Low peak bone mass and attenuated anabolic response to parathyroid hormone in mice with an osteoblast-specific deletion of connexin43

Chung, Dong Jin, Castro, Charlles H. M., Watkins, Marcus, Stains, Joseph P., Chung, Min Young, Szejnfeld, Vera Lucia, Willecke, Klaus, Theis, Martin +1 more·2006·Journal of Cell Science

Cited by (169)

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    Xin-Yue Zhang, Xiaohua Pu, Cai-Xia Pi, Jing Xie · 2023 · Life Science
  3. FGF7-induced E11 facilitates cell-cell communication through connexin43
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  4. PTH and PTHrP Actions on Kidney and Bone
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  5. Deficiency of the intermediate filament synemin reduces bone mass in vivo
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  6. Human Genetics of Sclerosing Bone Disorders
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  7. Connexin 43 Channels in Osteocytes Are Necessary for Bone Mass and Skeletal Muscle Function in Aged Male Mice
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  8. Up-regulation of BMP2/4 signaling increases both osteoblast-specific marker expression and bone marrow adipogenesis inGja1Jrt/+ stromal cell cultures
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  9. Connexin 43 Hemichannels Regulate Osteoblast to Osteocyte Differentiation
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  10. Nmp4/CIZ Suppresses the Response of Bone to Anabolic Parathyroid Hormone by Regulating Both Osteoblasts and Osteoclasts
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  11. Connexin 43 hemichannels and prostaglandin E2 release in anabolic function of the skeletal tissue to mechanical stimulation
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  12. FGF-7 Dictates Osteocyte Cell Processes Through Beta-Catenin Transduction
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  13. Risedronate increases osteoblastic differentiation and function through connexin43
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  14. Connexin43 modulates post-natal cortical bone modeling and mechano-responsiveness
    Susan K. Grimston, Marcus P. Watkins, Joseph P. Stains, Roberto Civitelli · 2013 · BoneKEy Reports
  15. Neuropeptide Y, substance P, and human bone morphogenetic protein 2 stimulate human osteoblast osteogenic activity by enhancing gap junction intercellular communication
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  16. Increasing Gap Junctional Coupling: A Tool for Dissecting the Role of Gap Junctions
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  17. A cost-effective method to enhance adenoviral transduction of primary murine osteoblasts and bone marrow stromal cells
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  18. Osteocytic connexin 43 is not required for the increase in bone mass induced by intermittent PTH administration in male mice.
    Rafael Pacheco‐Costa, Hannah M. Davis, Emily G. Atkinson, E. Katchburian, Lilian Irene Plotkin, Rejane Daniele Reginato · 2016 · PubMed Central
  19. Inhibition of osteoblastic differentiation by warfarin and 18-α-glycyrrhetinic acid
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  20. CONNEXIN 43 AND BONE: NOT JUST A GAP JUNCTION PROTEIN.
    Lilian Irene Plotkin · 2011 · Actualizaciones en osteología
  21. Transgenic mouse strains for conditional gene deletion during skeletal development
    Kyle K. VanKoevering, Bart O. Williams · 2008 · IBMS BoneKEy
  22. Determining how defects in connexin43 cause skeletal disease
    Quynh V. Ton, M. Kathryn Iovine · 2012 · genesis
  23. Connexin43 Modulation of Osteoblast/Osteocyte Apoptosis: A Potential Therapeutic Target?
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  24. Antagonistic Functions of Connexin 43 during the Development of Primary or Secondary Bone Tumors
    Julie Talbot, Maryne Dupuy, Sarah Morice, Françoise Rédiní, Franck Verrecchia · 2020 · Biomolecules
  25. Osterix plays a critical role in BMP4-induced promoter activity of connexin43
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  26. Inhibition of connexin 43 prevents trauma-induced heterotopic ossification
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  28. Regulation of gap junction function and Connexin 43 expression by cytochrome P450 oxidoreductase (CYPOR)
    Srikanth R. Polusani, Rekha Kar, Manuel A. Riquelme, Bettie Sue Siler Masters, Satya Prakash Panda · 2011 · Biochemical and Biophysical Research Communications
  29. Endothelin1-Induced Ca2+ Mobilization Is Altered in Calvarial Osteoblastic Cells of Cx43+/− Mice
    Graziello Geneau, Norah Defamie, Marc Mesnil, Laurent Cronier · 2007 · The Journal of Membrane Biology
  30. Effect of endothelin-1 on osteoblastic differentiation is modified by the level of connexin43: comparative study on calvarial osteoblastic cells isolated from Cx43+/−and Cx43+/+ mice
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  31. Connexin 43 and cell culture substrate differentially regulate OCY454 osteocytic differentiation and signaling to primary bone cells
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  32. Connexin43 in mesenchymal lineage cells regulates body adiposity and energy metabolism in mice
    Seung-Yon Lee, Francesca Fontana, Toshifumi Sugatani, Ignacio A. Portales Castillo, Giulia Leanza, Ariella L. G. Coler-Reilly, Roberto Civitelli · 2024 · JCI Insight
  33. Axial strain enhances osteotomy repair with a concomitant increase in connexin43 expression
    Rishi R Gupta, Hyunchul Kim, Yu-Kwan Chan, CARLA A. HEBERT, Ida Leah Gitajn, David J. Yoo, Robert V. O’Toole, Adam H. Hsieh, Joseph P. Stains · 2015 · Bone Research
  34. EPHs and ephrins: Many pathways to regulate osteoblasts and osteoclasts
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  35. Alcohol‐induced Wnt signaling inhibition during bone fracture healing is normalized by intermittent parathyroid hormone treatment
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  36. Gap Junctions and Biophysical Regulation of Bone Cells
    Shane A. J. Lloyd, Henry J. Donahue · 2010 · Clinical Reviews in Bone and Mineral Metabolism
  37. Role of Gap Junction, Hemichannels, and Connexin 43 in Mineralizing in Response to Intermittent and Continuous Application of Parathyroid Hormone
    Priscilla P. Cherian, Xuechun Xia, Jean Xin Jiang · 2008 · Cell Communication & Adhesion
  38. Effects of reduced connexin43 function on skull development in the Cx43I130T/+ mutant mouse that models oculodentodigital dysplasia
    Sommer G.E. Jarvis, Jae Eun Lee, Elizabeth Jewlal, Kevin Barr, Gregory Mitchell Kelly, Dale W. Laird, Katherine Elizabeth Willmore · 2020 · Bone
  39. Connexin hemichannels drive lactation-induced osteocyte acidification and perilacunar-canalicular remodeling
    Rui Hua, Vu A. Truong, Roberto J. Fajardo, Teja Guda, Sumin Gu, Jean Xin Jiang · 2024 · Cell Reports
  40. Intercellular Junctions and Cell–Cell Communication in the Skeletal System
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  41. Chinese Herbal Formula Huo-Luo-Xiao-Ling Dan Protects against Bone Damage in Adjuvant Arthritis by Modulating the Mediators of Bone Remodeling
    Siddaraju M. Nanjundaiah, David Y.W. Lee, Brian Berman, Kamal D. Moudgil · 2013 · Evidence-based Complementary and Alternative Medicine
  42. Connexin43 in Musculoskeletal System: New Targets for Development and Disease Progression
    Senbo An, Shengyuan Zheng, Zijun Cai, Siyu Chen, Chen Wang, Yusheng Li, Zhenhan Deng · 2022 · Aging and Disease
  43. Intercellular junctions and cell–cell communication in the skeletal system
    Joseph P. Stains, Francesca Fontana, Roberto Civitelli · 2019 · Elsevier eBooks
  44. Molecular Actions of Parathyroid Hormone
    Leila Revollo, Roberto Civitelli · 2014 · Elsevier eBooks
  45. Parathyroid hormone and parathyroid hormone–related protein actions on bone and kidney
    Alessandro Bisello, Peter A. Friedman · 2019 · Elsevier eBooks
  46. KLF5 promotes the ossification process of ligamentum flavum by transcriptionally activating CX43
    Hubing Guo, Lingxia Yang, Jin Liu, Liqi Chen, Yufeng Huang, Jinsong Li · 2024 · Journal of Orthopaedic Surgery and Research
  47. Connexin 43 contributes to phenotypic robustness of the mouse skull
    Elizabeth Jewlal, Kevin Barr, Dale W. Laird, Katherine Elizabeth Willmore · 2021 · Developmental Dynamics
  48. Osteocyte Biology
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    Krzysztof Łukowicz, Karolina Fijał, Aleksandra Nowak, Anna M. Osyczka · 2020 · Postępy Higieny i Medycyny Doświadczalnej
  50. Connexins in Skeletal Biology
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  52. Parathyroid Hormone and Parathyroid-Hormone-Related Protein: Normal Function, Diseases, and Emerging Therapeutics
    Ling Qin, Nicola C. Partridge · 2012 · Springer eBooks
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  57. Gap junction in bone remodeling and in primary bone tumors: osteosarcoma and Ewing sarcoma
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  58. Connexin-Mediated Signaling in Bone
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