The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.
Mice lacking the transcriptional corepressor TIF1β are defective in early postimplantation development
Abstract
TIF1β, a member of the transcriptional intermediary factor 1 family, has been reported to function as a corepressor for the large class of KRAB domain-containing zinc finger proteins of the Krüppel type. To address the biological function of TIF1β, we have generated TIF1β-deficient mice by gene disruption. TIF1β protein was detected in wild-type but not TIF1β−/− blastocysts. Homozygous mutant embryos, which developed normally until the blastocyst stage and underwent uterine implantation, were arrested in their development at the early egg-cylinder stage at about embryonic day (E) 5.5 and were completely resorbed by E8.5. Taken together, these results provide genetic evidence that TIF1β is a developmental regulatory protein that exerts function(s) essential for early postimplantation development.
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Cites
Structure and ligand of a histone acetyltransferase bromodomain
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DNA binding and transcriptional repression by DAX-1 blocks steroidogenesis
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Self-citation
Cited by
Ziv, Y., Bielopolski, D., Galanty, Y., Lukas, C., Taya, Y., Schultz, D. C., Lukas, J., Bekker-Jensen, S., Bartek, J., & Shiloh, Y. (2006) · Nature Cell Biology · doi:10.1038/ncb1446 · Cited by 735
TRIM/RBCC, a novel class of ‘single protein RING finger’ E3 ubiquitin ligases
Meroni, G., & Diez‐Roux, G. (2005) · BioEssays · doi:10.1002/bies.20304 · Cited by 730
Deconstructing repression: evolving models of co-repressor action
Perissi, V., Jepsen, K., Glass, C. K., & Rosenfeld, M. G. (2010) · Nature Reviews Genetics · doi:10.1038/nrg2736 · Cited by 532
Groner, A. C., Meylan, S., Ciuffi, A., Zangger, N., Ambrosini, G., Dénervaud, N., Bucher, P., & Trono, D. (2010) · PLoS Genetics · doi:10.1371/journal.pgen.1000869 · Cited by 364
KAP1 Protein: An Enigmatic Master Regulator of the Genome
Iyengar, S., & Farnham, P. J. (2011) · Journal of Biological Chemistry · doi:10.1074/jbc.r111.252569 · Cited by 367
Metadata
- Authors
- Cammas, F., Mark, M., Dollé, P., Dierich, A., Chambon, P., & Losson, R.
- Venue
- Development
- Publisher
- The Company of Biologists
- Published
- 2000-07-01
- Volume
- 127
- Issue
- 13
- Pages
- 2955-2963
- ISSN
- 0950-1991 (ISSN-L)
- 1477-9129
- OpenAlex
- W1900275723
- Cited by
- 212
- References
- 3
- FWCI
- 1.13
- Type
- journal article
- Language
- en
- Open access
- closed
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- Cammas, F., Mark, M., Dollé, P., Dierich, A., Chambon, P., & Losson, R. (2000). Mice lacking the transcriptional corepressor TIF1β are defective in early postimplantation development. Development. https://doi.org/10.1242/dev.127.13.2955
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