The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.
Cross-talk among ROR alpha 1 and the Rev-erb family of orphan nuclear receptors
Open accessAbstract
We have cloned Rev-erb beta, a novel isoform of the Rev-erb alpha orphan nuclear receptor. The DNA binding domains of Rev-erb alpha and beta are highly related to each other and to the retinoic acid related orphan receptor (ROR)/RZR subfamily of nuclear receptors. Indeed, we find that all three receptors bind as monomers to the sequence AATGT-AGGTCA. Whereas ROR alpha 1 constitutively activates transcription through this sequence, both isoforms of Rev-erb are inactive. When coexpressed, both Rev-erb isoforms suppress the transcriptional activity of ROR alpha 1. Our data define Rev-erb and ROR/RZR as a family of related receptors with opposing activities on overlapping regulatory networks.
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Activation of a member of the steroid hormone receptor superfamily by peroxisome proliferators
Issemann, I., & Green, S. (1990) · Nature · doi:10.1038/347645a0 · Cited by 3,519
A human retinoic acid receptor which belongs to the family of nuclear receptors
Petkovich, M., Brand, N. J., Krust, A., & Chambon, P. (1987) · Nature · doi:10.1038/330444a0 · Cited by 2,214
Identification of a receptor for the morphogen retinoic acid
Giguere, V., Ong, E. S., Segui, P., & Evans, R. M. (1987) · Nature · doi:10.1038/330624a0 · Cited by 1,965
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Cited by
Preitner, N., Damiola, F., Luis-Lopez-Molina, Zakany, J., Duboule, D., Albrecht, U., & Schibler, U. (2002) · Cell · doi:10.1016/s0092-8674(02)00825-5 · Cited by 2,198
Schoonjans, K., Staels, B., & Auwerx, J. (1996) · Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism · doi:10.1016/0005-2760(96)00066-5 · Cited by 1,047
Nuclear Receptor Expression Links the Circadian Clock to Metabolism
Yang, X., Downes, M., Yu, R. T., Bookout, A. L., He, W., Straume, M., Mangelsdorf, D. J., & Evans, R. M. (2006) · Cell · doi:10.1016/j.cell.2006.06.050 · Cited by 934
Differential Control of Bmal1 Circadian Transcription by REV-ERB and ROR Nuclear Receptors
Guillaumond, F., Dardente, H., Giguère, V., & Cermakian, N. (2005) · Journal of Biological Rhythms · doi:10.1177/0748730405277232 · Cited by 760
Nuclear receptors — a perspective from Drosophila
King-Jones, K., & Thummel, C. S. (2005) · Nature Reviews Genetics · doi:10.1038/nrg1581 · Cited by 586
Metadata
- Authors
- Forman, B. M.
- Venue
- Molecular Endocrinology
- Publisher
- The Endocrine Society
- Published
- 1994-09-01
- Volume
- 8
- Issue
- 9
- Pages
- 1253-1261
- ISSN
- 0888-8809 (ISSN-L)
- OpenAlex
- W2076311480
- Cited by
- 199
- References
- 3
- FWCI
- 3.49
- Type
- journal article
- Language
- en
- Open access
- bronze
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- Forman, B. M. (1994). Cross-talk among ROR alpha 1 and the Rev-erb family of orphan nuclear receptors. Molecular Endocrinology. https://doi.org/10.1210/me.8.9.1253
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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