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Nanosuspensions: a promising drug delivery strategy
Abstract
Nanosuspensions have emerged as a promising strategy for the efficient delivery of hydrophobic drugs because of their versatile features and unique advantages. Techniques such as media milling and high-pressure homogenization have been used commercially for producing nanosuspensions. Recently, the engineering of nanosuspensions employing emulsions and microemulsions as templates has been addressed in the literature. The unique features of nanosuspensions have enabled their use in various dosage forms, including specialized delivery systems such as mucoadhesive hydrogels. Rapid strides have been made in the delivery of nanosuspensions by parenteral, peroral, ocular and pulmonary routes. Currently, efforts are being directed to extending their applications in site-specific drug delivery.
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Cites
Nanoparticulate systems for brain delivery of drugs.
Kreuter, J. (2001) · Advanced Drug Delivery Reviews · doi:10.1016/s0169-409x(00)00122-8 · Cited by 1,107
Dissolution Testing as a Prognostic Tool for Oral Drug Absorption: Immediate Release Dosage Forms
Dressman, J. B., Amidon, G. L., Reppas, C., & Shah, V. P. (1998) · Pharmaceutical Research · doi:10.1023/a:1011984216775 · Cited by 1,097
Cited by
Thorat, A. A., & Dalvi, S. V. (2012) · Chemical Engineering Journal · doi:10.1016/j.cej.2011.12.044 · Cited by 438
Ali, H. S. M., York, P., Ali, A. M. A., & Blagden, N. (2011) · Journal of Controlled Release · doi:10.1016/j.jconrel.2010.10.007 · Cited by 253
Towards principled design of cancer nanomedicine to accelerate clinical translation
Souri, M., Soltani, M., Moradi Kashkooli, F., Kiani Shahvandi, M., Chiani, M., Shariati, F. S., Mehrabi, M. R., & Munn, L. L. (2022) · Materials Today Bio · doi:10.1016/j.mtbio.2022.100208 · Cited by 159
Metadata
- Authors
- Patravale, V. B., Date, A. A., & Kulkarni, R. M.
- Venue
- Journal of Pharmacy and Pharmacology
- Publisher
- Oxford University Press (OUP)
- Published
- 2004-07-01
- Volume
- 56
- Issue
- 7
- Pages
- 827-840
- ISSN
- 0022-3573 (ISSN-L)
- 2042-7158
- OpenAlex
- W2059225643
- Cited by
- 904
- References
- 2
- FWCI
- 5.22
- Type
- journal article
- Language
- en
- Open access
- closed
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- Patravale, V. B., Date, A. A., & Kulkarni, R. M. (2004). Nanosuspensions: a promising drug delivery strategy. Journal of Pharmacy and Pharmacology. https://doi.org/10.1211/0022357023691
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
