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Cited by 296

The DOI matches its Crossref record; 9 of the 9 references it cites were found in a registry or an index.

Treatment of Male Hypogonadism with Testosterone Enanthate*

SNYDER, PETER J., LAWRENCE, DAVID A.·1980·The Journal of Clinical Endocrinology & Metabolism
DOI 10.1210/jcem-51-6-1335
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Abstract

To determine the relative efficacy of several dosage regimens of testosterone enanthate in the treatment of male hypogonadism, we treated men who had primary hypogonadism with the following dosage regimens: 100 mg once a week, 200 mg every 2 weeks, 300 mg every 3 weeks, and 400 mg every 4 weeks, each for 12--16 weeks. Twenty-three men completed 37 dosage regimens. The 100-, 200-, and 300-mg dosages all suppressed the initially elevated serum LH concentrations to normal, but the 400-mg dosage did not. The 100- and 200-mg regimens suppressed the initially elevated serum FSH concentrations to normal, and the 300-mg regimen almost did not so. All four regimens produced serum testosterone concentrations that fluctuated largely within the normal range, the average concentration between doses was highest with 100 mg and lowest with 400 mg. The regimens of 200 mg every 2 weeks and 300 mg every 3 weeks appeared to be the most effective of those tested in terms of suppression of the serum LH concentration to normal and infrequency of administration. The close parallel of the FSH response to that of LH suggests that testosterone is the major physiological inhibitor of FSH as well as of LH.

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Metadata

Authors
SNYDER, P. J., & LAWRENCE, D. A.
Venue
The Journal of Clinical Endocrinology & Metabolism
Publisher
The Endocrine Society
Published
1980-12
Volume
51
Issue
6
Pages
1335-1339
ISSN
  • 0021-972X (ISSN-L)
  • 1945-7197
DOI
10.1210/jcem-51-6-1335
OpenAlex
W2057233158
Cited by
296
References
9
FWCI
1.50
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Treatment of Male Hypogonadism with Testosterone Enanthate*. https://app.cochat.ai/papers/10.1210/jcem-51-6-1335
The paper
SNYDER, P. J., & LAWRENCE, D. A. (1980). Treatment of Male Hypogonadism with Testosterone Enanthate*. The Journal of Clinical Endocrinology & Metabolism. https://doi.org/10.1210/jcem-51-6-1335

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.