The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
Abnormal cortical motor excitability in dystonia
Abstract
To assess the excitability of the motor system, we studied 11 patients with task-specific dystonia and 11 age-matched normal subjects. The dominant side was affected in nine of the patients. We delivered transcranial magnetic stimuli at different stimulus intensities and with different levels of muscle facilitation to the side contralateral to the side of electromyographic recording, and recorded motor evoked potentials (MEPs) from the flexor carpi radialis muscles bilaterally. The threshold intensity for eliciting MEPs at rest did not differ between patients and normal subjects. We compared the affected side in patients with the dominant side in normal subjects. With facilitation, the percentage of the area of the MEP to the M wave (MEP area%) was similar in both groups at low stimulus intensities, but with increasing stimulus intensity the increase in the MEP area% was greater in patients than in normal subjects (ANOVA, p < 0.001). The increase in MEP area% was similar in both groups with increasing facilitation levels. The duration of the silent period was similar in patients and normal subjects. We conclude that cortical motor excitability is increased in dystonia.
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Assessment [RETIRED]: Magnetoencephalography (MEG)
(1992) · Neurology · doi:10.1212/wnl.42.1.1 · Cited by 232
Measurement and prediction of functional capacity in Alzheimer's disease
Stern, Y., Hesdorffer, D., Sano, M., & Mayeux, R. (1990) · Neurology · doi:10.1212/wnl.40.1.8 · Cited by 147
Cited by
The pathophysiological basis of dystonias
Breakefield, X. O., Blood, A. J., Li, Y., Hallett, M., Hanson, P. I., & Standaert, D. G. (2008) · Nature Reviews Neuroscience · doi:10.1038/nrn2337 · Cited by 448
Self-citationAltered cortical excitability in obsessive–compulsive disorder
Greenberg, B. D., Ziemann, U., Corá-Locatelli, G., Harmon, A., Murphy, D. L., Keel, J. C., & Wassermann, E. M. (2000) · Neurology · doi:10.1212/wnl.54.1.142 · Cited by 285
Self-citationMechanisms influencing stimulus-response properties of the human corticospinal system
Boroojerdi, B., Battaglia, F., Muellbacher, W., & Cohen, L. G. (2001) · Clinical Neurophysiology · doi:10.1016/s1388-2457(01)00523-5 · Cited by 256
Gerdelat-Mas, A., Loubinoux, I., Tombari, D., Rascol, O., Chollet, F., & Simonetta-Moreau, M. (2005) · NeuroImage · doi:10.1016/j.neuroimage.2005.05.009 · Cited by 131
Metadata
- Authors
- Ikoma, K., Samii, A., Mercuri, B., Wassermann, E. M., & Hallett, M.
- Venue
- Neurology
- Published
- 1996-05
- Volume
- 46
- Issue
- 5
- Pages
- 1371-1371
- ISSN
- 0028-3878 (ISSN-L)
- 1526-632X
- OpenAlex
- W1968565302
- Cited by
- 239
- References
- 2
- FWCI
- 9.33
- Type
- journal article
- Language
- en
- Open access
- closed
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- Ikoma, K., Samii, A., Mercuri, B., Wassermann, E. M., & Hallett, M. (1996). Abnormal cortical motor excitability in dystonia. Neurology. https://doi.org/10.1212/wnl.46.5.1371
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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