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Cited by 293

The DOI matches its Crossref record; 104 of the 104 references it cites were found in a registry or an index.

Mechanisms of thymus organogenesis and morphogenesis

Open access
Gordon, Julie, Manley, Nancy R.·2011·Development

Abstract

The thymus is the primary organ responsible for generating functional T cells in vertebrates. Although T cell differentiation within the thymus has been an area of intense investigation, the study of thymus organogenesis has made slower progress. The past decade, however, has seen a renewed interest in thymus organogenesis, with the aim of understanding how the thymus develops to form a microenvironment that supports T cell maturation and regeneration. This has prompted modern revisits to classical experiments and has driven additional genetic approaches in mice. These studies are making significant progress in identifying the molecular and cellular mechanisms that control specification, early organogenesis and morphogenesis of the thymus.

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Crossref · 10.1242/dev.059998

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Metadata

Authors
Gordon, J., & Manley, N. R.
Venue
Development
Published
2011-09-15
Volume
138
Issue
18
Pages
3865-3878
ISSN
  • 0950-1991 (ISSN-L)
  • 1477-9129
OpenAlex
W2143665979
Cited by
293
References
104
FWCI
6.87
Type
journal article
Language
en
Open access
green

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