Ketoconazole in Cushing's Disease: Is It Worth a Try?
Castinetti, Frederic, Guignat, Laurence, Giraud, Pauline, Muller, Marie, Kamenicky, Peter, Drui, Delphine, Caron, Philippe, Luca, Fiorina, Donadille, Bruno, Vantyghem, Marie Christine, Bihan, Helene, Delemer, Brigitte, Raverot, Gerald, Motte, Emmanuelle, Philippon, Melanie, Morange, Isabelle, Conte-Devolx, Bernard, Quinquis, Laurent, Martinie, Monique, Vezzosi, Delphine, Le Bras, Maelle, Baudry, Camille, Christin-Maitre, Sophie, Goichot, Bernard, Chanson, Philippe, Young, Jacques, Chabre, Olivier, Tabarin, Antoine, Bertherat, Jerome, Brue, Thierry·2014·The Journal of Clinical Endocrinology & Metabolism
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- Current and Emerging Medical Therapies in Pituitary TumorsNicolas Sahakian, Frédéric Castinetti, Thierry Christian Brue, Thomas Cuny · 2022 · Journal of Clinical Medicine
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- The Adrenal CortexPaul M. Stewart, John D C Newell-Price · 2016 · Elsevier eBooks
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- Low-dose etomidate for the management of severe hypercortisolaemia in different clinical scenarios: a case series and review of the literatureAgnieszka Łebek-Szatańska, Karolina M. Nowak, Wojciech Zgliczyński, Elżbieta Baum, Agnieszka Żyłka, Lucyna Papierska · 2019 · Therapeutic Advances in Endocrinology and Metabolism
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- Levoketoconazole: a novel treatment for endogenous Cushing's syndromeMaria Fleseriu, Richard Joseph Auchus, Rosario Pivonello, Roberto Salvatori, Sabina Zacharieva, Beverly M. K. Biller · 2021 · Expert Review of Endocrinology & Metabolism
- Safety and Efficacy of Subcutaneous Pasireotide in Patients With Cushing's Disease: Results From an Open-Label, Multicenter, Single-Arm, Multinational, Expanded-Access StudyMaria Fleseriu, Chioma Iweha, Luiz Roberto Salgado, Tânia Longo Mazzuco, Federico Campigotto, Ricardo Maamari, Padiporn Limumpornpetch · 2019 · Frontiers in Endocrinology
- Medical Management of Cushing DiseaseNicholas A. Tritos, Beverly M. K. Biller · 2019 · Neurosurgery Clinics of North America
- Posaconazole-Induced Adrenal Insufficiency in a Case of Chronic Myelomonocytic LeukemiaAnn J. Miller, Lauren K. Brooks, Silpa Poola-Kella, Rana Malek · 2018 · Case Reports in Endocrinology
- Ketoconazole as an Adrenal Steroidogenesis Inhibitor: Effectiveness and Risks in the Treatment of Cushing's DiseaseJohn D C Newell-Price · 2014 · The Journal of Clinical Endocrinology & Metabolism
- Update and Practical Recommendations for the Use of Medical Treatment of Cushing SyndromeMarta Araujo-Castro, Cristina Lamas, Elisabeth Nowak, John D C Newell-Price, Martín Reincke, Frédéric Castinetti · 2025 · Endocrine Reviews
- Current approaches to the pharmacological management of Cushing's diseaseMark E. Molitch · 2014 · Molecular and Cellular Endocrinology
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- Regulation of the EGFR Pathway by HSP90 Is Involved in the Pathogenesis of Cushing’s DiseaseYue Shen, Chenxing Ji, Xuemin Jian, Juan Zhou, Qilin Zhang, Nidan Qiao, Yichao Zhang, Xuefei Shou, Xiang Zhou, Zengyi Ma · 2021 · Frontiers in Endocrinology
- Repeat stereotactic radiosurgery for Cushing’s disease: outcomes of an international, multicenter studyGautam U. Mehta, D. Ding, Amitabh Gupta, H. Kano, Nathaniel D. Sisterson, N. Martínez-Moreno, M. Kršek, Huai-Che Yang, Cheng-Chia Lee, R. Liščák et al. · 2018 · Journal of Neuro-Oncology
- Emerging drugs for Cushing’s diseaseDaniela Guelho, Ashley Barry Grossman · 2015 · Expert Opinion on Emerging Drugs
- USP8: a novel therapeutic target for Cushing’s diseaseFangfang Jian, Yanan Cao, Liuguan Bian, Qingfang Sun · 2015 · Endocrine
- Dimethoxy-etomidate: A Nonhypnotic Etomidate Analog that Potently Inhibits SteroidogenesisMegan McGrath, Celena Ma, Douglas E. Raines · 2017 · Journal of Pharmacology and Experimental Therapeutics
- Italian Society for the Study of Diabetes (SID)/Italian Endocrinological Society (SIE) guidelines on the treatment of hyperglycemia in Cushing's syndrome and acromegalyMarco Giorgio Baroni, Francesco Giorgino, VINCENZO PEZZINO, Carla Maria Scaroni, Angelo Avogaro · 2016 · Nutrition Metabolism and Cardiovascular Diseases
- Current strategies for the treatment of severe Cushing’s syndromeKrystallenia Alexandraki, Ashley Barry Grossman · 2015 · Expert Review of Endocrinology & Metabolism
- Improvement in clinical features of hypercortisolism during osilodrostat treatment: findings from the Phase III LINC 3 trial in Cushing's diseaseRosario Pivonello, Maria Fleseriu, John D C Newell-Price, Akira Shimatsu, Richard Abraham Feelders, Pınar Kadıoğlu, Antoine Tabarin, Thierry Christian Brue, Eliza Brevoort Geer, A. Piacentini et al. · 2024 · Journal of Endocrinological Investigation
- Cardiometabolic complications after Cushing’s disease remissionIrene Tizianel, Laura Lizzul, Alessandro Mondin, Giacomo Voltan, Pierluigi Mazzeo, Carla Maria Scaroni, Mattia Barbot, Filippo Ceccato · 2025 · Journal of Endocrinological Investigation
- Medical combination therapies in Cushing’s diseaseLúcio Vilar, Luciana Ansaneli Naves, Márcio Carlos Machado, Marcello D. Bronstein · 2015 · Pituitary
- Medical treatment of Cushing’s disease with concurrent diabetes mellitusAnna Mehlich, Marek Bolanowski, Dawid Mehlich, Przemysław Witek · 2023 · Frontiers in Endocrinology
- Ketoconazole as second-line treatment for Cushing’s disease after transsphenoidal surgery: systematic review and meta-analysisCamila Viecceli, Ana Carolina Viana Mattos, Vânia Naomi Hirakata, Sheila Piccoli Garcia, Ticiana da Costa Rodrigues, Mauro Antônio Czepielewski · 2023 · Frontiers in Endocrinology
- A Case of Severe Psychosis Due to Cushing's Syndrome Secondary to Primary Bilateral Macronodular Adrenal HyperplasiaKajal Shah, Inderjit Mann, Kalpana Reddy, Geevarghese John · 2019 · Cureus
- No Untoward Effect of Long‐Term Ketoconazole Administration on Electrocardiographic QT Interval in Patients with Cushing's DiseaseMartina De Martin, Paola Maria Toja, Karine Goulene, Piero Radaelli, Francesco Cavagnini, Marco Stramba‐Badiale, Francesca Pecori Giraldi · 2015 · Basic & Clinical Pharmacology & Toxicology
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- The Role of Glucocorticoid Receptor in the Pathophysiology of Pituitary Corticotroph AdenomasDaniela Regazzo, Alessandro Mondin, Carla Maria Scaroni, Gianluca Occhi, Mattia Barbot · 2022 · International Journal of Molecular Sciences
- Management of Diabetes Mellitus in Acromegaly and Cushing’s Disease with Focus on Pasireotide Therapy: A Narrative ReviewMichelantonio De Fano, Alberto Falorni, Massimo Malara, Francesca Porcellati, Carmine Giuseppe Fanelli · 2024 · Diabetes Metabolic Syndrome and Obesity
- Ketoconazole- and Metyrapone-Induced Reductions on Urinary Steroid Metabolites Alter the Urinary Free Cortisol Immunoassay Reliability in Cushing SyndromeArturo Vega‐Beyhart, Javier Laguna, Daniela Díaz-Catalán, Laura Boswell, Mireia Mora, Irene Halperín, Gregori Casals, Felicia Alexandra Hanzu · 2022 · Frontiers in Endocrinology
- How best to monitor the specific side effects of medical treatments of Cushing’s diseaseFrédéric Castinetti · 2022 · Best Practice & Research Clinical Endocrinology & Metabolism
- Evaluation of Evidence of Adrenal Insufficiency in Trials of Normocortisolemic Patients Treated With MifepristoneKevin C.J. Yuen, Andreas G. Moraitis, Dat Nguyen · 2017 · Journal of the Endocrine Society
- Surgical Outcomes and Comorbidities in Cushing Disease: 30 Years of Experience in a Referral CenterAntonio Jesús Martínez-Ortega, Eva Maria Venegas-Moreno, Elena Dios, Pablo Remón-Ruiz, Javier Márquez-Rivas, Eugenio Cárdenas Ruiz‐Valdepeñas, Ariel Matias Kaen, David A. Cano, Alfonso Soto‐Moreno · 2018 · World Neurosurgery
- Fluconazole in the treatment of Cushing's diseaseKharis A. Burns, Darshika Christie‐David, Jenny Elizabeth Gunton · 2016 · Endocrinology Diabetes and Metabolism Case Reports
- Cushing’s Disease: Long-Term Effectiveness and Safety of Osilodrostat in a Polish Group of Patients with Persistent Hypercortisolemia in the Experience of a Single CenterŁukasz Działach, Joanna Sobolewska, Wioleta Respondek, Katarzyna Szamotulska, Przemysław Witek · 2023 · Biomedicines
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- New Insights in Cushing Disease Treatment With Focus on a Derivative of Vitamin AMariana Fuertes, Julieta Tkatch, Josefina Rosmino, Leandro Nieto, Mirtha Adriana Guitelman, EDUARDO S. ARZT · 2018 · Frontiers in Endocrinology
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- CYP24A1: structure, function, and physiological roleRené St‐Arnaud, Glenville Jones · 2023 · Elsevier eBooks
- A review of Cushing's disease treatment by the Department of Neuroendocrinology of the Brazilian Society of Endocrinology and MetabolismMárcio Carlos Machado, Maria Candida Barisson Villares Fragoso, Ayrton Custódio Moreira, César Luiz Boguszewski, Leonardo Vieira, Luciana Ansaneli Naves, Lúcio Vilar, Luiz Antônio de Araújo, Nina Rosa de Castro Musolino, Paulo Augusto Carvalho Miranda et al. · 2018 · Archives of Endocrinology and Metabolism
- Fluconazole as a Safe and Effective Alternative to Ketoconazole in Controlling Hypercortisolism of Recurrent Cushing’s Disease: A Case ReportShu Teng Chai, Amalina Haydar Ali Tajuddin, Norasyikin A Wahab, Norlaila Mustafa, Norlela Sukor, Nor Azmi Kamaruddin · 2018 · Intern J Endocrinol Metab
- Hypertension in Cushing’s SyndromeFilippo Ceccato, Mattia Barbot, Carla Maria Scaroni, Marco Boscaro · 2020 · Updates in hypertension and cardiovascular protection
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- Treatment of Cushing’s Syndrome : What Place for Medical Treatment?Olivier Chabre · 2019 · Acta Endocrinologica (Bucharest)
- Ectopic Corticotropin-Releasing Hormone/Adrenocorticotropic Hormone-Co-Secreting Neuroendocrine Tumors Leading to Cushing’s Disease: A Case Presentation and Literature ReviewJasmin Ewert, Maximilian Seidl, Jann Achim Hommen, Matthias Schott, Norbert Gattermann · 2025 · Neuroendocrinology
- Real-World Data on the Efficacy and Safety of Osilodrostat in Patients with Cushing’s Disease in SpainMarta Araujo Castro, Rogelio García-Centeno, Laura González Fernández, Felicia Alexandra Hanzu, Aida Orois, Rosa Cámara, María Dolores Ollero García, Ana Irigaray, Paola Gracia Gimeno, Eider Pascual Corrales et al. · 2025 · Journal of Clinical Medicine
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