Cited by 100Hypothalamic control of reproductive hormonesOvarian function and disordersReproductive Physiology in Livestock

HORMONAL FACTORS INVOLVED IN THE REGULATION OF BASAL BODY TEMPERATURE DURING THE MENSTRUAL CYCLE AND PREGNANCY*

BUXTON, CHARLES L., ATKINSON, WILLIAM B.·1948·The Journal of Clinical Endocrinology & Metabolism

Abstract

THE biphasic aspect of the basal body temperature during the normal menstrual cycle is now a well-established fact. The temperature rise of three-fifths to one degree Fahrenheit which occurs at or about the time of ovulation is a phenomenon frequently used diagnostically and therapeutically. There are frequent variations from this typical biphasic curve, with its abrupt midcycle rise, which have been commented upon elsewhere (1), but generally speaking the rise maintains itself until the onset of the next menstrual period during which it drops to its preovulatory level. In the event that pregnancy occurs and the next menstrual period fails to appear when expected, the basal temperature does not return to its preovulatory level, but continues at or about the level maintained during the latter two weeks of the menstrual cycle. This, in itself, is a fairly accurate diagnostic sign of pregnancy. The purpose of this paper is two-fold: first, to present evidence as to the actual cause of the temperature rise during the latter half of the menstrual cycle and second, to investigate the progress of the basal body temperature throughout pregnancy.

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Crossref · 10.1210/jcem-8-7-544

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  • The thermogenic action of progesterone was shown in early studies in which progesterone was administered to men or to women with anovulatory cycles or amenorrhea, or in the follicular phase or luteal phase, or post-menopause.

    “The thermogenic action of progesterone was shown in early studies in which progesterone was administered to men [98] (Figure 3) or to women with anovulatory cycles or amenorrhea, or in the follicular phase or luteal phase, or post-menopause [62,63,99].”

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References 5 · Cited by 100

Authors
BUXTON, C. L., & ATKINSON, W. B.
Affiliations
Columbia University (US)
Venue
The Journal of Clinical Endocrinology & Metabolism
Published
1948-07
Volume
8
Issue
7
Pages
544-549
ISSN
  • 0021-972X (ISSN-L)
  • 1945-7197
OpenAlex
W2080491315
Cited by
100
References
5
Citations by year
2026: 1 · 2025: 1 · 2024: 2 · 2023: 6 · 2022: 4 · 2021: 5 · 2020: 4 · 2019: 4 · 2018: 3 · 2017: 2 · 2016: 1 · 2015: 4 · 2014: 2 · 2013: 1
FWCI
14.96
Type
journal article
Language
en
Open access
closed
Locations
  • The Journal of Clinical Endocrinology & Metabolism (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Reproductive Medicine › Hypothalamic control of reproductive hormones
  • Health Sciences › Medicine › Reproductive Medicine › Ovarian function and disorders
  • Life Sciences › Agricultural and Biological Sciences › Agronomy and Crop Science › Reproductive Physiology in Livestock
Keywords
basal body temperature, menstrual cycle, pregnancy, ovulation, luteal phase, hormonal regulation, pregnancy diagnosis
MeSH terms
Body Temperature, Female, Hormones, Menstrual Cycle, Pregnancy, Temperature, Basal Bodies

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