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Cited by 202

The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.

CORTICOTROPIN-RELEASING FACTOR-LIKE ACTIVITY IN HUMAN PLACENTAL EXTRACTS

Shibasaki, Tamotsu, Odagiri, Emi, Shizume, Kazuo, Ling, Nicholas·1982·The Journal of Clinical Endocrinology & Metabolism

Abstract

Corticotropin-releasing factor (C R F)-like activity, which was first found in the hypothalamus, was detected in the extracts of human placentas obtained at full term from spontaneous deliveries. The molecular size of the placental CRF-like substance is slightly larger than that of adrenocorticotropin. In cultures of rat anterior pituitary cells, the placental CRF-like material shows bioactivity similar to that of the partially purified rat hypothalamic CRF and synthetic ovine C R F on the release of adrenocorticotropin and (β-endorphin. Furthermore, the CRF-like activity from human placenta was attenuated by trypsin digestion. Thus the human placenta may elaborate a substance similar to hypothalamic CRF.

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Metadata

Authors
Shibasaki, T., Odagiri, E., Shizume, K., & Ling, N.
Venue
The Journal of Clinical Endocrinology & Metabolism
Published
1982-08
Volume
55
Issue
2
Pages
384-386
ISSN
  • 0021-972X (ISSN-L)
  • 1945-7197
OpenAlex
W2030000366
Cited by
202
References
1
FWCI
0.93
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: CORTICOTROPIN-RELEASING FACTOR-LIKE ACTIVITY IN HUMAN PLACENTAL EXTRACTS. https://app.cochat.ai/papers/10.1210/jcem-55-2-384
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Shibasaki, T., Odagiri, E., Shizume, K., & Ling, N. (1982). CORTICOTROPIN-RELEASING FACTOR-LIKE ACTIVITY IN HUMAN PLACENTAL EXTRACTS. The Journal of Clinical Endocrinology & Metabolism. https://doi.org/10.1210/jcem-55-2-384

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