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Balshem, H., Helfand, M., Schünemann, H. J., Oxman, A. D., Kunz, R., Brozek, J., Vist, G. E., Falck-Ytter, Y., Meerpohl, J., & Norris, S. (2011) · Journal of Clinical Epidemiology · doi:10.1016/j.jclinepi.2010.07.015 · Cited by 8,285

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Guyatt, G. H., Oxman, A. D., Vist, G., Kunz, R., Brozek, J., Alonso-Coello, P., Montori, V., Akl, E. A., Djulbegovic, B., & Falck-Ytter, Y. (2011) · Journal of Clinical Epidemiology · doi:10.1016/j.jclinepi.2010.07.017 · Cited by 2,798

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Guyatt, G. H., Oxman, A. D., Kunz, R., Brozek, J., Alonso-Coello, P., Rind, D., Devereaux, P. J., Montori, V. M., Freyschuss, B., Vist, G., et al. (2011) · Journal of Clinical Epidemiology · doi:10.1016/j.jclinepi.2011.01.012 · Cited by 2,693

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Guyatt, G. H., Oxman, A. D., Kunz, R., Woodcock, J., Brozek, J., Helfand, M., Alonso-Coello, P., Glasziou, P., Jaeschke, R., Akl, E. A., et al. (2011) · Journal of Clinical Epidemiology · doi:10.1016/j.jclinepi.2011.03.017 · Cited by 2,320

Guidelines for the diagnosis and management of syncope (version 2009): The Task Force for the Diagnosis and Management of Syncope of the European Society of Cardiology (ESC)

Developed in collaboration with, European Heart Rhythm Association (EHRA), Heart Failure Association (HFA), and Heart Rhythm Society (HRS), societies, E. B. T. F., European Society of Emergency Medicine (EuSEM), European Federation of Internal Medicine (EFIM), European Union Geriatric Medicine Society (EUGMS), American Geriatrics Society (AGS), European Neurological Society (ENS), et al. (2009) · European Heart Journal · doi:10.1093/eurheartj/ehp298 · Cited by 2,040

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Guyatt, G. H., Oxman, A. D., Kunz, R., Woodcock, J., Brozek, J., Helfand, M., Alonso-Coello, P., Falck-Ytter, Y., Jaeschke, R., Vist, G., et al. (2011) · Journal of Clinical Epidemiology · doi:10.1016/j.jclinepi.2011.04.014 · Cited by 1,843

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Guyatt, G. H., Oxman, A. D., Montori, V., Vist, G., Kunz, R., Brozek, J., Alonso-Coello, P., Djulbegovic, B., Atkins, D., Falck-Ytter, Y., et al. (2011) · Journal of Clinical Epidemiology · doi:10.1016/j.jclinepi.2011.01.011 · Cited by 1,819

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Guyatt, G. H., Thorlund, K., Oxman, A. D., Walter, S. D., Patrick, D., Furukawa, T. A., Johnston, B. C., Karanicolas, P., Akl, E. A., Vist, G., et al. (2013) · Journal of Clinical Epidemiology · doi:10.1016/j.jclinepi.2012.08.001 · Cited by 772

Efficacy of Midodrine vs Placebo in Neurogenic Orthostatic Hypotension: A Randomized, Double-blind Multicenter Study

Low, P. A. (1997) · JAMA · doi:10.1001/jama.1997.03540370036033 · Cited by 425

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Jankovic, J., Gilden, J. L., Hiner, B. C., Kaufmann, H., Brown, D. C., Coghlan, C. H., Rubin, M., & Fouad-Tarazi, F. M. (1993) · The American Journal of Medicine · doi:10.1016/0002-9343(93)90230-m · Cited by 396

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Brignole, M., Moya, A., de Lange, F. J., Deharo, J.-C., Elliott, P. M., Fanciulli, A., Fedorowski, A., Furlan, R., Kenny, R. A., Martín, A., et al. (2018) · European Heart Journal · doi:10.1093/eurheartj/ehy037 · Cited by 1,951

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Palma, J., Gómez‐Esteban, J. C., Norcliffe‐Kaufmann, L., Martínez, J. A. B., Tijero, B., Berganzo, K., & Kaufmann, H. (2015) · Movement Disorders · doi:10.1002/mds.26079 · Cited by 186

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Prescott, H. C., Antonelli, M. M., Alhazzani, W. A., Møller, M. H., Alshamsi, F. E., Azevedo, L. C. P., Belley‐Côté, E. P., Waele, J. D., Derde, L. P. G., Dionne, J. C., et al. (2026) · Intensive Care Medicine · doi:10.1007/s00134-026-08361-1 · Cited by 149

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Prescott, H. C., Antonelli, M., Alhazzani, W., Møller, M. H., Alshamsi, F., Azevedo, L. C. P., Belley-Cote, E., De Waele, J., Derde, L., Dionne, J. C., et al. (2026) · Critical Care Medicine · doi:10.1097/ccm.0000000000007075 · Cited by 117

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Dani, M., Dirksen, A., Taraborrelli, P., Panagopolous, D., Torocastro, M., Sutton, R., & Lim, P. B. (2021) · Clinical Medicine · doi:10.7861/clinmed.2020-1044 · Cited by 111

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Joseph, A., Wanono, R., Flamant, M., & Vidal‐Petiot, E. (2017) · Néphrologie & Thérapeutique · doi:10.1016/j.nephro.2017.01.003 · Cited by 109

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Gul, A., Miskulin, D. C., Harford, A., & Zager, P. G. (2016) · Current Opinion in Nephrology & Hypertension · doi:10.1097/mnh.0000000000000271 · Cited by 70

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Wiblin, L., Lee, M. W., & Burn, D. J. (2016) · Parkinsonism & Related Disorders · doi:10.1016/j.parkreldis.2016.10.013 · Cited by 66

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Jones, P. K., Shaw, B. H., & Raj, S. R. (2015) · Expert Review of Cardiovascular Therapy · doi:10.1586/14779072.2015.1095090 · Cited by 62

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Chisholm, P., & Anpalahan, M. (2016) · Internal Medicine Journal · doi:10.1111/imj.13171 · Cited by 55

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Elgebaly, A. S., Abdelazeim, B., Mattar, O. M., Gadelkarim, M., Salah, R., & Negida, A. (2016) · Clinical Autonomic Research · doi:10.1007/s10286-016-0349-7 · Cited by 51

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Hale, G. M., Valdes, J., & Brenner, M. J. (2017) · Annals of Pharmacotherapy · doi:10.1177/1060028016689264 · Cited by 50

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Byun, J., Moon, J., Kim, D.-Y., Shin, H., Sunwoo, J., Lim, J., Kim, T., Lee, W. J., Lee, H. S., Jun, J., et al. (2017) · Neurology · doi:10.1212/wnl.0000000000004340 · Cited by 49

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Rizvi, M. S., Trivedi, V., Nasim, F., Lin, E., Kashyap, R., Andrijasevic, N. M., & Gajic, O. (2018) · Critical Care Medicine · doi:10.1097/ccm.0000000000003121 · Cited by 49

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Jans, Ø., Mehlsen, J., Kjærsgaard‐Andersen, P., Husted, H., Solgaard, S., Josiassen, J., Lunn, T. H., & Kehlet, H. (2015) · Anesthesiology · doi:10.1097/aln.0000000000000890 · Cited by 46

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Zhou, Y., Ke, S., Qiu, X., & Liu, L. (2017) · Medicine · doi:10.1097/md.0000000000008004 · Cited by 43

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Sheldon, R. S., Lei, L. Y., Guzmán, J. C., Kuś, T., Paredes, F. A., Angihan, J., Safdar, S., Maxey, C., Bennett, G., & Raj, S. R. (2019) · EP Europace · doi:10.1093/europace/euz250 · Cited by 35

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Khemani, P., & MEHDIRAD, A. A. (2019) · Cardiology in Review · doi:10.1097/crd.0000000000000280 · Cited by 34

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Jost, W. H. (2017) · International review of neurobiology · doi:10.1016/bs.irn.2017.04.003 · Cited by 32

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Katsi, V. K., Papakonstantinou, I. P., Solomou, E. G., Antonopoulos, A. S., Vlachopoulos, C. V., & Tsioufis, K. P. (2021) · Current Hypertension Reports · doi:10.1007/s11906-021-01146-5 · Cited by 32

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Frith, J., & Parry, S. W. (2016) · Age and Ageing · doi:10.1093/ageing/afw211 · Cited by 28

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Dani, M., Taraborrelli, P., Panagopoulos, D., Dirksen, A., Torocastro, M., Sutton, R., & Lim, P. B. (2022) · Age and Ageing · doi:10.1093/ageing/afac150 · Cited by 25

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Cheshire, W. P. (2017) · CONTINUUM Lifelong Learning in Neurology · doi:10.1212/con.0000000000000444 · Cited by 25

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Tanzer, T. D., Brouard, T., Pra, S. E. D., Warren, N., Barras, M. A., Kisely, S. R., Brooks, E., & Siskind, D. J. (2022) · Therapeutic Advances in Psychopharmacology · doi:10.1177/20451253221092931 · Cited by 24

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Dobrydnev, A. V., Tkachuk, T. M., Атаманюк, В. П., & Popova, M. V. (2019) · Mini-Reviews in Medicinal Chemistry · doi:10.2174/1389557519666191009152007 · Cited by 23

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Raj, S. R., & Sheldon, R. S. (2016) · Arrhythmia & Electrophysiology Review · doi:10.15420/aer.2016.7.2 · Cited by 24

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von Scheidt, W., Bosch, R., Klingenheben, T., Schuchert, A., Stellbrink, C., & Stockburger, M. (2019) · Der Kardiologe · doi:10.1007/s12181-019-0319-0 · Cited by 21

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Ballantyne, B. A., Letourneau-Shesaf, S., & Raj, S. R. (2021) · Autonomic Neuroscience · doi:10.1016/j.autneu.2021.102904 · Cited by 21

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Nair, S., Shah, J. V., Shah, P. A., Sanyal, M., & Shrivastav, P. S. (2015) · Cogent Chemistry · doi:10.1080/23312009.2015.1075852 · Cited by 20

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Lal, A., Trivedi, V., Rizvi, M. S., Amsbaugh, A., Myers, M. K., Saleh, K. M. M., Kashyap, R., & Gajic, O. (2021) · Critical Care Explorations · doi:10.1097/cce.0000000000000382 · Cited by 19

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Wong, L. Y., Wong, A., Robertson, T. A., Burns, K., Roberts, M. S., & Isbister, G. K. (2016) · Journal of Medical Toxicology · doi:10.1007/s13181-016-0574-4 · Cited by 19

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Saladini, F., Marco, A. D., & Palatini, P. (2016) · High Blood Pressure & Cardiovascular Prevention · doi:10.1007/s40292-016-0162-3 · Cited by 18

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Kuritzky, L., Espay, A. J., Gelblum, J., Payne, R., & Dietrich, E. A. (2015) · Postgraduate Medicine · doi:10.1080/00325481.2015.1050340 · Cited by 17

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Sinn, D.-I., & Gibbons, C. H. (2016) · Current Treatment Options in Neurology · doi:10.1007/s11940-016-0410-9 · Cited by 17

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Ziegler, D. (2016) · Wiley eBooks · doi:10.1002/9781118924853.ch40 · Cited by 16

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Vidal‐Petiot, E., Pathak, A., Azulay, J.-P., Traon, A. P., & Hanon, O. (2023) · Revue Neurologique · doi:10.1016/j.neurol.2023.11.001 · Cited by 15

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Jiang, Q., Zhang, L., Lin, J., Wei, Q., Li, C., Hou, Y., Ou, R., Liu, K., Yang, T., Xiao, Y., et al. (2023) · Journal of Parkinson s Disease · doi:10.3233/jpd-230095 · Cited by 14

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Traon, A. P., Foubert‐Samier, A., Ory‐Magne, F., Fabbri, M., Sénard, J., Meissner, W. G., Rascol, O., & Amar, J. (2021) · European Journal of Neurology · doi:10.1111/ene.15232 · Cited by 14

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Cutsforth‐Gregory, J. K. (2020) · CONTINUUM Lifelong Learning in Neurology · doi:10.1212/con.0000000000000818 · Cited by 14

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Rocha, E. A., Mehta, N., Távora‐Mehta, M. Z. P., Roncari, C. F., Cidrão, A. A. D. L., & Elías, J. (2021) · Arquivos Brasileiros de Cardiologia · doi:10.36660/abc.20200422 · Cited by 13

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Romano, S. L., Branz, L., Fondrieschi, L., & Minuz, P. (2019) · High Blood Pressure & Cardiovascular Prevention · doi:10.1007/s40292-019-00327-3 · Cited by 13

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Cerise, A. C., Chen, J. M., Powelson, J. A., Lutz, A. J., & Fridell, J. A. (2021) · Clinical Transplantation · doi:10.1111/ctr.14270 · Cited by 13

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Jensen, C. E., Byku, M., Hladik, G. A., Jain, K., Traub, R., & Tuchman, S. A. (2022) · Frontiers in Oncology · doi:10.3389/fonc.2022.907584 · Cited by 12

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Hebson, C. L., McConnell, M. E., & Hannon, D. W. (2018) · Congenital Heart Disease · doi:10.1111/chd.12720 · Cited by 12

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Kilcommons, S. J., Hammal, F., Kamaleldin, M., Opgenorth, D. L., Fiest, K. M., Karvellas, C. J., Kutsogiannis, D. J., Lau, V. I., MacIntyre, E. J., Rochwerg, B. N., et al. (2024) · Critical Care Medicine · doi:10.1097/ccm.0000000000006519 · Cited by 11

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Biswas, D., Karabin, B. L., & Turner, D. (2019) · International Journal of General Medicine · doi:10.2147/ijgm.s170655 · Cited by 11

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Hale, G. M., & Brenner, M. J. (2015) · Pharmacotherapy The Journal of Human Pharmacology and Drug Therapy · doi:10.1002/phar.1635 · Cited by 9

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Midodrine for severe orthostatic hypotension

(2016) · Drug and Therapeutics Bulletin · doi:10.1136/dtb.2016.5.0399 · Cited by 7

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Hwang, H., & Norris, S. A. (2021) · Journal of Geriatric Psychiatry and Neurology · doi:10.1177/08919887211018277 · Cited by 7

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Lakkireddy, D. (2019) · Journal of Atrial Fibrillation · doi:10.4022/jafib.2395 · Cited by 7

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Vecchié, A., THOMAS, G. K., Bressi, E., Bonaventura, A., Canada, J. M., Chuquin, D., Kadariya, D., Piracha, U. G., Endicott, D., Markley, R., et al. (2021) · Cardio-Oncology · doi:10.1186/s40959-021-00126-7 · Cited by 6

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Rocha, B. M. L., Gomes, R. V., Cunha, G., Silva, B. M. V., Pocinho, R. M., Morais, R., Araújo, I., & Fonseca, C. (2019) · Revista Portuguesa de Cardiologia · doi:10.1016/j.repc.2018.11.007 · Cited by 7

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Rocha, B. M. L., Gomes, R. V., Cunha, G., Silva, B. M. V., Pocinho, R. M., Morais, R., Araújo, I., & Fonseca, C. (2019) · Revista Portuguesa de Cardiologia (English Edition) · doi:10.1016/j.repce.2019.11.013 · Cited by 6

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Aminorroaya, A., Tavolinejad, H., Sadeghian, S., Jalali, A., Alaeddini, F., Emkanjoo, Z., Mollazadeh, R., Bozorgi, A., Oraii, S., Kiarsi, M., et al. (2021) · American Heart Journal · doi:10.1016/j.ahj.2021.03.002 · Cited by 6

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Ye, X., Ling, B., Wu, J., Wu, S.-J., Ren, Y., Zhang, H., Song, F., Xuan, Z., & Chen, M. (2020) · Medicine · doi:10.1097/md.0000000000021533 · Cited by 5

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Tavolinejad, H., Poopak, A., Sadeghian, S., Bozorgi, A., Oraii, A., Mollazadeh, R., Emkanjoo, Z., Kiarsi, M., Shahabi, J., Jalali, A., et al. (2022) · American Heart Journal · doi:10.1016/j.ahj.2022.04.002 · Cited by 5

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Lozano, T., & Ena, J. (2016) · Revista Clínica Española (English Edition) · doi:10.1016/j.rceng.2016.07.003 · Cited by 5

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Magny, E., Donadio, C., Maronnat, F., Nghiem, D., Berthelot, E., Belmin, J., & Lafuente‐Lafuente, C. (2019) · La Presse Médicale · doi:10.1016/j.lpm.2018.11.008 · Cited by 5

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Kulkarni, S., Jenkins, D., Dhar, A. S., & Mir, F. A. (2024) · Journal of Cardiovascular Pharmacology · doi:10.1097/fjc.0000000000001597 · Cited by 4

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Godbole, G., & Aggarwal, B. (2018) · Journal of Pharmacy Practice and Research · doi:10.1002/jppr.1484 · Cited by 4

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Sharma, V. K., & Vijayan, J. (2015) · Therapeutics and Clinical Risk Management · doi:10.2147/tcrm.s68439 · Cited by 4

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Lee, H. S., Song, J., Jung, M., Jo, Y., Kwon, J., & Cho, J. H. (2026) · European Heart Journal - Digital Health · doi:10.1093/ehjdh/ztag053 · Cited by 3

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