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Cited by 27Protist diversity and phylogenyMicrobial Metabolic Engineering and BioproductionAlgal biology and biofuel production

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Euglena International Network (EIN): Driving euglenoid biotechnology for the benefit of a challenged world

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Ebenezer, ThankGod Echezona, Low, Ross S., O'Neill, Ellis Charles, Huang, Ishuo, DeSimone, Antonio, Farrow, Scott C., Field, Robert A., Ginger, Michael L., Guerrero, Sergio Adrián, Hammond, Michael, Hampl, Vladimír, Horst, Geoff, Ishikawa, Takahiro, Karnkowska, Anna, Linton, Eric W., Myler, Peter, Nakazawa, Masami, Cardol, Pierre, Sánchez-Thomas, Rosina, Saville, Barry J., Shah, Mahfuzur R., Simpson, Alastair G. B., Sur, Aakash, Suzuki, Kengo, Tyler, Kevin M., Zimba, Paul V., Hall, Neil, Field, Mark C.·2022·Biology Open
DOI 10.1242/bio.059561PMC PMC9836076

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Abstract

Euglenoids (Euglenida) are unicellular flagellates possessing exceptionally wide geographical and ecological distribution. Euglenoids combine a biotechnological potential with a unique position in the eukaryotic tree of life. In large part these microbes owe this success to diverse genetics including secondary endosymbiosis and likely additional sources of genes. Multiple euglenoid species have translational applications and show great promise in production of biofuels, nutraceuticals, bioremediation, cancer treatments and more exotically as robotics design simulators. An absence of reference genomes currently limits these applications, including development of efficient tools for identification of critical factors in regulation, growth or optimization of metabolic pathways. The Euglena International Network (EIN) seeks to provide a forum to overcome these challenges. EIN has agreed specific goals, mobilized scientists, established a clear roadmap (Grand Challenges), connected academic and industry stakeholders and is currently formulating policy and partnership principles to propel these efforts in a coordinated and efficient manner.

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Metadata

Authors
Ebenezer, T. E., Low, R. S., O'Neill, E. C., Huang, I., DeSimone, A., Farrow, S. C., Field, R. A., Ginger, M. L., Guerrero, S. A., Hammond, M., Hampl, V., Horst, G., Ishikawa, T., Karnkowska, A., Linton, E. W., Myler, P., Nakazawa, M., Cardol, P., Sánchez-Thomas, R., Saville, B. J., Shah, M. R., Simpson, A. G. B., Sur, A., Suzuki, K., Tyler, K. M., Zimba, P. V., Hall, N., & Field, M. C.
Affiliations
  • European Bioinformatics Institute (GB)
  • Norwich Research Park (GB)
  • School of Chemistry, University of Nottingham 3 , Nottingham NG7 2RD , UK
  • Center for Food Safety and Applied Nutrition (US)
  • Scuola Superiore Sant'Anna (IT)
  • Trent University (CA)
  • University of Manchester (GB)
  • University of Huddersfield (GB)
  • Instituto de Agrobiotecnología del Litoral (AR)
  • Czech Academy of Sciences (CZ)
  • Charles University 12 , Faculty of Science, Department of Parasitology , , Vestec 25250 , Czech Republic
  • Kemin (Belgium) (BE)
  • Shimane University (JP)
  • University of Warsaw (PL)
  • Central Michigan University (US)
  • University of Washington (US)
  • Osaka Metropolitan University (JP)
  • University of Liège (BE)
  • Instituto Nacional de Cardiología, Ignacio Chávez 20 , Mexico 14080 , Mexico
  • Noblegen Inc. 6 Discovery Biology , , Peterborough, Ontario K9L 1Z8 , Canada
  • Dalhousie University (CA)
  • Euglena Co., Ltd. (Japan) (JP)
  • University of East Anglia (GB)
  • Virginia Commonwealth University (US)
  • University of Dundee (GB)
Corresponding author
  • Ebenezer, ThankGod Echezona
  • Ginger, Michael L.
  • Hall, Neil
  • Field, Mark C.
ORCID
Venue
Biology Open
Publisher
The Company of Biologists
Published
2022-11-01
Volume
11
Issue
11
ISSN
2046-6390 (ISSN-L)
DOI
10.1242/bio.059561
PMC
PMC9836076
OpenAlex
W4309664802
Cited by
27
References
4
Citations by year
2026: 7 · 2025: 5 · 2024: 8 · 2023: 4 · 2022: 3
FWCI
1.63
Type
journal article
Language
en
Open access
Licence
Locations
  • Biology Open (publishedVersion, cc-by)
  • PubMed Central (publishedVersion, cc-by)
  • PubMed (publishedVersion)
  • Discovery Research Portal (University of Dundee) (publishedVersion, cc-by)
  • Huddersfield Research Portal (University of Huddersfield) (publishedVersion, cc-by)
  • Research Explorer (The University of Manchester) (publishedVersion, other-oa)
  • Repository@Nottingham (University of Nottingham) (submittedVersion, cc-by)
  • UEA Digital Repository (University of East Anglia) (submittedVersion, other-oa)
  • ReIn UW (University of Warsaw) (submittedVersion, cc-by-nc-nd)
  • DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion)
  • Open Repository and Bibliography (University of Liège) (submittedVersion, cc-by)
  • OSF Preprints (OSF Preprints) (submittedVersion)
  • OSF Preprints (OSF Preprints) (submittedVersion, cc-by)
  • Greater South Information System
Funders
  • Biotechnology and Biological Sciences Research Council (BBS/E/J/000C0618, BBS/E/J/000PR9790, BBS/E/T/000PR9818)
  • Japan Society for the Promotion of Science (20H03119)
Topics
  • Life Sciences › Agricultural and Biological Sciences › Ecology, Evolution, Behavior and Systematics › Protist diversity and phylogeny
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Microbial Metabolic Engineering and Bioproduction
  • Physical Sciences › Energy › Renewable Energy, Sustainability and the Environment › Algal biology and biofuel production
Keywords
Euglena, Euglenophyta, secondary endosymbiosis, biofuels, nutraceuticals, bioremediation, cancer therapy, reference genome, metabolic pathway regulation, research collaboration networks, societal challenges
MeSH terms
Biotechnology, Euglena, Symbiosis

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