The DOI matches its Crossref record.
Coated Charcoal Immunoassay of Insulin
Abstract
Charcoal premixed with dextran of average molecular weight 80,000 almost instantly adsorbs free insulin but rejects antibody-bound insulin. The use of such dextran-coated charcoal makes simpler and more rapid the immunoassay of insulin in biologic fluids, using radioisotope dilution with 131I-insulin and “biopsy” of the insulin pool by antibody to insulin. The procedure here described yields a straight line graph when insulin added is plotted against insulin recovered.
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Citations
Cited by
O'Leary, D. H., Polak, J. F., Kronmal, R. A., Manolio, T. A., Burke, G. L., & Wolfson, S. K. (1999) · New England Journal of Medicine · doi:10.1056/nejm199901073400103 · Cited by 4,685
Weyer, C., Bogardus, C., Mott, D. M., & Pratley, R. E. (1999) · Journal of Clinical Investigation · doi:10.1172/jci7231 · Cited by 1,940
Quantitative estimation of insulin sensitivity.
Bergman, R. N., Ider, Y. Z., Bowden, C. R., & Cobelli, C. (1979) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.1979.236.6.e667 · Cited by 1,874
Menopause and Risk Factors for Coronary Heart Disease
Matthews, K. A., Meilahn, E., Kuller, L. H., Kelsey, S. F., Caggiula, A. W., & Wing, R. R. (1989) · New England Journal of Medicine · doi:10.1056/nejm198909073211004 · Cited by 1,040
Studies of pancreatic alpha cell function in normal and diabetic subjects
Unger, R. H., Aguilar-Parada, E., Müller, W. A., & Eisentraut, A. M. (1970) · Journal of Clinical Investigation · doi:10.1172/jci106297 · Cited by 837
Metadata
- Authors
- HERBERT, V., LAU, K.-S., GOTTLIEB, C. W., & BLEICHER, S. J.
- Venue
- The Journal of Clinical Endocrinology & Metabolism
- Publisher
- The Endocrine Society
- Published
- 1965-10
- Volume
- 25
- Issue
- 10
- Pages
- 1375-1384
- ISSN
- 0021-972X (ISSN-L)
- 1945-7197
- OpenAlex
- W2078073869
- Cited by
- 2,968
- References
- 0
- FWCI
- 72.05
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: Coated Charcoal Immunoassay of Insulin. https://app.cochat.ai/papers/10.1210/jcem-25-10-1375
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- HERBERT, V., LAU, K.-S., GOTTLIEB, C. W., & BLEICHER, S. J. (1965). Coated Charcoal Immunoassay of Insulin. The Journal of Clinical Endocrinology & Metabolism. https://doi.org/10.1210/jcem-25-10-1375
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
