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Cited by 428

The DOI matches its Crossref record; 22 of the 22 references it cites were found in a registry or an index.

Timing of TIAs preceding stroke: Time window for prevention is very short

Rothwell, Peter M., Warlow, Charles P.·2005·Neurology

Abstract

BACKGROUND: Patients with TIA are at increased risk of ischemic stroke and require preventive treatment. However, clinical guidelines differ on how urgently patients should be assessed. OBJECTIVE: To determine the potential consequences of delays in investigation and treatment, the authors studied the timing of TIAs preceding ischemic stroke. METHODS: The authors studied patients who presented with a recent ischemic stroke and had a preceding TIA in two population-based studies (Oxford Vascular Study [OXVASC]; Oxfordshire Community Stroke Project [OCSP]) and two randomized trials (UK TIA Aspirin Trial [UK-TIA]; European Carotid Surgery Trial [ECST]). RESULTS: Of 2,416 patients who had presented with an ischemic stroke, 549 (23%) gave a history of a preceding TIA (18% in OXVASC, 15% in OCSP, 23% in UK-TIA, 26% in ECST). Where a preceding TIA had occurred, the timing was highly consistent across the studies, with 17% occurring on the day of the stroke, 9% on the previous day, and 43% at some point during the 7 days prior to the stroke. No clinical characteristics or vascular risk factors identified patients in whom there was a close temporal association between TIA and stroke. CONCLUSION: In patients presenting with ischemic stroke, TIAs occur most often during the hours and days immediately preceding the stroke.

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Metadata

Authors
Rothwell, P. M., & Warlow, C. P.
Venue
Neurology
Published
2005-03-08
Volume
64
Issue
5
Pages
817-820
ISSN
  • 0028-3878 (ISSN-L)
  • 1526-632X
OpenAlex
W2137539662
Cited by
428
References
22
FWCI
20.50
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Timing of TIAs preceding stroke: Time window for prevention is very short. https://app.cochat.ai/papers/10.1212/01.wnl.0000152985.32732.ee
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Rothwell, P. M., & Warlow, C. P. (2005). Timing of TIAs preceding stroke: Time window for prevention is very short. Neurology. https://doi.org/10.1212/01.wnl.0000152985.32732.ee

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