The DOI matches its Crossref record; 26 of the 26 references it cites were found in a registry or an index.
Headache and major depression: Is the association specific to migraine?
Abstract
OBJECTIVE: To examine the relationship between migraine and major depression, by estimating the risk for first-onset major depression associated with prior migraine and the risk for first migraine associated with prior major depression. We also examined the extent to which comorbidity with major depression is specific to migraine or is observed in other severe headaches. METHODS: Representative samples of persons 25 to 55 years of age with migraine or other severe headaches (i.e., disabling headaches without migraine features) and controls with no history of severe headaches were identified by a telephone survey and later interviewed in person to ascertain history of common psychiatric disorders. RESULTS: Lifetime prevalence of major depression was approximately three times higher in persons with migraine and in persons with severe headaches compared with controls. Significant bidirectional relationships were observed between major depression and migraine, with migraine predicting first-onset depression and depression predicting first-onset migraine. In contrast, persons with severe headaches had a higher incidence of first-onset major depression (hazard ratio = 3.6), but major depression did not predict a significantly increased incidence of other severe headaches (hazard ratio = 1.6). CONCLUSIONS: The contrasting results regarding the relationship of major depression with migraine versus other severe headaches suggest that different causes may underlie the co-occurrence of major depression in persons with migraine compared with persons with other severe headaches.
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“In the general population, depression is associated with a wide range of health, mental health, and neurological conditions, such as 1) chronic pain [71–75]; 2) headaches and migraines [76–79]; 3) diabetes [80–82]; 4) low testosterone [83–85]; 5) cardiovascular, cerebrovascular, and small vessel ischemic disease [86–92]; 6) PD [93]; 7) MCI [94–96]; and 8) AD [97].”
From The Need to Separate Chronic Traumatic Encephalopathy Neuropathology from Clinical Features (2017) · cites this paper as [77]
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Cites
Regression Models and Life-Tables
Cox, D. R. (1972) · Journal of the Royal Statistical Society Series B: Statistical Methodology · doi:10.1111/j.2517-6161.1972.tb00899.x · Cited by 39,793
Sorge, F., Simone, R. D., Marano, E., Nolano, M., Orefice, G., & Carrieri, P. B. (1988) · Cephalalgia · doi:10.1046/j.1468-2982.1988.0801001.x · Cited by 3,464
Cox, D. R. (1975) · Biometrika · doi:10.1093/biomet/62.2.269 · Cited by 2,366
Wittchen, H.-U. (1994) · Journal of Psychiatric Research · doi:10.1016/0022-3956(94)90036-1 · Cited by 2,348
Covariance Analysis of Censored Survival Data
Breslow, N. E. (1974) · Biometrics · doi:10.2307/2529620 · Cited by 1,778
Prevalence of Migraine Headache in the United States
Stewart, W. F. (1992) · JAMA · doi:10.1001/jama.267.1.64 · Cited by 1,580
Self-citationChronic pain and depression: Does the evidence support a relationship?
Romano, J. M., & Turner, J. A. (1985) · Psychological Bulletin · doi:10.1037/0033-2909.97.1.18 · Cited by 732
Depression and somatization: a review
Katon, W. J., Kleinman, A., & Rosen, G. (1982) · The American Journal of Medicine · doi:10.1016/0002-9343(82)90816-6 · Cited by 530
Migraine, psychiatric disorders, and suicide attempts: An epidemiologic study of young adults
Breslau, N., Davis, G. C., & Andreski, P. M. (1991) · Psychiatry Research · doi:10.1016/0165-1781(91)90102-u · Cited by 515
Self-citationMerikangas, K. R. (1990) · Archives of General Psychiatry · doi:10.1001/archpsyc.1990.01810210057008 · Cited by 510
Research works printed but not linked: 3
- Fields H. Depression and pain: a neurobiological model. Neuropsychiatry, Neuropsychol, Behav Neurol 1991;4:83–92.
- Von Korff M, Simon G. The relationship between pain and depression. Br J Psychiatry 1996;30 (suppl):101–108.
- 10.1001/jama.1992.03480010072027 · DOI
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Premonitory symptoms in migraine
Giffin, N., Ruggiero, L., Lipton, R. B., Silberstein, S. D., Tvedskov, J. F., Olesen, J., Altman, J. S., Goadsby, P. J., & Macrae, A. (2003) · Neurology · doi:10.1212/01.wnl.0000052998.58526.a9 · Cited by 670
Self-citationHirschfeld, R. M. A. (2001) · The Primary Care Companion For CNS Disorders · doi:10.4088/pcc.v03n0609 · Cited by 661
Comorbidity of migraine and depression: Investigating potential etiology and prognosis
Breslau, N., Lipton, R. B., Stewart, W. F., Schultz, L. R., & Welch, K. M. A. (2003) · Neurology · doi:10.1212/01.wnl.0000058907.41080.54 · Cited by 640
Self-citationMillan, M. J. (2006) · Pharmacology & Therapeutics · doi:10.1016/j.pharmthera.2005.11.006 · Cited by 569
Migraine and its psychiatric comorbidities
Minen, M. T., de Dhaem, O. B., Diest, A. M. K. V., Powers, S. W., Schwedt, T. J., Lipton, R. B., & Silbersweig, D. (2016) · Journal of Neurology Neurosurgery & Psychiatry · doi:10.1136/jnnp-2015-312233 · Cited by 520
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Metadata
- Authors
- Breslau, N., Schultz, L. R., Stewart, W. F., Lipton, R. B., Lucia, V. C., & Welch, K. M. A.
- Affiliations
- University of Kansas (US)
- Venue
- Neurology
- Published
- 2000-01-25
- Volume
- 54
- Issue
- 2
- Pages
- 308-308
- ISSN
- 0028-3878 (ISSN-L)
- 1526-632X
- OpenAlex
- W1973174800
- Cited by
- 465
- References
- 26
- Citations by year
- 2026: 11 · 2025: 12 · 2024: 21 · 2023: 12 · 2022: 9 · 2021: 12 · 2020: 13 · 2019: 18 · 2018: 11 · 2017: 13 · 2016: 27 · 2015: 22 · 2014: 13 · 2013: 25 · 2012: 21
- FWCI
- 11.86
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Neurology (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Institutes of Health (5p50ns032399-05)
- National Institute of Neurological Disorders and Stroke (P50-NS32399)
- Topics
- Health Sciences › Medicine › Clinical Neurology › Migraine and Headache Studies
- Health Sciences › Medicine › Clinical Neurology › Traumatic Brain Injury Research
- Health Sciences › Dentistry › Oral Surgery › Temporomandibular Joint Disorders
- Keywords
- migraine, major depressive disorder, headache disorders, bidirectional relationship, comorbidities, first-episode depression, severe headache, depression risk, mental illness
- MeSH terms
- Adult, Depression, Female, Humans, Male, Michigan, Middle Aged, Risk Factors, Comorbidity, Incidence, Prevalence, Age of Onset, Migraine with Aura, Migraine without Aura
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