Cited by 199Pituitary Gland Disorders and TreatmentsGrowth Hormone and Insulin-like Growth FactorsHypothalamic control of reproductive hormones

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DOPAMINE INFUSION ACUTELY INHIBITS THE TSH AND PROLACTIN RESPONSE TO TRH

Besses, G. S., Burrow, G. N., Spaulding, S. W., Donabedian, R. K., Pechinski, T.·1975·The Journal of Clinical Endocrinology & Metabolism

DOI 10.1210/jcem-41-5-985

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Abstract

Ten normal males were given 100 mug TRH, and blood samples obtained for serum TSH and serum prolactin. After a period of at least one week, the TRH test was repeated while the patients were receiving a dopamine infusion. Both the TSH and prolactin response to TRH were inhibited by dopamine. Dopaminergic neurons may act through the pituitary-portal system to play a role in the regulation of TSH and prolactin secretion.

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Authors: Besses, G. S., Burrow, G. N., Spaulding, S. W., Donabedian, R. K., & Pechinski, T.
Affiliations: Yale University (US)
Venue: The Journal of Clinical Endocrinology & Metabolism
Publisher: The Endocrine Society
Published: 1975-11
Volume: 41
Issue: 5
Pages: 985-988
ISSN: 0021-972X (ISSN-L)
1945-7197
DOI: 10.1210/jcem-41-5-985
OpenAlex: W2080277814
Cited by: 199
References: 0
Citations by year: 2024: 3 · 2023: 1 · 2022: 1 · 2020: 1 · 2018: 1 · 2017: 1 · 2016: 2 · 2013: 1 · 2012: 2
FWCI: 14.31
Type: journal article
Language: en
Open access: closed
Locations: The Journal of Clinical Endocrinology & Metabolism (publishedVersion)
PubMed (publishedVersion)
Topics: Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Pituitary Gland Disorders and Treatments
Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Growth Hormone and Insulin-like Growth Factors
Health Sciences › Medicine › Reproductive Medicine › Hypothalamic control of reproductive hormones
Keywords: dopamine, thyrotropin-releasing hormone, thyroid-stimulating hormone, prolactin, TSH secretion, prolactin secretion, dopaminergic neurons, hypothalamic-pituitary-thyroid axis
MeSH terms: Adult, Depression, Chemical, Dopamine, Humans, Male, Prolactin, Thyrotropin, Thyrotropin-Releasing Hormone

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DOPAMINE INFUSION ACUTELY INHIBITS THE TSH AND PROLACTIN RESPONSE TO TRH

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