The DOI matches its Crossref record; 41 of the 41 references it cites were found in a registry or an index.
Abnormal lymphatic vessel development in neuropilin 2 mutant mice
Abstract
Neuropilin 2 is a receptor for class III semaphorins and for certain members of the vascular endothelial growth factor family. Targeted inactivation of the neuropilin 2 gene (Nrp2) has previously shown its role in neural development. We report that neuropilin 2 expression in the vascular system is restricted to veins and lymphatic vessels. Homozygous Nrp2 mutants show absence or severe reduction of small lymphatic vessels and capillaries during development. This correlated with a reduction of DNA synthesis in the lymphatic endothelial cells of the mutants. Arteries, veins and larger, collecting lymphatic vessels developed normally, suggesting that neuropilin 2 is selectively required for the formation of small lymphatic vessels and capillaries.
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Cites
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Self-citationProx1 Function Is Required for the Development of the Murine Lymphatic System
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Cited by
VEGF receptor signalling ? in control of vascular function
Olsson, A.-K., Dimberg, A., Kreuger, J., & Claesson-Welsh, L. (2006) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm1911 · Cited by 3,122
Phenotypic Heterogeneity of the Endothelium: II. Representative Vascular Beds
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Common mechanisms of nerve and blood vessel wiring
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Lymphatic vascular defects promoted by Prox1 haploinsufficiency cause adult-onset obesity
Harvey, N. L., Srinivasan, R. S., Dillard, M. E., Johnson, N. C., Witte, M. H., Boyd, K., Sleeman, M. W., & Oliver, G. (2005) · Nature Genetics · doi:10.1038/ng1642 · Cited by 580
Dynamics of endothelial cell behavior in sprouting angiogenesis
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Metadata
- Authors
- Yuan, L., Moyon, D., Pardanaud, L., Bréant, C., Karkkainen, M. J., Alitalo, K., & Eichmann, A.
- Venue
- Development
- Publisher
- The Company of Biologists
- Published
- 2002-10-15
- Volume
- 129
- Issue
- 20
- Pages
- 4797-4806
- ISSN
- 0950-1991 (ISSN-L)
- 1477-9129
- OpenAlex
- W2147153812
- Cited by
- 632
- References
- 41
- FWCI
- 12.20
- Type
- journal article
- Language
- en
- Open access
- closed
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- Yuan, L., Moyon, D., Pardanaud, L., Bréant, C., Karkkainen, M. J., Alitalo, K., & Eichmann, A. (2002). Abnormal lymphatic vessel development in neuropilin 2 mutant mice. Development. https://doi.org/10.1242/dev.129.20.4797
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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