The DOI matches its Crossref record.
SPECIFIC HIGH-AFFINITY RECEPTORS FOR 1,25-DIHYDROXYVITAMIN D3IN HUMAN PERIPHERAL BLOOD MONONUCLEAR CELLS: PRESENCE IN MONOCYTES AND INDUCTION IN T LYMPHOCYTES FOLLOWING ACTIVATION
Abstract
Human peripheral blood monocytes have high affinity binding sites for 1,25-(OH)2D3 (Kd 0.14 nM, sedimentation coefficient 3.7S). Resting human peripheral blood T lymphocytes, however, do not have a demonstrable 1,25-(OH)2D3 receptor. After activation with phytohemagglutinin the T cells exhibit the receptor within 24 h, and this expression is blocked by cycloheximide. The receptor in activated T lymphocytes has a sedimentation coefficient of 3.7S and a high affinity (Kd 0.10 nM) for the ligand.
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Cited by
Yamshchikov, A. V., Desai, N. S., Blumberg, H. M., Ziegler, T. R., & Tangpricha, V. (2009) · Endocrine Practice · doi:10.4158/ep09101.orr · Cited by 307
Higher serum vitamin D concentrations are associated with longer leukocyte telomere length in women
Richards, J. B., Valdes, A. M., Gardner, J. P., Paximadas, D., Kimura, M., Nessa, A., Lu, X., Surdulescu, G. L., Swaminathan, R., Spector, T. D., et al. (2007) · The American Journal of Clinical Nutrition · doi:10.1093/ajcn/86.5.1420 · Cited by 237
Wang, Y., Zheng, J., Islam, M. S., Yang, Y., Hu, Y., & Chen, X. (2021) · International Journal of Biological Sciences · doi:10.7150/ijbs.59534 · Cited by 71
Metadata
- Authors
- BHALLA, A. K., AMENTO, E. P., CLEMENS, T. L., HOLICK, M. F., & KRANE, S. M.
- Venue
- The Journal of Clinical Endocrinology & Metabolism
- Publisher
- The Endocrine Society
- Published
- 1983-12
- Volume
- 57
- Issue
- 6
- Pages
- 1308-1310
- ISSN
- 0021-972X (ISSN-L)
- 1945-7197
- OpenAlex
- W1988738875
- Cited by
- 605
- References
- 0
- FWCI
- 12.21
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: SPECIFIC HIGH-AFFINITY RECEPTORS FOR 1,25-DIHYDROXYVITAMIN D3IN HUMAN PERIPHERAL BLOOD MONONUCLEAR CELLS: PRESENCE IN MONOCYTES AND INDUCTION IN T LYMPHOCYTES FOLLOWING ACTIVATION. https://app.cochat.ai/papers/10.1210/jcem-57-6-1308
- The paper
- BHALLA, A. K., AMENTO, E. P., CLEMENS, T. L., HOLICK, M. F., & KRANE, S. M. (1983). SPECIFIC HIGH-AFFINITY RECEPTORS FOR 1,25-DIHYDROXYVITAMIN D3IN HUMAN PERIPHERAL BLOOD MONONUCLEAR CELLS: PRESENCE IN MONOCYTES AND INDUCTION IN T LYMPHOCYTES FOLLOWING ACTIVATION. The Journal of Clinical Endocrinology & Metabolism. https://doi.org/10.1210/jcem-57-6-1308
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.