The DOI matches its Crossref record.
Metabolic Effects of Short-Term Elevations of Plasma Cortisol Are More Pronounced in the Evening Than in the Morning
Abstract
To determine whether elevations of cortisol levels have more pronounced effects on glucose levels and insulin secretion in the evening (at the trough of the daily rhythm) or in the morning (at the peak of the rhythm), nine normal men each participated in four studies performed in random order. In all studies, endogenous cortisol levels were suppressed by metyrapone administration, and caloric intake was exclusively under the form of a constant glucose infusion. The daily cortisol elevation was restored by administration of hydrocortisone (or placebo) either at 0500 h or at 1700 h. In each study, plasma levels of glucose, insulin, C-peptide, and cortisol were measured at 20-min intervals for 32 h. The initial effect of the hydrocortisone-induced cortisol pulse was a short-term inhibition of insulin secretion without concomitant glucose changes and was similar in the evening and in the morning. At both times of day, starting 4-6 h after hydrocortisone ingestion, glucose levels increased and remained higher than under placebo for at least 12 h. This delayed hyperglycemic effect was minimal in the morning but much more pronounced in the evening, when it was associated with robust increases in serum insulin and insulin secretion and with a 30% decrease in insulin clearance. Thus, elevations of evening cortisol levels could contribute to alterations in glucose tolerance, insulin sensitivity, and insulin secretion.
Overview
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
Citations
Cited by
Sorted by citations
Allostasis and Allostatic Load Implications for Neuropsychopharmacology
McEwen, B. (2000) · Neuropsychopharmacology · doi:10.1016/s0893-133x(99)00129-3 · Cited by 1,833
Bornstein, S. R., Allolio, B., Arlt, W., Barthel, A., Don-Wauchope, A., Hammer, G. D., Husebye, E. S., Merke, D. P., Murad, M. H., Stratakis, C. A., et al. (2016) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2015-1710 · Cited by 1,769
Sleep loss: a novel risk factor for insulin resistance and type 2 diabetes
Spiegel, K., Knutson, K., Leproult, R., Tasali, E., & Cauter, E. V. (2005) · Journal of Applied Physiology · doi:10.1152/japplphysiol.00660.2005 · Cited by 1,175
Mood disorders and allostatic load
McEwen, B. S. (2003) · Biological Psychiatry · doi:10.1016/s0006-3223(03)00177-x · Cited by 1,135
Circadian regulation of glucose, lipid, and energy metabolism in humans
Poggiogalle, E., Jamshed, H., & Peterson, C. M. (2017) · Metabolism · doi:10.1016/j.metabol.2017.11.017 · Cited by 743
Congenital Adrenal Hyperplasia—Current Insights in Pathophysiology, Diagnostics, and Management
Claahsen - van der Grinten, H. L., Speiser, P. W., Ahmed, S. F., Arlt, W., Auchus, R. J., Falhammar, H., Flück, C. E., Guasti, L., Huebner, A., Kortmann, B. B. M., et al. (2022) · Endocrine Reviews · doi:10.1210/endrev/bnab016 · Cited by 556
The Functional and Clinical Significance of the 24-Hour Rhythm of Circulating Glucocorticoids
Oster, H., Challet, E., Ott, V., Arvat, E., de Kloet, E. R., Dijk, D.-J., Lightman, S., Vgontzas, A., & Van Cauter, E. (2017) · Endocrine Reviews · doi:10.1210/er.2015-1080 · Cited by 548
Diagnosis and management of adrenal insufficiency
Bancos, I., Hahner, S., Tomlinson, J., & Arlt, W. (2015) · The Lancet Diabetes & Endocrinology · doi:10.1016/s2213-8587(14)70142-1 · Cited by 467
Erichsen, M. M., Løvås, K., Skinningsrud, B., Wolff, A. B., Undlien, D. E., Svartberg, J., Fougner, K. J., Berg, T. J., Bollerslev, J., Mella, B., et al. (2009) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2009-1368 · Cited by 422
Husebye, E. S., Pearce, S. H., Krone, N. P., & Kämpe, O. (2021) · The Lancet · doi:10.1016/s0140-6736(21)00136-7 · Cited by 378
Modified-release hydrocortisone to provide circadian cortisol profiles
Debono, M., Ghobadi, C., Rostami-Hodjegan, A., Huatan, H., Campbell, M. J., Newell-Price, J., Darzy, K., Merke, D. P., Arlt, W., & Ross, R. J. (2009) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2008-2380 · Cited by 322
Reutrakul, S., & Van Cauter, E. (2014) · Annals of the New York Academy of Sciences · doi:10.1111/nyas.12355 · Cited by 321
The relationship between smoking status and cortisol secretion.
Badrick, E., Kirschbaum, C., & Kumari, M. (2007) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2006-2155 · Cited by 284
Role of sleep duration in the regulation of glucose metabolism and appetite
Morselli, L., Leproult, R., Balbo, M., & Spiegel, K. (2010) · Best Practice & Research Clinical Endocrinology & Metabolism · doi:10.1016/j.beem.2010.07.005 · Cited by 283
Higham, C., Johannsson, G., & Shalet, S. M. (2016) · The Lancet · doi:10.1016/s0140-6736(16)30053-8 · Cited by 273
Kumari, M., Badrick, E., Ferrie, J., Perski, A., Marmot, M., & Chandola, T. (2009) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2009-0555 · Cited by 229
Chronobiology in the endocrine system
Haus, E. L. (2007) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2007.01.001 · Cited by 228
Congenital adrenal hyperplasia
Auer, M. K., Nordenström, A., Lajić, S., & Reisch, N. (2022) · The Lancet · doi:10.1016/s0140-6736(22)01330-7 · Cited by 241
Isidori, A. M., Venneri, M. A., Graziadio, C., Simeoli, C., Fiore, D., Hasenmajer, V., Sbardella, E., Gianfrilli, D., Pozza, C., Pasqualetti, P., et al. (2018) · The Lancet Diabetes & Endocrinology · doi:10.1016/s2213-8587(17)30398-4 · Cited by 211
Morselli, L. L., Guyon, A., & Spiegel, K. (2012) · Pflügers Archiv - European Journal of Physiology · doi:10.1007/s00424-011-1053-z · Cited by 199
Raison, C. L., Borisov, A. S., Woolwine, B. J., Massung, B., Vogt, G., & Miller, A. H. (2010) · Molecular Psychiatry · doi:10.1038/mp.2008.58 · Cited by 183
The approach to the adult with newly diagnosed adrenal insufficiency
Arlt, W. (2009) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2009-0032 · Cited by 165
Association between Inadequate Sleep and Insulin Resistance in Obese Children
Flint, J. K., Kothare, S. V., Zihlif, M., Suarez, E. A., Adams, R., Legido, A., & Luca, F. D. (2007) · The Journal of Pediatrics · doi:10.1016/j.jpeds.2006.08.063 · Cited by 164
Kim, S., Lee, B.-R., Reeder, J. T., Seo, S. H., Lee, S.-U., Hourlier‐Fargette, A., Shin, J., Sekine, Y., Jeong, H., Oh, Y. S., et al. (2020) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2012700117 · Cited by 156
Sleep and circadian regulation of cortisol: A short review
O'Byrne, N. A., Yuen, F., Butt, W. Z., & Liu, P. Y. (2021) · Current Opinion in Endocrine and Metabolic Research · doi:10.1016/j.coemr.2021.03.011 · Cited by 145
The relationship between alcohol consumption and cortisol secretion in an aging cohort
Badrick, E., Bobak, M., Britton, A., Kirschbaum, C., Marmot, M., & Kumari, M. (2008) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2007-0737 · Cited by 143
Association of Short and Long Sleep Durations with Insulin Sensitivity in Adolescents
Javaheri, S., Storfer-Isser, A., Rosen, C. L., & Redline, S. (2011) · The Journal of Pediatrics · doi:10.1016/j.jpeds.2010.09.080 · Cited by 139
Impact of Sleep and Sleep Loss on Glucose Homeostasis and Appetite Regulation
Knutson, K. L. (2007) · Sleep Medicine Clinics · doi:10.1016/j.jsmc.2007.03.004 · Cited by 145
Inadequacies of glucocorticoid replacement and improvements by physiological circadian therapy
Debono, M., Ross, R. J. M., & Newell-Price, J. D. C. (2009) · European Journal of Endocrinology · doi:10.1530/eje-08-0874 · Cited by 140
Larcher, S., Benhamou, P., Pépin, J., & Borel, A. (2015) · Diabetes & Metabolism · doi:10.1016/j.diabet.2014.12.004 · Cited by 139
Guyon, A., Balbo, M., Morselli, L. L., Tasali, E., Leproult, R., L'Hermite-Balériaux, M., Van Cauter, E., & Spiegel, K. (2014) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2013-4254 · Cited by 127
Stavreva, D. A., Garcia, D. A., Fettweis, G., Gudla, P. R., Zaki, G., Soni, V., McGowan, A., Williams, G. L., Huynh, A., Palangat, M., et al. (2019) · Molecular Cell · doi:10.1016/j.molcel.2019.06.042 · Cited by 123
Quinkler, M. O., Nilsen, R. M., Zopf, K., Ventz, M., & Øksnes, M. (2015) · European Journal of Endocrinology · doi:10.1530/eje-14-1114 · Cited by 127
Inadequate Sleep as a Contributor to Obesity and Type 2 Diabetes
McNeil, J., Doucet, É., & Chaput, J. (2013) · Canadian Journal of Diabetes · doi:10.1016/j.jcjd.2013.02.060 · Cited by 127
Whitaker, M. J., Debono, M., Huatan, H., Merke, D. P., Arlt, W., & Ross, R. J. (2014) · Clinical Endocrinology · doi:10.1111/cen.12316 · Cited by 121
Adrenal insufficiency: review of clinical outcomes with current glucocorticoid replacement therapy
Johannsson, G., Falorni, A., Skrtic, S., Lennernäs, H., Quinkler, M., Monson, J. P., & Stewart, P. M. (2015) · Clinical Endocrinology · doi:10.1111/cen.12603 · Cited by 122
Grossman, A., Johannsson, G., Quinkler, M., & Zelissen, P. (2013) · European Journal of Endocrinology · doi:10.1530/eje-13-0450 · Cited by 119
Killick, R., Hoyos, C. M., Melehan, K. L., Dungan, G. C., Poh, J., & Liu, P. Y. (2015) · Clinical Endocrinology · doi:10.1111/cen.12747 · Cited by 108
An Update on Addison’s Disease
Barthel, A., Benker, G., Berens, K., Diederich, S., Manfras, B. J., Grüber, M., Kanczkowski, W., Kline, G. A., Kamvissi, V., Hahner, S., et al. (2018) · Experimental and Clinical Endocrinology & Diabetes · doi:10.1055/a-0804-2715 · Cited by 115
Duclos, M., Gatta‐Cherifi, B., Corcuff, J., Rashedi, M., Péhourcq, F., & Roger, P. (2001) · Clinical Endocrinology · doi:10.1046/j.1365-2265.2001.01384.x · Cited by 104
Treatment and health outcomes in adults with congenital adrenal hyperplasia
Han, T. S., Walker, B. R., Arlt, W., & Ross, R. J. (2014) · Nature Reviews Endocrinology · doi:10.1038/nrendo.2013.239 · Cited by 102
Impact of age, sex and body mass index on cortisol secretion in 143 healthy adults
Roelfsema, F., van Heemst, D., Iranmanesh, A., Takahashi, P., Yang, R., & Veldhuis, J. D. (2017) · Endocrine Connections · doi:10.1530/ec-17-0160 · Cited by 100
Debono, M., Harrison, R. F., Chadarevian, R., Gueroult, C., Abitbol, J.-L., & Newell-Price, J. (2017) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2017-00823 · Cited by 100
Mazziotti, G., Formenti, A. M., Frara, S., Roca, E., Mortini, P., Berruti, A., & Giustina, A. (2017) · European Journal of Endocrinology · doi:10.1530/eje-17-0154 · Cited by 96
Exploring inpatient hospitalizations and morbidity in patients with adrenal insufficiency
Stewart, P. M., Biller, B. M. K., Marelli, C., Gunnarsson, C., Ryan, M. P., & Johannsson, G. (2016) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2016-2221 · Cited by 90
Modified-Release Hydrocortisone in Congenital Adrenal Hyperplasia
Merke, D. P., Mallappa, A., Arlt, W., Brac de la Perriere, A., Lindén Hirschberg, A., Juul, A., Newell-Price, J., Perry, C. G., Prete, A., Rees, D. A., et al. (2021) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/clinem/dgab051 · Cited by 109
Joseph, N. T., Jiang, Y., & Zilioli, S. (2021) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2021.02.042 · Cited by 89
Sleep, testosterone and cortisol balance, and ageing men
Liu, P. Y., & Reddy, R. T. (2022) · Reviews in Endocrine and Metabolic Disorders · doi:10.1007/s11154-022-09755-4 · Cited by 80
Venneri, M. A., Hasenmajer, V., Fiore, D., Sbardella, E., Pofi, R., Graziadio, C., Gianfrilli, D., Pivonello, C., Negri, M., Naro, F., et al. (2018) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2018-00346 · Cited by 82
The influence of sleep and sleep loss upon food intake and metabolism
Crispim, C. A., Zimberg, I. Z., Dattilo, M., Padilha, H. G., Edwards, B., Waterhouse, J. M., Tufik, S., & de Mello, M. T. (2007) · Nutrition Research Reviews · doi:10.1017/s0954422407810651 · Cited by 80
Circadian regulation of metabolic homeostasis: causes and consequences
Young, M. E., & McGinnis, G. R. (2016) · Nature and Science of Sleep · doi:10.2147/nss.s78946 · Cited by 82
Ajabnoor, G., Bahijri, S., Borai, A., Abdulkhaliq, A. A., Al-Aama, J. Y., & Chrousos, G. P. (2014) · PLoS ONE · doi:10.1371/journal.pone.0096500 · Cited by 80
Human studies on hypothalamo-pituitary-adrenal (HPA) axis
Liyanarachchi, K., Ross, R. J. M., & Debono, M. (2017) · Best Practice & Research Clinical Endocrinology & Metabolism · doi:10.1016/j.beem.2017.10.011 · Cited by 83
Branth, S., Ronquist, G., Stridsberg, M., Hambræus, L., Kindgren, E., Olsson, R., Carlander, D., & Arnetz, B. B. (2006) · Nutrition Metabolism and Cardiovascular Diseases · doi:10.1016/j.numecd.2006.03.001 · Cited by 71
Glucocorticoid treatment regimen and health outcomes in adults with congenital adrenal hyperplasia
Han, T. S., Stimson, R. H., Rees, D. A., Krone, N., Willis, D. S., Conway, G. S., Arlt, W., Walker, B. R., Ross, R. J., & (CaHASE), U. K. C. A. H. A. S. E. (2013) · Clinical Endocrinology · doi:10.1111/cen.12045 · Cited by 70
Metyrapone treatment in Cushing’s syndrome: a real-life study
Ceccato, F., Zilio, M., Barbot, M., Albiger, N. M. E., Antonelli, G., Plebani, M., Watutantrige‐Fernando, S., Sabbadin, C., Boscaro, M., & Scaroni, C. M. (2018) · Endocrine · doi:10.1007/s12020-018-1675-4 · Cited by 69
Mocking, R. J. T., Ruhé, H. G., Assies, J., Lok, A., Koeter, M. W. J., Visser, I., Bockting, C., & Schene, A. H. (2013) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2013.01.013 · Cited by 68
Bensing, S., Hulting, A., Husebye, E. S., Kämpe, O., & Løvås, K. (2016) · European Journal of Endocrinology · doi:10.1530/eje-15-1242 · Cited by 71
Cortisol and GH: odd and controversial ideas
Duclos, M., Guinot, M., & Bouc, Y. L. (2007) · Applied Physiology, Nutrition, and Metabolism · doi:10.1139/h07-064 · Cited by 66
Glycemic control is impaired in the evening in prediabetes through multiple diurnal rhythms
Sonnier, T. J., Rood, J., Gimble, J. M., & Peterson, C. M. (2014) · Journal of Diabetes and its Complications · doi:10.1016/j.jdiacomp.2014.04.001 · Cited by 62
Autonomic dysregulation and sleep homeostasis in insomnia
Grimaldi, D., Reid, K. J., Papalambros, N. A., Braun, R., Malkani, R. G., Abbott, S. M., Ong, J. C., & Zee, P. C. (2020) · SLEEP · doi:10.1093/sleep/zsaa274 · Cited by 60
Adrenal Cortical Insufficiency
Quinkler, M. O., Beuschlein, F., Hahner, S., Meyer, G., Schöfl, C., & Stalla, G. K. (2013) · Deutsches Ärzteblatt international · doi:10.3238/arztebl.2013.0882 · Cited by 69
Seelig, E., Keller, U. B., Klarhöfer, M., Scheffler, K., Brand, S., Holsboer‐Trachsler, E., Hatzinger, M., & Bilz, S. (2013) · PLoS ONE · doi:10.1371/journal.pone.0061780 · Cited by 61
Murray, R. D., Ekman, B., Uddin, S., Marelli, C., Quinkler, M. O., ZELISSEN, P. M. J., & the EU-AIR Investigators (2016) · Clinical Endocrinology · doi:10.1111/cen.13267 · Cited by 63
Pediatric Adrenal Insufficiency: Diagnosis, Management, and New Therapies
Bowden, S. A., & Henry, R. K. (2018) · International Journal of Pediatrics · doi:10.1155/2018/1739831 · Cited by 62
Perogamvros, I., Vassiliadi, D. A., Karapanou, O., Botoula, E., Tzanela, M., & Tsagarakis, S. (2015) · European Journal of Endocrinology · doi:10.1530/eje-15-0566 · Cited by 57
Saverino, S., & Falorni, A. (2020) · Best Practice & Research Clinical Endocrinology & Metabolism · doi:10.1016/j.beem.2020.101379 · Cited by 61
Substance Use and Women's Health
Kay, A. L., Taylor, T., Barthwell, A. G., Wichelecki, J., & Leopold, V. (2010) · Journal of Addictive Diseases · doi:10.1080/10550881003684640 · Cited by 51
Sorgdrager, F. J. H., Doornbos, B., Penninx, B. W. J. H., de Jonge, P., & Kema, I. P. (2017) · Journal of Affective Disorders · doi:10.1016/j.jad.2017.06.052 · Cited by 49
Schmoller, A., Eberhardt, F., Jauch-Chara, K., Schweiger, U., Zabel, P., Peters, A., Schultes, B., & Oltmanns, K. (2009) · Metabolism: Clinical and Experimental · doi:10.1016/j.metabol.2009.02.014 · Cited by 43
Sleep and Hormonal Changes in Aging
Copinschi, G., & Caufriez, A. (2013) · Endocrinology and Metabolism Clinics of North America · doi:10.1016/j.ecl.2013.02.009 · Cited by 43
Björnsdóttir, S., Øksnes, M., Isaksson, M., Methlie, P., Nilsen, R. M., Hustad, S., Kämpe, O., Hulting, A., Husebye, E. S., Løvås, K., et al. (2014) · Clinical Endocrinology · doi:10.1111/cen.12670 · Cited by 44
Short-term moderate sleep restriction decreases insulin sensitivity in young healthy adults
Wang, X., Greer, J., Porter, R. R., Kaur, K., & Youngstedt, S. D. (2016) · Sleep Health · doi:10.1016/j.sleh.2015.11.004 · Cited by 42
Neuroendocrine Regulation of Sleep Disturbances in PTSD
Neylan, T. C., Otte, C., Yehuda, R., & Marmar, C. R. (2006) · Annals of the New York Academy of Sciences · doi:10.1196/annals.1364.015 · Cited by 39
Ranjit, N., Diez-Roux, A., Sánchez, B. N., Seeman, T., Shea, S., Shrager, S., & Watson, K. (2009) · Psychosomatic Medicine · doi:10.1097/psy.0b013e3181ad23e7 · Cited by 44
Nilsson, A. G., Bergthorsdottir, R., Burman, P., Dahlqvist, P. M., Ekman, B., Engström, B. E., Ragnarsson, Ó., Skrtic, S., Wahlberg, J., Achenbach, H., et al. (2017) · European Journal of Endocrinology · doi:10.1530/eje-17-0067 · Cited by 40
The difficulties of pseudo-Cushing's syndrome (or “non-neoplastic hypercortisolism”)
Chabre, O. (2018) · Annales d Endocrinologie · doi:10.1016/j.ando.2018.04.017 · Cited by 39
Reutrakul, S., Crowley, S. J., Park, J. C., Chau, F. Y., Priyadarshini, M., Hanlon, E. C., Danielson, K. K., Gerber, B. S., Baynard, T., Yeh, J. J., et al. (2020) · Scientific Reports · doi:10.1038/s41598-020-58205-1 · Cited by 38
Fine tuning for quality of life: 21st century approach to treatment of Addison’s disease
Reisch, N., & Arlt, W. (2009) · Endocrinology and Metabolism Clinics of North America · doi:10.1016/j.ecl.2009.01.008 · Cited by 36
Elbelt, U., Hahner, S., & Allolio, B. (2009) · European Journal of Endocrinology · doi:10.1530/eje-08-1003 · Cited by 37
Bulcun, E., Ekici, M. S., & Ekici, A. B. (2011) · International Journal of Clinical Practice · doi:10.1111/j.1742-1241.2011.02795.x · Cited by 35
Effects of Insufficient Sleep on Pituitary–Adrenocortical Response to CRH Stimulation in Healthy Men
Guyon, A., Morselli, L. L., Balbo, M. L., Tasali, E., Leproult, R., L’Hermite-Balériaux, M., Van Cauter, E., & Spiegel, K. (2017) · SLEEP · doi:10.1093/sleep/zsx064 · Cited by 35
Sawamoto, R., Nozaki, T., Furukawa, T., Tanahashi, T., Morita, C., Hata, T., Komaki, G., & Sudo, N. (2014) · Nutrition and Diabetes · doi:10.1038/nutd.2014.41 · Cited by 34
Iatrogenic adrenal insufficiency in adults
Martin‐Grace, J., Tomkins, M., O’Reilly, M., & Sherlock, M. (2024) · Nature Reviews Endocrinology · doi:10.1038/s41574-023-00929-x · Cited by 35
Božić, J., Galić, T., Šupe‐Domić, D., Ivković, N., Kurir, T. T., Valić, Z., Lesko, J., & Đogaš, Z. (2016) · Endocrine · doi:10.1007/s12020-016-0925-6 · Cited by 36
Optimal glucocorticoid replacement in adrenal insufficiency
Øksnes, M., Ross, R. J. M., & Løvås, K. (2014) · Best Practice & Research Clinical Endocrinology & Metabolism · doi:10.1016/j.beem.2014.09.009 · Cited by 31
Response to commentaries on the concept of allostasis
McEwen, B. S., & Wingfield, J. C. (2003) · Hormones and Behavior · doi:10.1016/s0018-506x(02)00039-9 · Cited by 32
Oda, S., Ashida, K., Uchiyama, M., Sakamoto, S., Hasuzawa, N., Nagayama, A., Wang, L., Nagata, H., Sakamoto, R., Kishimoto, J., et al. (2021) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/clinem/dgab450 · Cited by 32
Sarafoglou, K., Merke, D. P., Reisch, N., der Grinten, H. L. C., Falhammar, H., & Auchus, R. J. (2023) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/clinem/dgad134 · Cited by 32
A link between sleep loss, glucose metabolism and adipokines
Padilha, H. G., Crispim, C. A., Zimberg, I. Z., De-Souza, D. A., Waterhouse, J. M., Tufik, S., & de-Mello, M. T. (2011) · Brazilian Journal of Medical and Biological Research · doi:10.1590/s0100-879x2011007500113 · Cited by 33
Kumari, S., Mittal, A., & Dabur, R. (2016) · Steroids · doi:10.1016/j.steroids.2016.03.016 · Cited by 31
Borresen, S. W., Thorgrimsen, T. B., Jensen, B., Hilsted, L., Bartels, E. M., Feldt‐Rasmussen, U., & Locht, H. (2020) · Rheumatology · doi:10.1093/rheumatology/keaa011 · Cited by 30
Hartaigh, B. Ó., Loerbroks, A., Thomas, G. N., Engeland, C. G., Hollands, M. A., Fischer, J. E., & Bosch, J. A. (2011) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2011.10.009 · Cited by 29
Factors impacting on the action of glucocorticoids in patients receiving glucocorticoid therapy
Dineen, R., Stewart, P. M., & Sherlock, M. (2019) · Clinical Endocrinology · doi:10.1111/cen.13837 · Cited by 30
Diurnal Regulation of Peripheral Glucose Metabolism: Potential Effects of Exercise Timing
Mancilla, R., Krook, A., Schrauwen, P., & Hesselink, M. K. C. (2020) · Obesity · doi:10.1002/oby.22811 · Cited by 29
Improved salivary cortisol rhythm with dual-release hydrocortisone
Ceccato, F., Selmin, E., Sabbadin, C., Costa, M. D., Antonelli, G., Plebani, M., Barbot, M., Betterle, C., Boscaro, M., & Scaroni, C. M. (2018) · Endocrine Connections · doi:10.1530/ec-18-0257 · Cited by 29
Modified-Release Hydrocortisone: Is It Time to Change Clinical Practice?
Stewart, P. M. (2019) · Journal of the Endocrine Society · doi:10.1210/js.2019-00046 · Cited by 29
Torres‐Farfan, C., Valenzuela, F. J., Ebensperger, R., Méndez, N., Campino, C., Richter, H. G., Valenzuela, G. J., & Serón‐Ferré, M. (2007) · American Journal of Primatology · doi:10.1002/ajp.20461 · Cited by 28
Maguire, A. M., Ambler, G. R., Moore, B., McLean, M., Falleti, M. G., & Cowell, C. T. (2007) · Pediatrics · doi:10.1542/peds.2006-2558 · Cited by 27
Liu, P. Y., Lawrence-Sidebottom, D., Piotrowska, K., Zhang, W., Iranmanesh, A., Auchus, R. J., Veldhuis, J. D., & Van Dongen, H. P. A. (2021) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/clinem/dgab375 · Cited by 28
Metadata
- Authors
- Plat, L.
- Venue
- Journal of Clinical Endocrinology & Metabolism
- Publisher
- The Endocrine Society
- Published
- 1999-09-01
- Volume
- 84
- Issue
- 9
- Pages
- 3082-3092
- ISSN
- 0021-972X (ISSN-L)
- OpenAlex
- W4250515708
- Cited by
- 177
- References
- 0
- Citations by year
- 2026: 2 · 2025: 2 · 2024: 9 · 2023: 6 · 2022: 8 · 2021: 8 · 2020: 12 · 2019: 4 · 2018: 13 · 2017: 13 · 2016: 13 · 2015: 8 · 2014: 11 · 2013: 12 · 2012: 5
- FWCI
- 2.78
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- The Journal of Clinical Endocrinology & Metabolism (publishedVersion)
- Dépôt institutionnel de l'Université libre de Bruxelles (Université Libre de Bruxelles) (submittedVersion)
- Topics
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Adrenal Hormones and Disorders
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Pancreatic function and diabetes
- Life Sciences › Neuroscience › Behavioral Neuroscience › Stress Responses and Cortisol
- Keywords
- cortisol, circadian rhythm, metyrapone, insulin secretion, glucose tolerance, hyperglycemia, insulin clearance, C-peptide, glucose infusion, time of day, insulin sensitivity
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
