Polyploidy in tissue homeostasis and regeneration

Øvrebø, Jan Inge, Edgar, Bruce A.·2018·Development

Cited by (147)

Items 101–147 of 147

  1. DNA synthesis increases during the first hours post-emergence in Anopheles albimanus mosquito midgut.
    Krystal Maya-Maldonado, Victor Cardoso-Jaime, S. Hernández-Martínez, Carlos Vázquez-Calzada, Fidel de la Cruz Hernández-Hernández, H. Lanz-Mendoza · 2020 · Developmental and Comparative Immunology
  2. Unscheduled polyploidy synergizes with oncogenic mutations to enhance genome instability and tumorigenesis
    Hunter C. Herriage, Cameron L. Hughes, Sarah K Fahey, Brian R. Calvi · 2025 · Cancer Letters
  3. Selective identification of polyploid hepatocellular carcinomas with poor prognosis by artificial intelligence-based pathological image recognition
    Takanori Matsuura, Masatoshi Abe, Yoshiyuki Harada, Masahiro Kido, Hajime Nagahara, Yuzo Kodama, Yoshihide Ueda, Eiji Hara, Hirohiko Niioka, Tomonori Matsumoto · 2025 · Communications Medicine
  4. An unscheduled switch to endocycles induces a reversible senescent arrest that impairs growth of the Drosophila wing disc
    Yiting Huang, Lauren L. Hesting, Brian R. Calvi · 2024 · PLoS Genetics
  5. Tissue Patterning: The Winner Takes It All, the Losers Standing Small.
    S. Dupont, Leonardo Morsut · 2019 · Current Biology
  6. Endomitosis: a new cell fate in the cell cycle leading to polyploidy in megakaryocytes and hepatocytes
    Q. Hua, Xue-Chun Zhang, Rui-Feng Tian, Zhi-Gang She, Zan Huang · 2025 · Journal of Zhejiang University SCIENCE B
  7. Premature endocycling of Drosophila follicle cells causes pleiotropic defects in oogenesis
    Hunter C. Herriage, B. Calvi · 2023 · bioRxiv
  8. Janus Face of Drug-Induced Tetraploidy in Non-Hodgkin Lymphoma.
    D. Mahadevan, Gregory C. Rogers · 2020 · Trends in Cancer
  9. Cell cycle variants during Drosophila accessory gland development
    A. Box, Navyashree A Ramesh, Shyama Nandakumar, S. J. Church, Dilan Prasad, Ariana Afrakhteh, R. Taichman, Laura A. Buttitta · 2019 · bioRxiv
  10. Emerging Strategies to Attack Polyploid Cancer Cells
    Jing Zhang, Shenqiu Zhang, Q. Shi, Dun Yang, Thaddeus David Allen · 2020
  11. Hepatocytes as Model for Investigating Natural Senotherapeutic Compounds and Their Effects on Cell Cycle Dynamics and Genome Stability
    A. Fizikova, A. Prokhorova, Daria Churikova, Zahar Konstantinov, Roman Ivanov, A. Karabelsky, S. Rybtsov · 2025 · International Journal of Molecular Sciences
  12. An Emerging Animal Model for Querying the Role of Whole Genome Duplication in Development, Evolution, and Disease
    Mara Schvarzstein, F. Alam, Muhammad Toure, J. Yanowitz · 2023 · Journal of Developmental Biology
  13. Endoreduplication in Drosophila melanogaster progeny after exposure to acute γ-irradiation
    D. Skorobagatko, A. Mazilov, V. Strashnyuk · 2018 · Radiation and Environmental Biophysics
  14. Hepatocyte Cell Cycle Progression Depends on a Transcriptional Repressor Cascade Downstream of Wnt Signaling
    Jin, Yinhua, Anbarchian, Teni, Wu, Peng, Sarkar, Abby, Fish, Matt, Nusse, Roel · 2021
  15. Intracellular buffering enables developmental robustness after genome doubling in C. elegans embryos.
    Miaoling Yang, Yu-Chuan Bai, Ziyi Wang, Zhuo Du · 2026 · Cell Reports
  16. Polyploidy-induced senescence: Linking development, differentiation, repair, and (possibly) cancer?
    Iman M. A. Al-Naggar, G. Kuchel · 2026 · Aging
  17. The Drosophila proventriculus lacks stem cells but compensates for age-related cell loss via endoreplication-mediated cell growth
    Ben Ewen-Campen, Weihang Chen, S. Tattikota, Ying Liu, Yan-Hui Hu, N. Perrimon · 2026 · bioRxiv
  18. Seasonal variation in endoreduplication and polyteny in the fruit fly Drosophila melanogaster (Diptera: Drosophilidae): How does it contribute to adaptation?
    V. Strashnyuk, E. Vakulenko, Yelyzaveta Koptevtsova · 2025 · European Journal of Entomology
  19. Aurora B inhibition promotes a hyper-polyploid state and continued endomitotic cycles in RB and p53 defective cells
    Shivam Vora, Ariel Andrew, Ramyashree Prasanna Kumar, Deborah Nazareth, Madushan Fernando, Mathew J. K. Jones, Yao-Wu He, John D. Hooper, Nigel A. J. McMillan, J. Urosevic et al. · 2024 · bioRxiv
  20. Significance of Multinucleated Polyploidization of Tubular Epithelial Cells in Kidney Allografts
    Noriyuki Kounoue, H. Oguchi, N. Tochigi, T. Mikami, Yutaka Yamaguchi, K. Honda, T. Yonekura, M. Muramatsu, Y. Itabashi, K. Sakai · 2023 · Nephron
  21. Dose‐related cardiac outcomes in response to postnatal dexamethasone treatment in premature lambs
    Amanda Vrselja, J. Pillow, J. Bensley, S. Ahmadi-Noorbakhsh, P. Noble, M. Black · 2023 · The Anatomical Record
  22. Conserved Chamber-Specific Polyploidy Maintains Heart Function in Drosophila
    Archan Chakraborty, Nora G Peterson, Juliet S. King, R. Gross, M. M. Pla, A. Thennavan, Kevin C. Zhou, Sophia DeLuca, N. Bursac, D. Bowles et al. · 2023 · bioRxiv
  23. Variability of polyteny of giant chromosomes in Drosophila melanogaster salivary glands
    V. Strashnyuk, L. Shakina, D. Skorobagatko · 2022 · Genetica
  24. Polyploidy in Lung Regeneration: Double Trouble or Dynamic Duo?
    Rachel L. Zemans · 2022 · American Journal of Respiratory Cell and Molecular Biology
  25. Insulin and the last gasp of failing adipocytes
    S. Rodriguez-Cuenca, A. Vidal-Puig · 2021 · Nature Metabolism
  26. The Role of Immunomodulator Betaleukin in Recovery of Hepatocytic Ploidy Profile in Delayed Terms after Irradiation
    L. P. Sycheva, L. M. Rozhdestvenskiĭ · 2020 · Bulletin of experimental biology and medicine
  27. Induction of endomitosis-like event in HeLa cells following CHK1 inhibitor treatment.
    Hisao Homma, H. Nojima, A. Kaida, M. Miura · 2019 · Biochemical and Biophysical Research Communications - BBRC
  28. Distinct p21 dynamics drive alternative routes to whole-genome duplication through a common CDK4/6-dependent polyploid G0 state
    Yian Yang, Anuraag Bukkuri, Dante Poe, Janet McLaughlin, Sihan Hao, Daniel D. Brown, Katarzyna M. Kedziora, Wayne Stallaert · 2026 · bioRxiv (Cold Spring Harbor Laboratory)
  29. Adaptive Potential of Intracolonial Genetic Variability in Coral Populations
    L. Afiq-Rosli, C. Duarte · 2025 · Ecology and Evolution
  30. StOSD1/UVI4 is crucial for accurate mitotic progression and the maintenance of leaf morphology in potato
    Mei-Ping Sun, Jiabao Lu, Lei Wu, Bo Wang, Jun Han, Yang Li, Hao Yang, Qi Xie, Zi-Tong Wang, Lu Yang et al. · 2025 · BMC Plant Biology
  31. A novel mechanism for centrosome expulsion ensures metabolic activity in polyploid cells
    Riham Salame, S. Gemble, A. Simon, L. Jawish, A. Macé, Ptissam Bergman, Graça Raposo, Clotilde Cadart, R. Basto · 2025 · bioRxiv
  32. Lineage-based scaling of germline intercellular bridges during oogenesis
    Umayr R. Shaikh, K. Sherlock, Julia Wilson, William D. Gilliland, Lindsay Lewellyn · 2024 · Development
  33. Lineage-based scaling of germline intercellular bridges during oogenesis
    Umayr R. Shaikh, K. Sherlock, Julia Wilson, William D. Gilliland, Lindsay Lewellyn · 2023 · bioRxiv
  34. The consequences of tetraploidy on Caenorhabditis elegans physiology and sensitivity to chemotherapeutics
    Kelly R. Misare, Elizabeth A. Ampolini, Hyland C. Gonzalez, Kaitlan A. Sullivan, Xin Li, C. Miller, Bintou Sosseh, Jaclyn B Dunne, C. Voelkel-Johnson, K. Gordon et al. · 2023 · bioRxiv
  35. Morphogenesis of a complex glial niche requires an interplay between cellular growth and fusion
    M. Rujano, D. Briand, Bojana Ðelić, P. Spéder · 2021 · bioRxiv
  36. Ablation of endogenously cycling adult cardiomyocytes worsens myocardial function after injury
    L. Bradley, Alexander P. Young, Helen O. Billcheck, Matthew J. Wolf · 2020 · bioRxiv
  37. In vitro and in vivo roles of glucocorticoid and vitamin D receptors in the control of cardiomyocyte proliferative potential
    S. Cutie, D. Lunn, Guo N. Huang · 2019 · bioRxiv
  38. [Hepatic polyploidy: Dr Jekyll or Mr Hyde].
    Romain Donné, Maëva Saroul, Vanessa Maillet, Séverine Celton-Morizur, C. Desdouets · 2019 · Medecine sciences : M/S
  39. The Sleeping Giant: Metabolism and Autophagy in the Generation and Survival of Dormant Polyploid Giant Cancer Cells
    Silvia Guil‐Luna, María Teresa Sánchez-Montero, Alejandra Díaz‐Chacón, Antonio Rodríguez‐Ariza · 2026 · MedComm
  40. Harnessing the endocycle for improved crop biomass and quality
    D. Sukma, Tsun-Ho Lam, M. Ohme-Takagi, M. Chan · 2026 · Plant Cell Tissue and Organ Culture
  41. Polyploid giant cancer cells: Survival, progeny formation, and therapeutic targeting
    Yuhe Ou, Lingwen Meng, Yuexuan Wang, Hong Xu, Xinyi Huang, Yixin Cao, Jing Zhang, Shujun Zeng · 2026 · Pathology - Research and Practice
  42. Plasticity of the endoreplication in insects: multifaceted roles in development and adaptation
    Si-Yi Wei, Lan-Xing Wang, Ming-Li Zhang, Peng Chen, Min-Hui Pan · 2026 · Journal of Resource Insects
  43. The immediate cellular response to whole-genome doubling is conserved across polyploid contexts
    Cindy C Geerlings, Gabriella S Darmasaputra, Christa Jordan Ortiz, Susana M. Chuva de Sousa Lopes, H. Clevers, M. Galli · 2026 · bioRxiv
  44. Spatial Variation in Cortex Glia Cell Cycle Supports Central Nervous System Organization in Drosophila
    Vaishali Yadav, Syona Tiwari, M. Meshram, Ramkrishna Mishra, Rakesh Pandey, R. Arya · 2026 · bioRxiv
  45. Consecutive endopolyploidy levels in cells of Branchipus schaefferi Fisher, 1834 (Branchiopoda: Anostraca)
    Alfredo Rosales-Ruiz, R. de la Herrán, F. Robles, R. Navajas-Pérez, José Carmelo Ruiz-Rejón · 2025 · Journal of Crustacean Biology
  46. α-catenin mechanosensitivity as a route to cytokinesis failure through sequestration of LZTS2
    Yu-Ou Wang, A. Yemelyanov, Christopher D. Go, Sun K. Kim, J. Quinn, Annette S. Flozak, Phuong M. Le, Shannon Liang, Anne Claude-Gingras, M. Ikura et al. · 2023 · bioRxiv
  47. Tetraploidy in rodent cardiac stem cells confers enhanced biological properties
    K. Broughton, T. Khieu, Nicky Nguyen, Michael Rosa, Sadia Mohsin, Pearl J. Quijada, Jessica Wang, O. Echeagaray, Dieter A. Kubli, Taeyong Kim et al. · 2019 · bioRxiv