Amyotrophic lateral sclerosis in Olmsted County, Minnesota, 1925 to 1998
Abstract
The authors sought to determine trends in the incidence of ALS in Olmsted County from 1925 to 1998. Seventy-seven cases of ALS were identified during the period studied. The incidence rate remained stable at 1.7 cases per 100,000 people per year. Mean age at onset was 63 years. Mean survival was 23 months from diagnosis. Mean survival for patients or=60 years, it was 20 months (p = 0.02). Mean time from symptom onset to diagnosis was 13 months. Neither survival nor time to diagnosis changed significantly over time.
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The median survival time is well within the range reported by several population-based studies, which extends from 16 months to 28 months, with most studies reporting values between 19 and 23 months.
“it is well within the range reported by several population-based studies, which extends from 16 months (65;66) to 28 months (67), with most studies reporting values between 19 and 23 months (68–70).”
From Association of ALS with head injury, cigarette smoking and APOE genotypes (2010) · cites this paper as [68]
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Chiò, A., Logroscino, G., Traynor, B. J., Collins, J., Simeone, J. C., Goldstein, L. A., & White, L. A. (2013) · Neuroepidemiology · doi:10.1159/000351153 · Cited by 862 · see citing works
Association of ALS with head injury, cigarette smoking and APOE genotypes
Schmidt, S., Kwee, L. C., Allen, K. D., & Oddone, E. Z. (2010) · Journal of the Neurological Sciences · doi:10.1016/j.jns.2010.01.011 · Cited by 117 · see citing works
- Authors
- Sorenson, E. J., Stalker, A. P., Kurland, L. T., & Windebank, A. J.
- Affiliations
- From the Department of Neurology, Mayo Clinic, Rochester, MN.
- Venue
- Neurology
- Published
- 2002-07-23
- Volume
- 59
- Issue
- 2
- Pages
- 280-282
- ISSN
- 0028-3878
- 1526-632X
- Cited by
- 155
- References
- 0
- Language
- en
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