The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.
Hedgehog-GLI signaling regulates the behavior of cells with stem cell properties in the developing neocortex
Open accessAbstract
Stem cells are crucial for normal development and homeostasis, and their misbehavior may be related to the origin of cancer. Progress in these areas has been difficult because the mechanisms regulating stem cell lineages are not well understood. Here, we have investigated the role of the SHH-GLI pathway in the developing mouse neocortex. The results show that SHH signaling endogenously regulates the number of embryonic and postnatal mouse neocortical cells with stem cell properties, and controls precursor proliferation in a concentration-dependent manner in cooperation with EGF signaling. These findings identify a crucial mechanism for the regulation of the number of cells with stem cell properties that is unexpectedly conserved in different stem cell niches.
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Citations
Cites
Subventricular zone astrocytes are neural stem cells in the adult mammalian brain
Doetsch, F., Caillé, I., Lim, D. A., García-Verdugo, J. M., & Alvarez-Buylla, A. (1999) · Cell · doi:10.1016/s0092-8674(00)80783-7 · Cited by 3,898
Teratogen-Mediated Inhibition of Target Tissue Response to Shh Signaling
Cooper, M. K., Porter, J. A., Young, K. E., & Beachy, P. A. (1998) · Science · doi:10.1126/science.280.5369.1603 · Cited by 848
Hedgehog–GLI signaling and the growth of the brain
Ruiz i Altaba, A., Palma, V., & Dahmane, N. (2002) · Nature Reviews Neuroscience · doi:10.1038/nrn704 · Cited by 376
Self-citation
Cited by
Clement, V., Sanchez, P., de Tribolet, N., Radovanovic, I., & Ruiz i Altaba, A. (2007) · Current Biology · doi:10.1016/j.cub.2006.11.033 · Cited by 1,050
Neural stem cells: balancing self-renewal with differentiation
Doe, C. Q. (2008) · Development · doi:10.1242/dev.014977 · Cited by 420
Pietrobono, S., Gagliardi, S., & Stecca, B. (2019) · Frontiers in Genetics · doi:10.3389/fgene.2019.00556 · Cited by 303
Gli3 Is Required for Maintenance and Fate Specification of Cortical Progenitors
Wang, H., Ge, G., Uchida, Y., Luu, B., & Ahn, S. (2011) · The Journal of Neuroscience · doi:10.1523/jneurosci.4892-10.2011 · Cited by 93
Hasenpusch-Theil, K., West, S., Kelman, A., Kozic, Z., Horrocks, S., McMahon, A. P., Price, D. J., Mason, J. O., & Theil, T. (2018) · Development · doi:10.1242/dev.163147 · Cited by 54
Metadata
- Authors
- Palma, V., & Altaba, A. R. I.
- Venue
- Development
- Publisher
- The Company of Biologists
- Published
- 2004-01-15
- Volume
- 131
- Issue
- 2
- Pages
- 337-345
- ISSN
- 0950-1991 (ISSN-L)
- 1477-9129
- OpenAlex
- W1992375116
- Cited by
- 274
- References
- 3
- FWCI
- 5.68
- Type
- journal article
- Language
- en
- Open access
- green
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
