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Cerebral microembolism in symptomatic and asymptomatic high‐grade internal carotid artery stenosis

Siebler, M., Kleinschmidt, A., Sitzer, M., Steinmetz, H., Freund, H.-J.·1994·Neurology

Abstract

Using transcranial Doppler (TCD) ultrasonography in patients with high-grade (> or = 70%) internal carotid artery (ICA) stenosis, we examined the relation between the rate of TCD-detected silent microembolism of the ipsilateral middle cerebral artery and a history of recent (< 121 days) ischemic symptoms attributable to the diseased ICA. In the so-defined neurologically symptomatic group (n = 33 patients), silent microembolic events occurred in 27 subjects (overall mean rate, 14/h +/- 29). Among 56 neurologically asymptomatic patients matched for the degree of ICA stenosis, only nine showed such events (overall mean rate, 0.35/h +/- 1.4). Across all 89 patients studied, an individual microembolic event rate > or = 2/h had a positive predictive value of 0.88 for a history of recent symptoms. Our data suggest that TCD monitoring can provide reliable paraclinical evidence of "unstable ICA disease."

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Metadata

Authors
Siebler, M., Kleinschmidt, A., Sitzer, M., Steinmetz, H., & Freund, H.-J.
Venue
Neurology
Published
1994-04
Volume
44
Issue
4
Pages
615-615
ISSN
  • 0028-3878 (ISSN-L)
  • 1526-632X
OpenAlex
W1970057679
Cited by
194
References
0
FWCI
16.19
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Cerebral microembolism in symptomatic and asymptomatic high‐grade internal carotid artery stenosis. https://app.cochat.ai/papers/10.1212/wnl.44.4.615
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Siebler, M., Kleinschmidt, A., Sitzer, M., Steinmetz, H., & Freund, H.-J. (1994). Cerebral microembolism in symptomatic and asymptomatic high‐grade internal carotid artery stenosis. Neurology. https://doi.org/10.1212/wnl.44.4.615

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