SDHA Immunohistochemistry Detects Germline SDHA Gene Mutations in Apparently Sporadic Paragangliomas and Pheochromocytomas

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SDH5 , a Gene Required for Flavination of Succinate Dehydrogenase, Is Mutated in Paraganglioma

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SDHA is a tumor suppressor gene causing paraganglioma

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Carbonic anhydrase 9 immunohistochemistry as a tool to predict or validate germline and somatic VHL mutations in pheochromocytoma and paraganglioma—a retrospective and prospective study

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Germline SDHA mutations in children and adults with cancerPreprint

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The Genetic Basis of Pheochromocytoma and Paraganglioma: Implications for Management

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Mitochondrial complex II and genomic imprinting in inheritance of paraganglioma tumors

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Metabolomics, machine learning and immunohistochemistry to predict succinate dehydrogenase mutational status in phaeochromocytomas and paragangliomas

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A New Specific Succinate-Glutamate Metabolomic Hallmark in Sdhx-Related Paragangliomas

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The genetics of paragangliomas

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The VHL/HIF Axis in the Development and Treatment of Pheochromocytoma/Paraganglioma

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Contemporary management of paragangliomas of the head and neck

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Old, New, and Emerging Immunohistochemical Markers in Pheochromocytoma and Paraganglioma

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Imaging Features of Succinate Dehydrogenase–deficient Pheochromocytoma-Paraganglioma Syndromes

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Continued Tumor Reduction of Metastatic Pheochromocytoma/Paraganglioma Harboring Succinate Dehydrogenase Subunit B Mutations with Cyclical Chemotherapy

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Significance of Alpha-inhibin Expression in Pheochromocytomas and Paragangliomas

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Pathogenicity and Penetrance of Germline SDHA Variants in Pheochromocytoma and Paraganglioma (PPGL)

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The Role of Immunohistochemistry and Molecular Analysis of Succinate Dehydrogenase in the Diagnosis of Endocrine and Non-Endocrine Tumors and Related Syndromes

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A xenograft and cell line model of SDH-deficient pheochromocytoma derived from Sdhb+/− rats

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Epigenetic and metabolic reprogramming of SDH-deficient paragangliomas

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Current views on cell metabolism in SDHx-related pheochromocytoma and paraganglioma

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Molecular pathogenesis of tumorigenesis caused by succinate dehydrogenase defect

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Yeast model for evaluating the pathogenic significance of SDHB, SDHC and SDHD mutations in PHEO-PGL syndrome

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Potential Pitfalls of SDH Immunohistochemical Detection in Paragangliomas and Phaeochromocytomas Harbouring Germline SDHx Gene Mutation

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Pheochromocytoma and paraganglioma: implications of germline mutation investigation for treatment, screening, and surveillance

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The metabolic genomic atlas reveals potential drivers and clinically relevant insights into the etiology of esophageal squamous cell carcinoma

Liu, X., Hong, R., Du, P., Yang, D., He, M., Wu, Q., Li, L., Wang, Y., Chen, J., Min, Q., et al. (2022) · Theranostics · doi:10.7150/thno.70814 · Cited by 14

A Clinical Roadmap to Investigate the Genetic Basis of Pediatric Pheochromocytoma: Which Genes Should Physicians Think About?

Pereira, B. D., Silva, T., Bernardo, A. T., César, R., Luíz, H. V., Pacák, K., & Mota‐Vieira, L. (2018) · International Journal of Endocrinology · doi:10.1155/2018/8470642 · Cited by 13

Interaction of germline variants in a family with a history of early‐onset clear cell renal cell carcinoma

Nicolas, É., Demidova, E. V., Iqbal, W., Serebriiskii, I. G., Vlasenkova, R., Ghatalia, P., Zhou, Y., Rainey, K., Forman, A. F., Dunbrack, R. L., et al. (2019) · Molecular Genetics & Genomic Medicine · doi:10.1002/mgg3.556 · Cited by 13

Metabolomics in the Diagnosis of Pheochromocytoma and Paraganglioma

Dwight, T., Kim, E., Novos, T., & Clifton-Bligh, R. J. (2019) · Hormone and Metabolic Research · doi:10.1055/a-0926-3790 · Cited by 14

Genetics of Pheochromocytoma and Paraganglioma

Pereira, B. D., Luíz, H. V., Ferreira, A. G., & Portugal, J. (2019) · Codon Publications eBooks · doi:10.15586/paraganglioma.2019.ch1 · Cited by 12

Surveillance of succinate dehydrogenase gene mutation carriers: Insights from a nationwide cohort

Martins, R. G., Cunha, N., Simões, H., Matos, M. J., Silva, J., Torres, I., Rodrigues, F., Leite, V. A. P. H., Teixeira, M. R., & Bugalho, M. J. (2020) · Clinical Endocrinology · doi:10.1111/cen.14184 · Cited by 12

Use of monoclonal antibodies to detect specific mutations in formalin-fixed, paraffin-embedded tissue sections

Guo, Z., & Lloyd, R. V. (2016) · Human Pathology · doi:10.1016/j.humpath.2016.03.013 · Cited by 13

Inherited Neuroendocrine Neoplasms

Mete, Ö., Hannah‐Shmouni, F., Kim, R. H., & Stratakis, C. A. (2020) · Springer eBooks · doi:10.1007/978-3-030-54391-4_18 · Cited by 12

Mutation profiling in eight cases of vagal paragangliomas

Kudryavtseva, A. V., Kalinin, D. V., Pavlov, V., Savvateeva, M. V., Fedorova, M., Pudova, E. A., Kobelyatskaya, A. A., Golovyuk, A. L., Guvatova, Z. G., Razmakhaev, G. S., et al. (2020) · BMC Medical Genomics · doi:10.1186/s12920-020-00763-4 · Cited by 12

Detection of fetal subchromosomal aberration with cell-free DNA screening led to diagnosis of parental translocation: Review of 11344 consecutive cases in a university hospital

Qian, Y., Wang, X.-Q., Chen, M., Luo, Y.-Q., Yan, K., Yang, Y., Liu, B., Wang, L., Huang, Y., Li, H.-G., et al. (2018) · European Journal of Medical Genetics · doi:10.1016/j.ejmg.2018.06.012 · Cited by 11

Mutation screening in a Norwegian cohort with pheochromocytoma

Sjursen, W., Halvorsen, H., Hofsli, E., Bachke, S., Berge, Å., Engebretsen, L. F., Falkmer, S. E., Falkmer, S., & Varhaug, J. E. (2013) · Familial Cancer · doi:10.1007/s10689-013-9608-0 · Cited by 10

Succinate dehydrogenase mutations: paraganglioma imaging and at-risk population screening

Cavenagh, T., Patel, J., Nakhla, N., Elstob, A., Ingram, M. D., Barber, B. R., Snape, K. M. G., Bano, G., & Vlahos, I. (2018) · Clinical Radiology · doi:10.1016/j.crad.2018.11.004 · Cited by 10

Primary intrathyroidal paraganglioma: histopathology and novel molecular alterations

Costinean, S., Balatti, V., Bottoni, A., Old, M., Croce, C. M., & Wakely, P. E. (2012) · Human Pathology · doi:10.1016/j.humpath.2012.06.021 · Cited by 9

A Novel Human SDHA -Knockout Cell Line Model for the Functional Analysis of Clinically Relevant SDHA Variants

Kent, J. D., Klug, L. R., & Heinrich, M. C. (2024) · Clinical Cancer Research · doi:10.1158/1078-0432.ccr-24-1601 · Cited by 7

Unveiling the hidden role of SDHA in breast cancer proliferation: a novel therapeutic avenue

Yong, L., Fang, Y., Jin, L., Zhang, X., Luis, M. A., Lin, X., Tang, S., & Cai, F. (2025) · Cancer Cell International · doi:10.1186/s12935-025-03746-6 · Cited by 7

SDHA related phaeochromocytoma and paraganglioma: review and clinical management

Kaplan, A. I., Dwight, T., Luxford, C., Benn, D. E., & Clifton-Bligh, R. J. (2024) · Endocrine Related Cancer · doi:10.1530/erc-24-0111 · Cited by 7

An Update on the Histology of Pheochromocytomas: How Does it Relate to Genetics?

Oudijk, L., Gaal, J., Koopman, K., & de Krijger, R. R. (2018) · Hormone and Metabolic Research · doi:10.1055/a-0672-1266 · Cited by 7

Metastatic pheochromocytomas and paragangliomas: where are we?

Prinzi, N., Corti, F., Torchio, M., Niger, M., Antista, M., Pagani, F., Beninato, T., Pulice, I., Rossi, R. E., Coppa, J. C., et al. (2022) · Tumori Journal · doi:10.1177/03008916221078621 · Cited by 7

Clinical significance and peculiarities of succinate dehydrogenase B and hypoxia inducible factor 1α expression in parasympathetic versus sympathetic paragangliomas

Bernardo‐Castiñeira, C., Sáenz‐de‐Santa‐María, I., Valdés, N., Astudillo, A., Balbı́n, M., Pitiot, A. S., Jiménez‐Fonseca, P., Scola, B., Tena, I., Molina‐Garrido, M., et al. (2018) · Head & Neck · doi:10.1002/hed.25386 · Cited by 7

Management of Pheochromocytomas and Paragangliomas: A Case-Based Review of Clinical Aspects and Perspectives

Sobocki, B. K., Perdyan, A., Szot, O., & Rutkowski, J. (2022) · Journal of Clinical Medicine · doi:10.3390/jcm11092591 · Cited by 7

Impact of Surgical Resection for Subdiaphragmatic Paragangliomas

Abadin, S. S., Ayala‐Ramirez, M., Jiménez, C., Dickson, P. V., Liang, Y., Lazar, A. J., Hornick, J. L., Cotton, M., Sui, D., Rich, T. A., et al. (2014) · World Journal of Surgery · doi:10.1007/s00268-013-2443-5 · Cited by 7

Anatomy, physiology, and genetics of paragangliomas

Kim, Y., & Goldenberg, D. (2015) · Operative Techniques in Otolaryngology-Head and Neck Surgery · doi:10.1016/j.otot.2015.12.003 · Cited by 7

p.N78S and p.R161Q germline mutations of the VHL gene are present in von Hippel-Lindau syndrome in two pedigrees.

Qi, X.-P., Liu, W.-T., Li, J.-Y., Dai, Y.-J., Ma, J.-M., Zhao, Y., Fei, J., Li, F., Shen, M., Jin, H.-Y., et al. (2013) · Molecular Medicine Reports · doi:10.3892/mmr.2013.1578 · Cited by 7

Potential Pitfalls of SDH Immunohistochemical Detection in Paragangliomas and Phaeochromocytomas Harbouring Germline SDHx Gene Mutation

Santi, R., Rapizzi, E., Canu, L., Ercolino, T., Baroni, G., Fucci, R., COSTA, G., Mannelli, M., & Nesi, G. (2017) · Anticancer Research · doi:10.21873/anticanres.11381 · Cited by 35

An immunohistochemical procedure to detect patients with paraganglioma and phaeochromocytoma with germline SDHB, SDHC, or SDHD gene mutations: a retrospective and prospective analysis

van Nederveen, F. H., Gaal, J., Favier, J., Korpershoek, E., Oldenburg, R. A., de Bruyn, E. M., Sleddens, H. F. B. M., Derkx, P., Rivière, J., Dannenberg, H., et al. (2009) · The Lancet Oncology · doi:10.1016/s1470-2045(09)70164-0 · Cited by 554

SDHD Immunohistochemistry: A New Tool to ValidateSDHxMutations in Pheochromocytoma/Paraganglioma

Menara, M., Oudijk, L., Badoual, C., Bertherat, J. Y., Lussey‐Lepoutre, C., Amar, L., Iturrioz, X., Sibony, M., Zinzindohoué, F., de Krijger, R. R., et al. (2014) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2014-1870 · Cited by 55

Usefulness of Negative and Weak–Diffuse Pattern of SDHB Immunostaining in Assessment of SDH Mutations in Paragangliomas and Pheochromocytomas

Castelblanco, E., Santacana, M., Valls, J., Cubas, A. D., Cascón, A., Robledo, M., & Matías‐Guiu, X. (2013) · Endocrine Pathology · doi:10.1007/s12022-013-9269-4 · Cited by 51

Prevalence of succinate dehydrogenase deficiency in paragangliomas and phaeochromocytomas at a tertiary hospital in Cape Town: a retrospective review

Bruce‐Brand, C., & van Wyk, A. C. (2020) · Journal of Endocrinology Metabolism and Diabetes of South Africa · doi:10.1080/16089677.2020.1838161 · Cited by 5