Adrenal Replacement Therapy: Time for an Inward Look to the Medulla?
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In patients with adrenal insufficiency, the decrease in intra-adrenal cortisol concentrations leads to a decrease in catecholamine synthesis as a result of decreased phenylethanolamine N-methyltransferase activity.
“In patients with AI, the decrease in intra-adrenal cortisol concentrations leads to a decrease in catecholamine synthesis (as a result of decrease PNMT activity).27”
From Adrenal crisis: prevention and management in adult patients (2019) · cites this paper as [27]
Cites
Adrenomedullary dysplasia and hypofunction in patients with classic 21-hydroxylase deficiency.
Merke, D. P., Chrousos, G. P., Eisenhofer, G., Weise, M., Keil, M. F., Rogol, A. D., Van Wyk, J. J., & Bornstein, S. R. (2000) · New England Journal of Medicine · doi:10.1056/nejm200011093431903 · Cited by 266 · see citing works
Weise, M., Drinkard, B., Mehlinger, S. L., Holzer, S. M., Eisenhofer, G., Charmandari, E., Chrousos, G. P., & Merke, D. P. (2004) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2003-032051 · Cited by 75 · see citing works
Zuckerman-Levin, N., Tiosano, D., Eisenhofer, G., Bornstein, S., & Hochberg, Z. (2001) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.86.12.8106 · Cited by 72 · see citing works
Weise, M., Mehlinger, S. L., Drinkard, B., Rawson, E., Charmandari, E., Hiroi, M., Eisenhofer, G., Yanovski, J. A., Chrousos, G. P., & Merke, D. P. (2004) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2003-030634 · Cited by 67 · see citing works
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Adrenal crisis: prevention and management in adult patients
Dineen, R., Thompson, C. J., & Sherlock, M. (2019) · Therapeutic Advances in Endocrinology and Metabolism · doi:10.1177/2042018819848218 · Cited by 123 · see citing works
Adrenal insufficiency in critical illness
Cooper, M. S., & Stewart, P. M. (2007) · Journal of Intensive Care Medicine · doi:10.1177/0885066607307832 · Cited by 97 · see citing works
Self-citation
- Authors
- Stewart, P. M.
- Affiliations
- Queen Elizabeth Hospital Birmingham (GB)
- Corresponding author
- Stewart, Paul M.
- ORCID
- Stewart, Paul M.
- Venue
- The Journal of Clinical Endocrinology & Metabolism
- Publisher
- The Endocrine Society
- Published
- 2004-08
- Volume
- 89
- Issue
- 8
- Pages
- 3677-3678
- ISSN
- 0021-972X (ISSN-L)
- 1945-7197
- OpenAlex
- W1982345102
- Cited by
- 8
- References
- 4
- Citations by year
- 2019: 1 · 2013: 1
- FWCI
- 0.97
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- The Journal of Clinical Endocrinology & Metabolism (publishedVersion)
- PubMed (publishedVersion)
- University of Birmingham Research Portal (University of Birmingham) (submittedVersion)
- Topics
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Adrenal Hormones and Disorders
- Health Sciences › Medicine › Surgery › Adrenal and Paraganglionic Tumors
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Hormonal and reproductive studies
- Keywords
- adrenal medulla, adrenal insufficiency, glucocorticoids, mineralocorticoids, adrenal cortex hormones
- MeSH terms
- Adrenal Insufficiency, Adrenal Hyperplasia, Congenital, Adrenal Medulla, Animals, Glucocorticoids, Humans, Hormone Replacement Therapy
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
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