Uses and abuses of macropinocytosis

Bloomfield, Gareth, Kay, Robert R.·2016·Journal of Cell Science

Cited by (193)

Items 101–193 of 193

  1. Discovery of a Macropinocytosis‐Inducing Peptide Potentiated by Medium‐Mediated Intramolecular Disulfide Formation
    Jan Vincent V. Arafiles, H. Hirose, Yusuke Hirai, Masashi Kuriyama, Maxwell Mamfe Sakyiamah, Wataru Nomura, Kazuhiro Sonomura, Miki Imanishi, Akira Otaka, Hirokazu Tamamura et al. · 2021 · Angewandte Chemie International Edition
  2. Applying Spatiotemporal Modeling of Cell Dynamics to Accelerate Drug Development
    Xindong Chen, Shihao Xu, Bizhu Chu, Jing Guo, Hui-Kai Zhang, Shu-Yi Sun, Le Song, Xi‐Qiao Feng · 2024 · ACS Nano
  3. Nanomedicines for Subcellular Targeting: The Mitochondrial Perspective
    Olakunle Oladimeji, Jude Akinyelu, Moganavelli Singh · 2019 · Current Medicinal Chemistry
  4. No Catalyst Added Hydrogen Peroxide Oxidation of Dextran: An Environmentally Friendly Route to Multifunctional Polymers
    Ekaterina V. Pronina, Yuri A. Vorotnikov, Tatiana N. Pozmogova, Anastasiya O. Solovieva, Svetlana M. Miroshnichenko, Pavel E. Plyusnin, Denis P. Pishchur, Ilia V. Eltsov, Mariya Edeleva, Michael A. Shestopalov et al. · 2020 · ACS Sustainable Chemistry & Engineering
  5. Unconjugated p-cresol activates macrophage macropinocytosis leading to increased LDL uptake
    Lee Daniel Chaves, Sham Abyad, Amanda M. Honan, Mark A. Bryniarski, Daniel Ian McSkimming, Corrine M. Stahura, Steven C. Wells, Donna M. Ruszaj, Marilyn E. Morris, Richard John Quigg et al. · 2021 · JCI Insight
  6. Lipid nanoparticles: A delicate nucleic acid delivery system to be further explored
    Runpu Ma, Yuting Li, Yang Su, Peng Chen, Sitao Xie, Weihong Tan, Xiangsheng Liu · 2024 · Nano Today
  7. Signaling Pathways that Regulate Macropinocytosis in Mammalian Cells
    Wilhelm Palm · 2022 · Sub-cellular biochemistry/Subcellular biochemistry
  8. Amplification of PIP3 signalling by macropinocytic cups
    Robert R. Kay, Thomas D. Williams, Peggy Paschke · 2018 · Biochemical Journal
  9. Living on soup: macropinocytic feeding in amoebae
    Robert R. Kay, Thomas D. Williams, James D. Manton, David Traynor, Peggy Paschke · 2019 · The International Journal of Developmental Biology
  10. Endocytosis-mediated redistribution of antibiotics targets intracellular bacteria
    Shaoqi Qu, Kui Zhu · 2023 · Nanoscale
  11. Key Process and Factors Controlling the Direct Translocation of Cell-Penetrating Peptide through Bio-Membrane
    Kazutami Sakamoto, Taku Morishita, Kenichi Aburai, Kenichi Sakai, Masahiko Abe, Ikuhiko Nakase, Shiroh Futaki, Hideki Sakai · 2020 · International Journal of Molecular Sciences
  12. Membrane dynamics in cell migration
    Montserrat Llanses, Elena Rainero · 2019 · Essays in Biochemistry
  13. Microbe-host interactions: structure and functions of Gram-negative bacterial membrane vesicles
    Min Xiao, Guiding Li, Hefeng Yang · 2023 · Frontiers in Microbiology
  14. Mechanical stretch regulates macropinocytosis in Hydra vulgaris
    Taylor D. Skokan, Bert Hobmayer, Kara L. McKinley, Ronald D. Vale · 2024 · Molecular Biology of the Cell
  15. Genomic insights into the cellular specialization of predation in raptorial protists
    Zaihan Li, Xiao Chen, Fangqing Zhao, Miao Miao · 2024 · BMC Biology
  16. Theranostic Nanoparticles and Their Spectrum in Cancer
    Anca Onaciu, Ancuta Maria Jurj, Cristian Silviu Moldovan, Ioana Berindan-Neagoe · 2019 · IntechOpen eBooks
  17. New methods to decrypt emerging macropinosome functions during the host–pathogen crosstalk
    Yuen‐Yan Chang, Jost Enninga, Virginie Stévenin · 2021 · Cellular Microbiology
  18. Image-based Quantification of Macropinocytosis Using Dextran Uptake into Cultured Cells
    Hoang Anh Le, Laura M. Machesky · 2022 · BIO-PROTOCOL
  19. Actin Waves and Dynamic Patterning of the Plasma Membrane.
    Guenther Gerisch, Jana Prassler, Nelson Butterfield, Mary Ecke · 2019 · Europe PMC (PubMed Central)
  20. Endocytic highways: Navigating macropinocytosis and other endocytic routes for precision drug delivery
    Rabin Neupane, Saloni Malla, Chandrabose Karthikeyan, Charles R. Asbhy, Sai H. S. Boddu, Ramapuram Jayachandra Babu, Amit Kumar Tiwari · 2025 · International Journal of Pharmaceutics
  21. The nanomorphology of cell surfaces of adhered osteoblasts
    Christian Völkner, Mirco Wendt, Regina Lange, Max Ulbrich, Martina Gruening, Susanne Staehlke, Barbara J. Nebe, Ingo Barke, S. Speller · 2021 · Beilstein Journal of Nanotechnology
  22. C2GAP2 is a common regulator of Ras signaling for chemotaxis, phagocytosis, and macropinocytosis
    Xuehua Xu, Henderikus Pots, Bernd K. Gilsbach, Dustin Parsons, Douwe M. Veltman, Sharmila G. Ramachandra, Haoran Li, Arjan Kortholt, Tian Jin · 2022 · Frontiers in Immunology
  23. KRASG12R-Independent Macropinocytosis in Pancreatic Cancer
    G. Aaron Hobbs, Channing J. Der · 2022 · Sub-cellular biochemistry/Subcellular biochemistry
  24. The F-actin-binding RapGEF GflB is required for efficient macropinocytosis in Dictyostelium
    Hironori Inaba, Koji Yoda, Hiroyuki Adachi · 2017 · Journal of Cell Science
  25. Identification and Validation of Amino Acid Metabolism-Related Biomarkers and Investigation of their Potential Mechanisms in Lung Adenocarcinoma
    Zhu Xu, Ying Zhang, Peiying Pan, Xinlei Liu, Jian Zhang, Xiaojun Du, Tao Wang, Yin Teng, Chao Fan, Jianglun Li et al. · 2025 · Current Gene Therapy
  26. Distinct forms of the actin cross-linking protein α-actinin support macropinosome internalization and trafficking
    Kevin M. Burton, Katherine M. Johnson, Eugene W. Krueger, Gina L. Razidlo, Mark A. McNiven · 2021 · Molecular Biology of the Cell
  27. Gold Nanoparticles Inhibit Macropinocytosis by Decreasing KRAS Activation
    Chandra Kumar Elechalawar, Geeta Rao, Suresh Kumar Gulla, Maulin Mukeshchandra Patel, Alex N. Frickenstein, Nicolas Means, Ram Vinod Roy, Leonidas Tsiokas, Sima Asfa, Prasanta Panja et al. · 2023 · ACS Nano
  28. Excitable Ras dynamics-based screens reveal RasGEFX is required for macropinocytosis and random cell migration
    Koji Iwamoto, Satomi Matsuoka, Masahiro Ueda · 2025 · Nature Communications
  29. A Novel Method to Image Macropinocytosis in Vivo
    Lunhao Chen, Daxiao Cheng, Jiachen Chu, Ting Zhang, Zhuoer Dong, Huifang Lou, Liya Zhu, Yijun Liu · 2018 · Frontiers in Neuroscience
  30. Effects of Acanthamoeba castellanii on the dissolved oxygen and the microbial community under the experimental aquatic model
    Chih-Ming Tsai, Jenn‐Wei Chen, Wei-Chen Lin · 2020 · Experimental Parasitology
  31. Macropinocytosis and Cell Migration: Don’t Drink and Drive…
    Maria–Graciela Delgado, Claudia A. Rivera, Ana‐Maria Lennon‐Duménil · 2022 · Sub-cellular biochemistry/Subcellular biochemistry
  32. Caveolae-dependent endocytosis mediates the cellular uptake of CdTe quantum dots in ovarian cancer cell lines
    Zahra Asadian, Hakimeh Zare, Mahmoud Aghaei, Mojtaba Panjehpour · 2022 · Research in Pharmaceutical Sciences
  33. Macropinocytosis as a potential mechanism driving neurotropism of Cryptococcus neoformans
    Dylan M Lanser, Amelia B. Bennett, Kiem Vu, Angie Gelli · 2023 · Frontiers in Cellular and Infection Microbiology
  34. Macrophage imaging and subset analysis using single-cell RNA sequencing
    Sean P. Arlauckas, Nuri Oh, Ran Li, Ralph Weissleder, Miles Aaron Miller · 2020 · Nanotheranostics
  35. Targeting Wnt-driven metabolic adaptations in cancer: integrating glycolysis, glutaminolysis, IDO1-mediated immune evasion, and therapeutic delivery strategies
    Eric Flores-Hernández, Grace Binder, Kuo‐Ching Mei, Nydia Tejeda‐Muñoz · 2025 · Frontiers in Cell and Developmental Biology
  36. Physicochemical characterization, biodistribution, and bio‐effects of fluorescent carbon dots from roasted Spanish mackerel
    Guoxin Cui, Jiaqi Li, Jiaxuan Li, Haitao Wang, Mingqian Tan · 2023 · Food Frontiers
  37. High-throughput Measurement of Dictyostelium discoideum Macropinocytosis by Flow Cytometry
    Thomas D. Williams, Robert R. Kay · 2018 · Journal of Visualized Experiments
  38. Does macrovesicular endocytosis occur in fungal hyphae?
    Igor S. Mazheika, Olga V. Kamzolkina · 2021 · Fungal Biology Reviews
  39. The Amoebal Model for Macropinocytosis
    Robert R. Kay, Judith E. Lutton, Helena L.E. Coker, Peggy Paschke, Jason King, Till Bretschneider · 2022 · Sub-cellular biochemistry/Subcellular biochemistry
  40. Investigating the Role of Translationally Control Tumor Protein in Growth, Development and Differentiation of Dictyostelium discoideum
    Rakesh Kumar, Ranjana Maurya, Shweta Saran · 2020 · Frontiers in Cell and Developmental Biology
  41. Cysteine Metabolism in Cancer Progression and Therapy Resistance
    Dawn Sijin Nin, Shabana Binte Idres, Lih‐Wen Deng · 2021 · Springer eBooks
  42. A Novel Role of Dickkopf-Related Protein 3 in Macropinocytosis in Human Bladder Cancer T24 Cells
    Nonoka Tsujimura, Nami O. Yamada, Yuki Kuranaga, Minami Kumazaki, Haruka Shinohara, Kohei Taniguchi, Yukihiro Akao · 2016 · International Journal of Molecular Sciences
  43. Quantifying Carcinoembryonic Antigen-like Cell Adhesion Molecule-Targeted Liposome Delivery Using Imaging Flow Cytometry
    Jason Kuhn, Asya Smirnov, Alison K. Criss, Linda M. Columbus · 2019 · Molecular Pharmaceutics
  44. Extracellular ATP and Macropinocytosis: Their Interactive and Mutually Supportive Roles in Cell Growth, Drug Resistance, and EMT in Cancer
    Maria Evers, Jingwen Song, Xiaozhuo Chen · 2022 · Sub-cellular biochemistry/Subcellular biochemistry
  45. Modulation of infectious Salmon Anaemia virus infection by clathrin-mediated endocytosis and macropinocytosis inhibitors
    Matías Cárdenas, Sofía Michelson, Claudia Galleguillos, Yesseny Vásquez‐Martínez, Marcelo Cortez‐San Martín · 2024 · Research in Veterinary Science
  46. B Lymphocyte as a Target of Bacterial Infections
    Jorge Ismael Castañeda‐Sánchez, Ana Rosa Muñóz-Duarte, María Lilia Domínguez‐López, Juan José De la Cruz-López, Julieta Luna‐Herrera · 2017 · InTech eBooks
  47. Intracellular Delivery: An Overview
    Dhanashree H. Surve, Prajakta P. Dandekar, Padma V. Devarajan, Anil B. Jindal · 2019 · AAPS advances in the pharmaceutical sciences series
  48. Macropinocytosis: the Achilles’ heel of pancreatic cancer?
    Carl Andreasson, Daniel Ansari, Fredrik Ekbom, Roland E. Andersson · 2020 · Scandinavian Journal of Gastroenterology
  49. A Transdermal Prion‐Bionics Supermolecule as a RAB3A Antagonist for Enhancing Facial Youthfulness
    Wenjia Liu, Fan Ding, Wenguang Yang, Weiming You, Liqiang Zhang, Wangxiao He · 2024 · Advanced Science
  50. Transduction enhancing EF-C peptide nanofibrils are endocytosed by macropinocytosis and subsequently degraded
    Lena Rauch‐Wirth, Desirée Schütz, Rüdiger M. Groß, Sascha Rode, Bernhard Glocker, Janis A. Müller, Paul Walther, Clarissa Read, Jan Münch · 2024 · Biomaterials
  51. Is cell migration a selectable trait in the natural evolution of cancer development?
    Andrea Disanza, Sara Bisi, Emanuela Frittoli, Chiara Malinverno, Stefano Marchesi, Andrea Palamidessi, Abrar Rizvi, Giorgio Scita · 2019 · Philosophical Transactions of the Royal Society B Biological Sciences
  52. ATP triggers macropinocytosis that internalizes and is regulated by PANX1
    Andrew K. J. Boyce, Emma van der Slagt, Juan C. Sanchez‐Arias, Leigh Anne Swayne · 2020 · bioRxiv (Cold Spring Harbor Laboratory)
  53. Subcellular Cartography of the Phosphoinositide Multiverse
    Morgan M.C. Ricci, Claire C. Weckerly, Gerald R. V. Hammond · 2025 · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids
  54. Nanoparticle-based vaccines and future vaccine technologies
    Srivatsa Surya Vasudevan, Tiba Yamin Kandrikar, Adil Ali Sayyed, Pallab Sarker, Neeha Sultana Nasir, Sruthi Venugopalan, Regash Mariajohn, Vivek P. Chavda, Piyush Gondaliya · 2024 · Elsevier eBooks
  55. Intracellular protozoan parasites: living probes of the host cell surface molecular repertoire
    Georgios Pavlou, Geneviève Milon, Isabelle Tardieux · 2019 · Current Opinion in Microbiology
  56. Endocytosis
    Georgeta N. Basturea · 2019 · Materials and Methods
  57. ATP2B4 is an essential gene for epidermal growth factor‐induced macropinocytosis in A431 cells
    Shunsuke Yoshie, Masashi Kuriyama, Masashi Maekawa, Wei Guo Xu, Takuro Niidome, Shiroh Futaki, H. Hirose · 2024 · Genes to Cells
  58. Discovery of a Macropinocytosis‐Inducing Peptide Potentiated by Medium‐Mediated Intramolecular Disulfide Formation
    Jan Vincent V. Arafiles, H. Hirose, Yusuke Hirai, Masashi Kuriyama, Maxwell Mamfe Sakyiamah, Wataru Nomura, Kazuhiro Sonomura, Miki Imanishi, Akira Otaka, Hirokazu Tamamura et al. · 2021 · Angewandte Chemie
  59. Cellular Inflammatory Responses
    Walter Gottlieb Land · 2018 · Springer eBooks
  60. Exploration of Deformation of F-Actin during Macropinocytosis by Confocal Microscopy and 3D-Structured Illumination Microscopy
    Linyu Xu, Yanwei Zhang, Song Lang, Yan Jun Gong · 2022 · Photonics
  61. Amphibian pore-forming protein βγ-CAT drives extracellular nutrient scavenging under cell nutrient deficiency
    Ling‐Zhen Liu, Long Liu, Zhihong Shi, Xian‐Ling Bian, Zi-Ru Si, Qiquan Wang, Yang Xiang, Yun Zhang · 2023 · iScience
  62. Endocytosis: RasGAPs Help Organize Macropinocytic Cups
    Robert R. Kay · 2020 · Current Biology
  63. Listeria monocytogenes Co-opts Caveolin-Mediated E-cadherin Trafficking and Macropinocytosis for Epithelial Cell-to-Cell Spread
    Prathima Radhakrishnan, Mugdha Sathe, Julie A. Theriot · 2022 · bioRxiv (Cold Spring Harbor Laboratory)
  64. Pore-forming protein βγ-CAT drives extracellular nutrient scavenging under cell starvation
    Ling‐Zhen Liu, Long Liu, Zhihong Shi, Xian‐Ling Bian, Qiquan Wang, Yang Xiang, Yun Zhang · 2022 · bioRxiv (Cold Spring Harbor Laboratory)
  65. ATP increases murine neuroblastoma cell size through a PANX1- and macropinocytosis-dependent mechanism
    Andrew K. J. Boyce, Emma van der Slagt, Leigh E. Wicki‐Stordeur, Leigh Anne Swayne · 2025 · Biology Open
  66. The Lysosome–Cathepsin Axis in Pancreatic Cancer: Mechanisms of Stromal Remodeling, Immune Evasion, and Therapy Resistance
    Nika Mazej Jeram, Emanuela Senjor, Janko Kos, Milica Perišić Nanut · 2026 · Biomolecules
  67. Hypersensitivity of Vps33B mutant flies to non‐pathogenic infections is dictated by aberrant activation of p38b MAP kinase
    Jiän Zhang, Charles Tracy, Chandrashekhar Pasare, Jinsheng Zeng, Helmut Krämer · 2020 · Traffic
  68. Synthesis of guanidinium‐dendrimer‐type pDNA carriers for gene delivery into floating blood cells
    Ryoto Kon, Shoichiro Asayama · 2023 · Polymers for Advanced Technologies
  69. High-throughput Measurement of Dictyostelium discoideum Macropinocytosis by Flow Cytometry
    THOMAS M. WILLIAMS, Robert R. Kay · 2018 · Journal of Visualized Experiments
  70. Co-ordinated Ras and Rac activity shapes macropinocytic cups and enables phagocytosis of geometrically diverse bacteria
    Catherine M. F. Buckley, Henderikus Pots, Aurélie Guého, Ben A. Phillips, Bernd K. Gilsbach, David Traynor, Anton Nikolaev, Thierry Soldati, Andrew J. Parnell, Arjan Kortholt et al. · 2019 · bioRxiv (Cold Spring Harbor Laboratory)
  71. Rab5 regulates macropinosome closure through recruitment of the inositol 5-phosphatases OCRL/Inpp5b and the hydrolysis of PtdIns(4,5)P 2
    Michelle E. Maxson, Helen Sarantis, Allen Volchuk, John Hunter Brumell, Sergio Grinstein · 2020 · bioRxiv (Cold Spring Harbor Laboratory)
  72. Piezo1 activation using Yoda1 inhibits macropinocytosis and proliferation of cancer cells
    Masashi Kuriyama, H. Hirose, Toshihiro Masuda, Masachika Shudou, Jan Vincent V. Arafiles, Miki Imanishi, Masashi Maekawa, Yuji Hara, Shiroh Futaki · 2021 · bioRxiv (Cold Spring Harbor Laboratory)
  73. Исследование иммуногенности и потенциальной протективности вакцины «ЭпиВакКорона»
    Андрей Криницкий · 2021
  74. Macropinocytosis of aggregated amyloid-beta and tau requires Arf6 and the RhoGTPases Rac1, Cdc42 and RhoA
    Jordan M Krupa, Manoj Reddy Medapati, Adrianna R Tsang, Claudia Seah, Stephen Pasternak · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
  75. Investigating the Role of EphrinB1 in the Control of Xenopus laevis Gastrulation
    Jason W. H. Wen · 2018 · TSpace (University of Toronto)
  76. Macrophage Surveillance and Immunity: Eating, Drinking, and Digesting
    Philip P. Ostrowski · 2020 · TSpace (University of Toronto)
  77. Visualizing Key Signaling Components of Macropinocytosis and Phagocytosis Using Confocal Microscopy in the Model Organism Dictyostelium discoideum
    Xuehua Xu, Joseph A. Brzostowski, Sharmila G. Ramachandra, Smit Bhimani, Yan You, Tian Jin · 2021 · Methods in molecular biology
  78. Extracellular vesicles in Shiga toxin-mediated disease
    Annie Willysson · 2021 · Lund University Publications (Lund University)
  79. Ny fart på Silly Season
    Johan Karlsson · 2007
  80. Vesicle-Mediated Transcytosis and Export of Viruses
    Efraín E. Rivera-Serrano, Stanley M. Lemon · 2020 · Elsevier eBooks
  81. Recovery of fibroblasts from membrane attack by S. aureus α-toxin does not depend on acid sphingomyelinase but involves macropinocytosis
    Gisela von Hoven, Claudia Neukirch, Carolin Neukirch, Martina Meyenburg, Sandra Ritz, Matthias Husmann · 2023 · bioRxiv (Cold Spring Harbor Laboratory)
  82. The Role of KRAS in Macropinocytosis and its Implications of Multi-Drug Resistance in Cancer
    Ferenc Fenyvesi, Zeinab Ibrahim · 2024 · De Remediis
  83. Novel macropinocytosis inducers selectively modulate intracellular delivery of small and macromolecules in cancer cells
    Rabin Neupane, Chandrabose Karthikeyan, Veronica Piedra, Mariah A. Pasternak, Sai H. S. Boddu, Charles R. Ashby, Ramapuram Jayachandra Babu, Amit Kumar Tiwari · 2025 · International Journal of Biological Macromolecules
  84. An integrated framework for evolution of ciliated protists (Protista, Ciliophora) from the perspective of comparative genomics
    Yuexin Wang, Didi Jin, Xiaopeng Hou, Khaled A. S. Al‐Rasheid, Chen Shao, T. Zhang · 2025 · Molecular Phylogenetics and Evolution
  85. Additional file 1 of Genomic insights into the cellular specialization of predation in raptorial protists
    Zaihan Li, Chen, Xiao, Zhao, Fangqing, Miao Miao · 2024 · Figshare
  86. Macropinocytosis Generates New Microridge Patterns in Fish Epidermis Cells
    Joseph A. DePasquale · 2026 · Acta Zoologica
  87. Infection of human placental cells by Brucella
    Karellen Beren García Méndez · 2017
  88. Toxoplasma gondii, a super fast runner and cell invader. Studying motion and forces
    Georgios Pavlou · 2020
  89. Les amibes comme approche thérapeutique pour lutter contre les bactéries multirésistantes aux antibiotiques
    Félix Bornier · 2022 · theses.fr (ABES)
  90. The gp120 Envelope Glycoprotein of HIV-1 Triggers Macropinocytosis in Primary CD4+ T Cells to Promote HIV-1 Infection
    Praveen Manivannan, Cristina Santos da Costa, Yipei Tang, Xinghao Wang, Joel A. Swanson, Tomoyuki Murakami, Akira Ono, Philip D. King · 2026 · bioRxiv (Cold Spring Harbor Laboratory)
  91. Liposomal nanocarriers in retinoblastoma: from molecular design to clinical translation
    Tahura Fayeghi Arjmand, Ahmad Shojaei, MirAhmad Mazloomi, Effat Alizadeh · 2026 · Cancer Nanotechnology
  92. Time-Varying Low-Frequency Electromagnetic Fields and Endothelial Angiogenesis: From Early In Vitro Discoveries to Emerging Mechanisms
    Linghong Li, Wayne F. Patton · 2026 · Pathophysiology
  93. GCLC Deficiency Enhances Cellular Uptake of BNCT Agents via Oxidative Stress-Induced Macropinocytosis
    Qing Zhang, Yujiao Wang, Junhui Zhang, Zhenwei Liang, Linwen Lv, Chuan Du, Quegula Bamutijiang, Jiayi Wang, Dingkang Ren, Xian Gong et al. · 2026 · Nano Letters