Weight and Thyroid Hormone Content of Rat Embryonic Tissues, before and after Onset of Fetal Thyroid Function*

de Escobar, G. M., PASTOR, R., Obregón, M.-J., & del Rey, F. E. (1985) · Endocrinology · doi:10.1210/endo-117-5-1890 · Cited by 356

Hypothyroxinemia: a subclinical condition affecting neurodevelopment

Berbel, P. J., & Bernal, J. (2010) · Expert Review of Endocrinology & Metabolism · doi:10.1586/eem.10.37 · Cited by 19

Effects of age and soybean isoflavones on hepatic cholesterol metabolism and thyroid hormone availability in acyclic female rats

Šošić‐Jurjević, B., Lütjohann, D., Jarić, I., Miler, M., Milutinović, D. V., Filipović, B. R., Ajdžanović, V. Z., Renko, K., Wirth, E. K., Janković, S., et al. (2017) · Experimental Gerontology · doi:10.1016/j.exger.2017.03.016 · Cited by 17

Distinct Actions of the Thyroid Hormone Transporters Mct8 and Oatp1c1 in Murine Adult Hippocampal Neurogenesis

Mayerl, S. E., Alcaide, M. A., Bauer, R., Schwaninger, M., Heuer, H., & ffrench‐Constant, C. (2022) · Cells · doi:10.3390/cells11030524 · Cited by 17

Triac Treatment Prevents Neurodevelopmental and Locomotor Impairments in Thyroid Hormone Transporter Mct8/Oatp1c1 Deficient Mice

Chen, J., Salveridou, E., Liebmann, L., Sundaram, S. M., Doycheva, D., Markova, B., Hübner, C. A., Boelen, A., Visser, W. E., Heuer, H., et al. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms24043452 · Cited by 17

Prevalence and functional analysis of the S107P polymorphism (rs6647476) of the monocarboxylate transporter 8 (SLC16A2) gene in the male population of north‐west Spain (Galicia)

Lago‐Lestón, R. M., Iglesias, M., San‐José, E., Areal, C., Eiras, A., Araújo‐Vilar, D., Lado‐Abeal, J., & Domínguez‐Gerpe, L. (2008) · Clinical Endocrinology · doi:10.1111/j.1365-2265.2008.03377.x · Cited by 17

Role of Monocarboxylate Anion Transporter 8 (MCT8) in Thyroid Hormone Transport: Answers from Mice

Bernal, J. (2006) · Endocrinology · doi:10.1210/en.2006-0695 · Cited by 17

Erratum: Thyroid hormone transporters—functions and clinical implications

Bernal, J., Guadaño‐Ferraz, A., & Morte, B. (2015) · Nature Reviews Endocrinology · doi:10.1038/nrendo.2015.113 · Cited by 17

Thyroid hormone transporter Mct8/Oatp1c1 deficiency compromises proper oligodendrocyte maturation in the mouse CNS

Mayerl, S. E., & Heuer, H. (2023) · Neurobiology of Disease · doi:10.1016/j.nbd.2023.106195 · Cited by 15

Understanding the Hypothalamus-Pituitary-Thyroid Axis in Mct8 Deficiency

Müller, J., & Heuer, H. (2012) · European Thyroid Journal · doi:10.1159/000339474 · Cited by 16

An Essential Physiological Role for MCT8 in Bone in Male Mice

Leitch, V. D., Cosmo, C. D., Liao, X.-H., O'Boy, S., Galliford, T. M., Evans, H., Croucher, P. I., BOYDE, A., Dumitrescu, A. M., Weiss, R. E., et al. (2017) · Endocrinology · doi:10.1210/en.2017-00399 · Cited by 17

Functional Characterization of Xenopus Thyroid Hormone Transporters mct8 and oatp1c1

Mughal, B. B., Leemans, M., de Souza, E. C. L., Mével, S. L., Špirhanzlová, P., Visser, T. J., Fini, J., & DEMENEIX, B. A. (2017) · Endocrinology · doi:10.1210/en.2017-00108 · Cited by 17

Tissue-specific effects of mutations in the thyroid hormone transporter MCT8

Kersseboom, S., & Visser, T. J. (2011) · Arquivos Brasileiros de Endocrinologia & Metabologia · doi:10.1590/s0004-27302011000100001 · Cited by 15

Triiodothyroacetic Acid Treatment in MCT8 Deficiency: A Word of Nuance

Visser, W. E., Heuer, H., & Visser, T. J. (2016) · Thyroid · doi:10.1089/thy.2016.0191 · Cited by 15

Finding the Way into the Brain without MCT8

Visser, W. E., & Visser, T. J. (2012) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2012-3759 · Cited by 14

MCT8 Deficiency in Male Mice Mitigates the Phenotypic Abnormalities Associated With the Absence of a Functional Type 3 Deiodinase

Stohn, J. P., Martinez, M. E., Matoin, K. L., Morte, B., Bernal, J., Galton, V. A., Germain, D. L. S., & Hernández, A. (2016) · Endocrinology · doi:10.1210/en.2016-1162 · Cited by 14

Intracerebroventricular administration of the thyroid hormone analog TRIAC increases its brain content in the absence of MCT8

Bárez‐López, S., Grijota-Martínez, C., Liao, X.-H., Refetoff, S., & Guadaño‐Ferraz, A. (2019) · PLoS ONE · doi:10.1371/journal.pone.0226017 · Cited by 16

Thyroid Hormone Transporter Defects

ters, A. G. U. (2007) · KARGER eBooks · doi:10.1159/000106823 · Cited by 14

High T3, Low T4 Serum Levels in Mct8 Deficiency Are Not Caused by Increased Hepatic Conversion through Type I Deiodinase

Wirth, E. K., Rijntjes, E., Meyer, F. I., Köhrle, J., & Schweizer, U. (2015) · European Thyroid Journal · doi:10.1159/000381021 · Cited by 13

Dissecting the role of regulators of thyroid hormone availability in early brain development: Merits and potential of the chicken embryo model

Vancamp, P., & Darras, V. (2017) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2017.01.045 · Cited by 13

Characterization and Proteomic-Transcriptomic Investigation of Monocarboxylate Transporter 6 Knockout Mice: Evidence of a Potential Role in Glucose and Lipid Metabolism

Jones, R. S., Tu, C., Zhang, M., Qu, J., & Morris, M. E. (2019) · Molecular Pharmacology · doi:10.1124/mol.119.116731 · Cited by 13

Allan-Herndon-Dudley-Syndrome: Considerations about the Brain Phenotype with Implications for Treatment Strategies

Krude, H., Biebermann, H., Schuelke, M., Müller, T. D., & Tschöp, M. H. (2020) · Experimental and Clinical Endocrinology & Diabetes · doi:10.1055/a-1108-1456 · Cited by 12

Is a low level of free thyroxine in the maternal circulation associated with altered endothelial function in gestational diabetes?

Guzmán‐Gutiérrez, E., Veas, C., Leiva, A., Escudero, C., & Sobrevía, L. (2014) · Frontiers in Pharmacology · doi:10.3389/fphar.2014.00136 · Cited by 13

RNA polymerase II phosphorylation at serine 2 and histone H3 tri-methylation at lysine 36 are key steps for thyroid hormone receptor β gene activation by thyroid hormone in Rana catesbeiana tadpole liver

Mochizuki, K., Ishihara, A., Goda, T., & Yamauchi, K. (2011) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2011.12.097 · Cited by 13

Changes in Hepatic TRβ Protein Expression, Lipogenic Gene Expression, and Long-Chain Acylcarnitine Levels During Chronic Hyperthyroidism and Triiodothyronine Withdrawal in a Mouse Model

Ohba, K., Sinha, R. A., Singh, B. K., Iannucci, L. F., Zhou, J., Kovalik, J., Liao, X.-H., Refetoff, S., Sng, J., Leow, M. K., et al. (2017) · Thyroid · doi:10.1089/thy.2016.0456 · Cited by 13

Allan–Herndon–Dudley syndrome with unusual profound sensorineural hearing loss

Gagliardi, L., Nataren, N. J., Feng, J., SCHREIBER, A. W., Hahn, C. N., Conwell, L. S., Coman, D. J., & Scott, H. S. (2015) · American Journal of Medical Genetics Part A · doi:10.1002/ajmg.a.37075 · Cited by 13

Adipose Tissue μ-Crystallin Is a Thyroid Hormone-Binding Protein Associated With Systemic Insulin Sensitivity

Serrano, M., Moreno, M., Ortega, F. J., Xifra, G., Ricart, W., Moreno‐Navarrete, J. M., & Fernández‐Real, J. M. (2014) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2014-1327 · Cited by 12

Membrane transporters and the diseases corresponding to functional defects

Lai, Y. (2013) · Elsevier eBooks · doi:10.1533/9781908818287.1 · Cited by 13

Epitope Recognition in HLA-DR3 Transgenic Mice Immunized to TSH-R Protein or Peptides

Inaba, H., Moise, L., Martin, W. D., Groot, A. S. D., Desrosiers, J., Tassone, R., Buchman, G. W., Akamizu, T., & DeGroot, L. J. (2013) · Endocrinology · doi:10.1210/en.2013-1033 · Cited by 12

Structural insights into brain thyroid hormone transport via MCT8 and OATP1C1

Ge, Y., Dou, T., Nguyen, T. U., Yadav, G. P., Wensel, T. G., Jiang, J., & Huang, P. (2025) · Cell · doi:10.1016/j.cell.2025.06.032 · Cited by 12

CRISPR/Cas9-mediated knockout of Mct8 reveals a functional involvement of Mct8 in testis and sperm development in a rat

Bae, H. S., Jin, Y.-K., Ham, S., Kim, H. K., Shin, H. J., Cho, G., Lee, K. J., Lee, H., Kim, K. M., Koo, O. J., et al. (2020) · Scientific Reports · doi:10.1038/s41598-020-67594-2 · Cited by 11

Intranasal delivery of Thyroid hormones in MCT8 deficiency

Grijota-Martínez, C., Bárez‐López, S., Ausó, E., Refetoff, S., Frey, W. H., & Guadaño‐Ferraz, A. (2020) · PLoS ONE · doi:10.1371/journal.pone.0236113 · Cited by 12

A CRISPR/Cas9-engineered avatar mouse model of monocarboxylate transporter 8 deficiency displays distinct neurological alterations

Valcárcel-Hernández, V., Guillén-Yunta, M., Bueno-Arribas, M., Montero‐Pedrazuela, A., Grijota-Martínez, C., Markossian, S., García-Aldea, Á., Flamant, F., Bárez‐López, S., & Guadaño‐Ferraz, A. (2022) · Neurobiology of Disease · doi:10.1016/j.nbd.2022.105896 · Cited by 13

Defective thyroid hormone transport to the brain leads to astroglial alterations

Guillén-Yunta, M., García-Aldea, Á., Valcárcel-Hernández, V., Sanz-Bógalo, A., Muñoz‐Moreno, E., Matheus, M. G., Grijota-Martínez, C., Montero‐Pedrazuela, A., Guadaño‐Ferraz, A., & Bárez‐López, S. (2024) · Neurobiology of Disease · doi:10.1016/j.nbd.2024.106621 · Cited by 11

Toward a treatment for thyroid hormone transporter MCT8 deficiency – achievements and challenges

Markova, B., Mayerl, S. E., & Heuer, H. (2024) · European Thyroid Journal · doi:10.1530/etj-24-0286 · Cited by 10

Sodium Phenylbutyrate Rescues Thyroid Hormone Transport in Brain Endothelial-Like Cells

Braun, D., Bohleber, S., Vatine, G. D., Svendsen, C. N., & Schweizer, U. (2022) · Thyroid · doi:10.1089/thy.2021.0643 · Cited by 10

“Thyroglobulin Storage, Processing and Degradation for Thyroid Hormone Liberation”

Brix, K., Qatato, M., Szumska, J., Venugopalan, V., & Rehders, M. (2019) · Springer eBooks · doi:10.1007/978-3-319-72102-6_3 · Cited by 10

Hear, Hear! Thyroid Hormone Transporters in Cochlear Development

Heuer, H. (2011) · Endocrinology · doi:10.1210/en.2011-1722 · Cited by 10

The Thyroid Hormone Transporter Mct8 Restricts Cathepsin-Mediated Thyroglobulin Processing in Male Mice through Thyroid Auto-Regulatory Mechanisms That Encompass Autophagy

Venugopalan, V., Al-Hashimi, A., Rehders, M., Golchert, J., Reinecke, V., Homuth, G., Völker, U., Manirajah, M., Touzani, A., Weber, J., et al. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22010462 · Cited by 10

Iodine deficiency up-regulates monocarboxylate transporter 8 expression of mouse thyroid gland

Hu, Z., Zhuo, X., Shi, Y., Liu, X., Yuan, J., Li, L., & Sun, Y. (2014) · Chinese Medical Journal · doi:10.3760/cma.j.issn.0366-6999.20141314 · Cited by 10

Maintaining the thyroid gland in mutant thyroglobulin–induced hypothyroidism requires thyroid cell proliferation that must continue in adulthood

Zhang, X., Malik, B., Young, C., Zhang, H., Larkin, D. D., Liao, X.-H., Refetoff, S., Liu, M. R., & Arvan, P. R. (2022) · Journal of Biological Chemistry · doi:10.1016/j.jbc.2022.102066 · Cited by 9

Mathematical modeling and simulation of thyroid homeostasis: Implications for the Allan-Herndon-Dudley syndrome

Wolff, T. M., Veil, C., Dietrich, J. W., & Müller, M. A. (2022) · Frontiers in Endocrinology · doi:10.3389/fendo.2022.882788 · Cited by 9

Role of type 1 and 2 deiodinases in thyroid metabolism (review)

Artykbaeva, G. (2016) · Problems of Endocrinology · doi:10.14341/probl201662246-52 · Cited by 9

Genetic and Neurological Deficiencies in the Visual System of mct8 Mutant Zebrafish

Rozenblat, R., Tovin, A., Zada, D., Lebenthal-Loinger, I., Lerer‐Goldshtein, T., & Appelbaum, L. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23052464 · Cited by 10

Deletion of Exon 1 of the SLC16A2 Gene: A Common Occurrence in Patients with Allan-Herndon-Dudley Syndrome

Teresa, B. G., Angel, A. G., Reyna‐Fabián, M. E., Ruiz-Reyes, M. D. L. L., Calzada-León, R., Pérez-Enríquez, B., & Alcántara‐Ortigoza, M. A. (2014) · Thyroid · doi:10.1089/thy.2014.0284 · Cited by 9

Resistance to Thyroid Hormone

Gurnell, M., Visser, T. J., Beck‐Peccoz, P., & Chatterjee, K. (2015) · Elsevier eBooks · doi:10.1016/b978-0-323-18907-1.00095-0 · Cited by 9

Insights on the role of thyroid hormone transport in neurosensory organs and implication for the Allan–Herndon–Dudley syndrome

García-Aldea, Á., Guillén-Yunta, M., Valcárcel-Hernández, V., Montero‐Pedrazuela, A., Guadaño‐Ferraz, A., & Bárez‐López, S. (2024) · European Thyroid Journal · doi:10.1530/etj-23-0241 · Cited by 9

The Protein Translocation Defect of MCT8L291R Is Rescued by Sodium Phenylbutyrate

Braun, D., & Schweizer, U. (2020) · European Thyroid Journal · doi:10.1159/000507439 · Cited by 8

Thyroid Hormones and Brain Development

Bernal, J. (2009) · Elsevier eBooks · doi:10.1016/b978-008088783-8.00063-2 · Cited by 8

Inactivation of Thyroid Hormone Transporters Mct8/Oatp1c1 in Mouse Brain Endothelial Cells Causes Region-Specific Alterations in Central Thyroid Hormone Signaling

Alevyzaki, A., Markova, B., Angelis, M. D., Müller, T. D., Chandrasekar, A., Müller-Fielitz, H., Schwaninger, M., Boelen, A., Führer-Sakel, D., Mayerl, S. E., et al. (2025) · Thyroid · doi:10.1089/thy.2025.0089 · Cited by 7

Thyroid hormone analogues: Promising therapeutic avenues to improve the neurodevelopmental outcomes of intrauterine growth restriction

Chincarini, G., Walker, D. W., Wong, F. Y., Richardson, S. J., Cumberland, A. L., & Tolcos, M. (2024) · Journal of Neurochemistry · doi:10.1111/jnc.16124 · Cited by 7

IGSF1 Deficiency Leads to Reduced TSH Production Independent of Alterations in Thyroid Hormone Action in Male Mice

Brûlé, E., Silander, T. L., Wang, Y., Zhou, X., Bąk, B., Groeneweg, S., & Bernard, D. J. (2022) · Endocrinology · doi:10.1210/endocr/bqac092 · Cited by 6

A 7‐month‐old male with Allan‐Herndon‐Dudley syndrome and the power of T3

Langley, K. G., Trau, S. P., Bean, L. J., Narravula, A., & Vergano, S. A. S. (2015) · American Journal of Medical Genetics Part A · doi:10.1002/ajmg.a.36970 · Cited by 7

MCT8: From gene to disease and therapeutic approach

Kersseboom, S., & Visser, T. J. (2011) · Annales d Endocrinologie · doi:10.1016/j.ando.2011.03.003 · Cited by 7

Update in Thyroidology

Ridgway, E. C., Tomer, Y., & McLachlan, S. M. (2007) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2007-1855 · Cited by 7

Thyroid Hormone Metabolism

Germain, D. L. S. (2010) · Elsevier eBooks · doi:10.1016/b978-1-4160-5583-9.00075-7 · Cited by 7

Role of the Thyroid Gland in Expression of the Thyroid Phenotype of Sbp2-Deficient Mice

Fujisawa, H., Korwutthikulrangsri, M., Fu, J., Liao, X.-H., & Dumitrescu, A. M. (2019) · Endocrinology · doi:10.1210/endocr/bqz032 · Cited by 6

Thyroide hormone resistance syndromes

Bernal, J. (2011) · Endocrinología y Nutrición (English Edition) · doi:10.1016/s2173-5093(11)70043-5 · Cited by 6

Syndromes of Impaired Sensitivity to Thyroid Hormone

Weiss, R. E., Dumitrescu, A. M., & Refetoff, S. (2015) · Elsevier eBooks · doi:10.1016/b978-0-12-800892-8.00009-9 · Cited by 6

Increased seizure susceptibility in thyroid hormone transporter Mct8/Oatp1c1 knockout mice is associated with altered neurotransmitter systems development

Alcaide, M. A., Bauer, R., Führer‐Sakel, D., Heuer, H., & Mayerl, S. E. (2025) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2025.102731 · Cited by 5

Characteristics of Allan-Herndon-Dudley Syndrome in Chinese children: Identification of two novel pathogenic variants of the SLC16A2 gene

Zhang, Q., Yang, Q., Zhou, X., Qin, Z., Yi, S., & Luo, J. (2022) · Frontiers in Pediatrics · doi:10.3389/fped.2022.1050023 · Cited by 5

The affinity of transthyretin for T3 or T4 does not determine which form of the hormone accumulates in the choroid plexus

Richardson, S. J., Herck, S. V., Delbaere, J., McAllan, B. M., & Darras, V. (2017) · General and Comparative Endocrinology · doi:10.1016/j.ygcen.2017.09.012 · Cited by 5

Intracerebroventricular High Doses of 3,3′,5-Triiodothyroacetic Acid at Juvenile Stages Improve Peripheral Hyperthyroidism and Mediate Thyromimetic Effects in Limited Brain Regions in a Mouse Model of Monocarboxylate Transporter 8 Deficiency

Grijota-Martínez, C., Montero‐Pedrazuela, A., Hidalgo-Álvarez, J., Bárez‐López, S., & Guadaño‐Ferraz, A. (2022) · Thyroid · doi:10.1089/thy.2022.0562 · Cited by 5

Tissue-Specific Function of Thyroid Hormone Transporters: New Insights from Mouse Models

Salveridou, E., Mayerl, S. E., Sundaram, S. M., Markova, B., & Heuer, H. (2019) · Experimental and Clinical Endocrinology & Diabetes · doi:10.1055/a-1032-8328 · Cited by 5

Thyroid Hormones and Brain Development

Bernal, J. (2016) · Elsevier eBooks · doi:10.1016/b978-0-12-803592-4.00100-0 · Cited by 5

Sex-specific DNA methylation changes in placental thyroid hormone regulatory genes following prenatal exposure to flame retardants

Luan, M., Zhu, H., Yang, F., Liang, H., Song, X., Jin, L., Ji, H., Yuan, W., Wu, Q., Su, X., et al. (2025) · Ecotoxicology and Environmental Safety · doi:10.1016/j.ecoenv.2025.118840 · Cited by 4

Heterogeneous Clinical Characteristics of Allan-Herndon-Dudley Syndrome with SLC16A2 Mutations

Han, J. Y., Lee, S., Woo, H., Kim, S. Y., Kim, H., Lim, B. C., Hwang, H. Y., Choi, J., Kim, K. J., & Chae, J. (2021) · Annals of Child Neurology · doi:10.26815/acn.2021.00423 · Cited by 4

Resistance to Thyroid Hormone (RTH) and Resistance to TSH (RTSH)

Dumitrescu, A. M., & Cohen, R. (2018) · Springer eBooks · doi:10.1007/978-3-319-73782-9_20 · Cited by 4

Thyroid Abnormalities in Heart Failure

Danzi, S. E., & Klein, I. L. (2022) · Cardiology Clinics · doi:10.1016/j.ccl.2021.12.002 · Cited by 4

Identification of region-specific genes in the early chicken endoderm

Kimura, W., Alev, C., Sheng, G., Jakt, L. M., Yasugi, S., & Fukuda, K. (2010) · Gene Expression Patterns · doi:10.1016/j.gep.2010.11.002 · Cited by 4

Mathematical Modeling of Thyroid Homeostasis: Implications for the Allan-Herndon-Dudley SyndromePreprint

Wolff, T. M., Veil, C., Dietrich, J. W., & Müller, M. A. (2022) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2022.01.24.476744 · Cited by 4

Syndromes of Reduced Sensitivity to Thyroid Hormone

Weiss, R. E., Dumitrescu, A. M., & Refetoff, S. (2010) · Elsevier eBooks · doi:10.1016/b978-0-12-374430-2.00010-9 · Cited by 3

Diiodothyropropionic acid (DITPA) cross-reacts with thyroid function assays on different immunoassay platforms

Leung, E. K. Y., Yi, X., Refetoff, S., & Yeo, K.-T. J. (2015) · Clinica Chimica Acta · doi:10.1016/j.cca.2015.12.008 · Cited by 3

Differential expression and immunoreactivity of thyroid hormone transporters MCT8 and OATP1C1 in rat ovary

Luis, E., Fernández, Y., Alvarado-Olivarez, M., Juárez-Santacruz, L., Garcı́a-Nieto, E., & Anaya‐Hernández, A. (2019) · Acta Histochemica · doi:10.1016/j.acthis.2019.151440 · Cited by 3

Signal Transduction in Child Health: Closing the Gap Between Clinical and Basic ResearchA report on the third NICHe Conference, “New Inroads to Child Health—Child Health and Signal Transduction,” Varberg, Sweden, 21 to 23 May 2010

Chan, L. F., Albertsson-Wikland, K. G., Camacho‐Hübner, C., & Hochberg, Z. (2010) · Science Signaling · doi:10.1126/scisignal.3143mr3 · Cited by 3

Identification of Iodotyrosines as Novel Substrates for the Thyroid Hormone Transporter MCT8

Groeneweg, S., Zevenbergen, C., de Souza, E. C. L., van Geest, F. S., Kloeckener‐Gruissem, B., Laczkó, E., Camargo, S. M. R., Meima, M. E., Peeters, R. P., & Visser, W. E. (2024) · Thyroid · doi:10.1089/thy.2023.0551 · Cited by 2

The amino acid transporter Mct10/Tat1 is important to maintain the TSH receptor at its canonical basolateral localization and assures regular turnover of thyroid follicle cells in Male mice

Venugopalan, V., Al-Hashimi, A., Weber, J., Rehders, M., Qatato, M., Wirth, E. K., Schweizer, U., Heuer, H., Verrey, F., & Brix, K. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22115776 · Cited by 2

Thyroid-Disrupting Chemicals as Developmental Neurotoxicants

Sharlin, D. S. (2015) · Elsevier eBooks · doi:10.1016/b978-0-12-800228-5.00008-x · Cited by 2

Resistance to Thyroid Hormone and TSH Receptor Mutations

Cohen, R. (2013) · Humana Press eBooks · doi:10.1007/978-1-60761-395-4_18 · Cited by 2

Animal Models to Study Thyroid Hormone Action in Neurodevelopment

Shimokawa, N., & Koibuchi, N. (2016) · Contemporary clinical neuroscience · doi:10.1007/978-1-4939-3737-0_6 · Cited by 1

Deiodination and Peripheral Metabolism of Thyroid Hormone

Dentice, M., & Salvatore, D. (2019) · Springer eBooks · doi:10.1007/978-3-319-72102-6_5 · Cited by 1

Sciatic nerve analysis in thyroid hormone transporters Mct8 and Oatp1c1 knockout mice

Mayerl, S. E., Alcaide, M. A., Bauer, R., & Heuer, H. (2025) · European Thyroid Journal · doi:10.1530/etj-24-0248 · Cited by 1

Altered cerebral thyroid hormone, WNT and NOTCH signalling and impaired myelination following intrauterine growth restriction in rats

Azhan, A., Cumberland, A. L., Chincarini, G., Barresi, M., Hale, N., Rowitch, D. H., Wong, F., Walker, D. W., & Tolcos, M. (2025) · Neuroscience · doi:10.1016/j.neuroscience.2025.12.068 · Cited by 1

Neuron-specific expression of murine thyroid hormone transporters Mct8 and Oatp1c1 is dispensable for hippocampus-dependent neuronal functions

Alcaide-Martin, A., Jaber, R., Boelen, A., Heuer, H., & Mayerl, S. E. (2026) · Frontiers in Endocrinology · doi:10.3389/fendo.2026.1781214 · Cited by 1

Cell Transport Defects

Dumitrescu, A. M., & Refetoff, S. (2009) · Elsevier eBooks · doi:10.1016/b978-1-4160-4745-2.00022-5 · Cited by 1

Role of Thyrotropin-Releasing Hormone in the Regulation of the Thyroid Axis

Hollenberg, A. N. (2009) · Elsevier eBooks · doi:10.1016/b978-1-4160-4745-2.00006-7 · Cited by 1

In vitro blood–brain barrier model derived from human iPS cells and its applications

Zhang, H., Yamaguchi, T., & Kawabata, K. (2021) · Elsevier eBooks · doi:10.1016/b978-0-12-822231-7.00003-5 · Cited by 1

La resistenza e le altre sindromi da ridotta sensibilità agli ormoni tiroidei

Cosmo, C. D. (2022) · L Endocrinologo · doi:10.1007/s40619-021-01008-x · Cited by 1

Thyroid Hormone Production and Transplacental Transfer in the “Mother–Fetus” System during Gestational Hyperhomocysteinemia

Shcherbitskaia, A. D., Kovalenko, A. A., Milyutina, Y. P., & Vasilev, D. S. (2022) · Neurochemical Journal · doi:10.1134/s1819712422030102 · Cited by 1

Regulation of brain metabolism by peripheral nutritional signals: the role of blood-brain barrier in health and disease

Zhang, D., Guo, Z., Yang, Y., & Chang, J. (2022) · Journal of Holistic Integrative Pharmacy · doi:10.1016/s2707-3688(23)00061-4 · Cited by 2

Les hormones thyroïdiennes régulent le destin des cellules souches neurales

Remaud, S., & DEMENEIX, B. A. (2019) · Biologie Aujourd hui · doi:10.1051/jbio/2019007 · Cited by 1

Genetic Influences on Thyroid Function Tests

van der Deure, W. M., Medici, M., Peeters, R. P., & Visser, T. J. (2010) · Endocrine updates · doi:10.1007/978-1-4419-1485-9_2 · Cited by 1

Manifestazioni cliniche delle mutazioni del trasportatore degli ormoni tiroidei MCT8

Cosmo, C. D. (2013) · L Endocrinologo · doi:10.1007/bf03346046

Papel do TR na termogênese induzida pela dieta.

Amorim, B. S. (2010) · doi:10.11606/d.42.2010.tde-19052010-130712

Studien zum Transport von Schilddrüsenhormonen durch Membrantransporter der MCT- und LAT-Familie

Kinne, A. (2011) · Universitätsbibliothek der FU Berlin Hochschulschriftenstelle u. Dokumentenserver · doi:10.17169/refubium-15773

Monogenic Thyroid Disorder

Cho, S. W., & Park, Y. J. (2012) · Journal of Korean Thyroid Association · doi:10.11106/jkta.2012.5.2.83

Thyroid physiology becomes more complicated

Larsen, P. R. (2007) · Nature Clinical Practice Endocrinology & Metabolism · doi:10.1038/ncpendmet0551

Os hormônios tireoideanos e o desenvolvimento esquelético fetal e pós-natal: estudo do padrão de expressão dos transportadores e das selenodesiodases das iodotironinas.

Capelo, L. P. (2009) · Digital Library of Theses and Dissertations (Universidade de São Paulo) · doi:10.11606/t.42.2009.tde-06042009-160228

Genetic Defects in Thyroid Hormone Synthesis and Action∗

Macchia, P. E., & Fenzi, G. (2015) · Elsevier eBooks · doi:10.1016/b978-0-323-18907-1.00094-9

Research Changes in the central component of the hypothalamus-pituitary-thyroid axis in a rabbit model of prolonged critical illness

Mebis, L., Debaveye, Y. A., Ellger, B., Derde, S., Ververs, E.-J., Langouche, L., Darras, V., Fliers, E., Visser, T. J., & den Berghe, G. V. (2009)

Deficit in Thyroid Hormone Transporters and Brain Development

Suzuki, T., & Abe, T. (2016) · Contemporary clinical neuroscience · doi:10.1007/978-1-4939-3737-0_11

Impact of monocarboxylate transporter-8 deficiency on the hypothalamus-pituitary-thyroid axis in mice

Trajkovic-Arsic, M., Müller, J., Darras, V. M., Groba, C., Lee, S., Weih, D., Bauer, K., Visser, T. J., & Heuer, H. (2010) · Endocrinology · doi:10.1210/en.2010-0593 · Cited by 87

Consequences of Monocarboxylate Transporter 8 Deficiency for Renal Transport and Metabolism of Thyroid Hormones in Mice

Trajkovic‐Arsic, M., Visser, T. J., Darras, V., Friesema, E. C. H., Schlott, B., Mittag, J., Bauer, K., & Heuer, H. (2009) · Endocrinology · doi:10.1210/en.2009-1053 · Cited by 63

The use of mice deficient in MCT8 to identify a mechanism regulating thyroid hormone secretion

DI COSMO, C. A. G. (2010) · Electronic Theses and Dissertations Repository (University of Pisa)

The pathophysiological consequences of thyroid hormone transporter deficiencies: Insights from mouse models

Heuer, H., & Visser, T. J. (2013) · Biochimica et Biophysica Acta (BBA) - General Subjects · doi:10.1016/j.bbagen.2012.04.009 · Cited by 64

Changes in Thyroid Status During Perinatal Development of MCT8-Deficient Male Mice

Ferrara, A. M., Liao, X.-H., Gil-Ibáñez, P., Marcinkowski, T., Bernal, J., Weiss, R. E., Dumitrescu, A. M., & Refetoff, S. (2013) · Endocrinology · doi:10.1210/en.2012-2031 · Cited by 70