Cooperative and independent roles of the Drp1 adaptors Mff, MiD49 and MiD51 in mitochondrial fission

NIH Image to ImageJ: 25 years of image analysis

Schneider, C. A., Rasband, W. S., & Eliceiri, K. W. (2012) · Nature Methods · doi:10.1038/nmeth.2089 · Cited by 64,638

Andromeda: A Peptide Search Engine Integrated into the MaxQuant Environment

Cox, J., Neuhauser, N., Michalski, A., Scheltema, R. A., Olsen, J. V., & Mann, M. (2011) · Journal of Proteome Research · doi:10.1021/pr101065j · Cited by 5,520

The BCL-2 protein family: opposing activities that mediate cell death

Youle, R. J., & Strasser, A. (2007) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm2308 · Cited by 4,806

Protocol for micro-purification, enrichment, pre-fractionation and storage of peptides for proteomics using StageTips

Rappsilber, J., Mann, M., & Ishihama, Y. (2007) · Nature Protocols · doi:10.1038/nprot.2007.261 · Cited by 4,641

Double nicking by RNA-guided CRISPR Cas9 for enhanced genome editing specificity

Ran, F. A., Hsu, P. D., Lin, C.-Y., Gootenberg, J. S., Konermann, S., Trevino, A. E., Scott, D. A., Inoue, A., Matoba, S., Zhang, Y., et al. (2013) · Cell · doi:10.1016/j.cell.2013.08.021 · Cited by 3,299

The ubiquitin kinase PINK1 recruits autophagy receptors to induce mitophagy

Lazarou, M., Sliter, D. A., Kane, L. A., Sarraf, S. A., Wang, C., Burman, J. L., Sideris, D. P., Fogel, A. I., & Youle, R. J. (2015) · Nature · doi:10.1038/nature14893 · Cited by 2,774

ER Tubules Mark Sites of Mitochondrial Division

Friedman, J. R., Lackner, L. L., West, M., DiBenedetto, J. R., Nunnari, J., & Voeltz, G. K. (2011) · Science · doi:10.1126/science.1207385 · Cited by 2,072

Mitochondrial dynamics-fusion, fission, movement, and mitophagy-in neurodegenerative diseases

Chen, H., & Chan, D. C. (2009) · Human Molecular Genetics · doi:10.1093/hmg/ddp326 · Cited by 1,506

Mitochondria in Apoptosis: Bcl-2 Family Members and Mitochondrial Dynamics

Martinou, J., & Youle, R. J. (2011) · Developmental Cell · doi:10.1016/j.devcel.2011.06.017 · Cited by 1,395

CHOPCHOP: a CRISPR/Cas9 and TALEN web tool for genome editing

Montague, T. G., Cruz, J. M. B. S., Gagnon, J. A., Church, G. M., & Valen, E. (2014) · Nucleic Acids Research · doi:10.1093/nar/gku410 · Cited by 1,246

Mitochondrial plasticity and synaptic plasticity crosstalk; in health and Alzheimer's disease

Sayehmiri, F., Motamedi, F., Batool, Z., Naderi, N., Shaerzadeh, F., Zoghi, A., Rezaei, O., Khodagholi, F., & Pourbadie, H. G. (2024) · CNS Neuroscience & Therapeutics · doi:10.1111/cns.14897 · Cited by 68

The Protein Coded by a Short Open Reading Frame, Not by the Annotated Coding Sequence, Is the Main Gene Product of the Dual-Coding Gene MIEF1

Delcourt, V., Brunelle, M., Roy, A. V., Jacques, J., Salzet, M., Fournier, I., & Roucou, X. (2018) · Molecular & Cellular Proteomics · doi:10.1074/mcp.ra118.000593 · Cited by 70

Drp1/Mff signaling pathway is involved in fluoride-induced abnormal fission of hepatocyte mitochondria in mice

Zhou, B.-H., Wei, S.-S., Jia, L.-S., Zhang, Y., Miao, C.-Y., & Wang, H. (2020) · The Science of The Total Environment · doi:10.1016/j.scitotenv.2020.138192 · Cited by 62

Mechanobiology of organelles: illuminating their roles in mechanosensing and mechanotransduction

Phuyal, S., Romani, P., Dupont, S., & Farhan, H. (2023) · Trends in Cell Biology · doi:10.1016/j.tcb.2023.05.001 · Cited by 63

The Role of Mitochondrial Dynamics and Mitotic Fission in Regulating the Cell Cycle in Cancer and Pulmonary Arterial Hypertension: Implications for Dynamin-Related Protein 1 and Mitofusin2 in Hyperproliferative Diseases

Colpman, P., Dasgupta, A., & Archer, S. L. (2023) · Cells · doi:10.3390/cells12141897 · Cited by 66

High‐throughput screening identifies suppressors of mitochondrial fragmentation in OPA1 fibroblasts

Cretin, E., Lopes, P. T., Vimont, E., Tatsuta, T., Langer, T., Gazi, A. D., Sachse, M., Yu‐Wai‐Man, P., Reynier, P., & Wai, T. (2021) · EMBO Molecular Medicine · doi:10.15252/emmm.202013579 · Cited by 63

Mitochondrial dynamics regulators: implications for therapeutic intervention in cancer

Kumar, S., Ashraf, R., & Aparna, C. K. (2021) · Cell Biology and Toxicology · doi:10.1007/s10565-021-09662-5 · Cited by 61

The Multifaceted Regulation of Mitochondrial Dynamics During Mitosis

Pangou, E., & Sumara, I. (2021) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2021.767221 · Cited by 66

Apoptotic foci at mitochondria: in and around Bax pores

Ugarte‐Uribe, B., & García‐Sáez, A. J. (2017) · Philosophical Transactions of the Royal Society B Biological Sciences · doi:10.1098/rstb.2016.0217 · Cited by 59

Reinventing an Organelle: The Reduced Mitochondrion in Parasitic Protists

Santos, H. J., Makiuchi, T., & Nozaki, T. (2018) · Trends in Parasitology · doi:10.1016/j.pt.2018.08.008 · Cited by 61

Mortal engines: Mitochondrial bioenergetics and dysfunction in neurodegenerative diseases

Joshi, A. U., & Mochly‐Rosen, D. (2018) · Pharmacological Research · doi:10.1016/j.phrs.2018.08.010 · Cited by 57

Mitochondria in brain diseases: Bridging structural-mechanistic insights into precision-targeted therapies

Liao, J., He, W., Li, L., Wang, J., Gong, L., Zhang, Q., & Lin, Z. (2025) · Cell Biomaterials · doi:10.1016/j.celbio.2025.100016 · Cited by 63

Diabetic Pregnancy and Maternal High-Fat Diet Impair Mitochondrial Dynamism in the Developing Fetal Rat Heart by Sex-Specific Mechanisms

Larsen, T. D., Sabey, K. H., Knutson, A. J., Gandy, T. C. T., Louwagie, E. J., Lauterboeck, L., Mdaki, K. S., & Baack, M. L. (2019) · International Journal of Molecular Sciences · doi:10.3390/ijms20123090 · Cited by 57

Increased mitochondrial fission of glomerular podocytes in diabetic nephropathy

Ma, Y., Chen, Z., Tao, Y., Zhu, J., Yang, H., Liang, W., & Ding, G. (2019) · Endocrine Connections · doi:10.1530/ec-19-0234 · Cited by 55

Mitophagy as a Protective Mechanism against Myocardial Stress

Nah, J., Miyamoto, S., & Sadoshima, J. (2017) · Comprehensive physiology · doi:10.1002/cphy.c170005 · Cited by 60

Endothelial FIS1 DeSUMOylation Protects Against Hypoxic Pulmonary Hypertension

Zhou, X., Jiang, Y., Wang, Y., Fan, L., Zhu, Y., Chen, Y., Wang, Y., Zhu, Y., Wang, H., Pan, Z., et al. (2023) · Circulation Research · doi:10.1161/circresaha.122.321200 · Cited by 57

Novel insights into the role of mitochondrial fusion and fission in cardiomyocyte apoptosis induced by ischemia/reperfusion

Li, Y., & Liu, X. (2018) · Journal of Cellular Physiology · doi:10.1002/jcp.26522 · Cited by 56

Aberrant Drp1-mediated mitochondrial division presents in humans with variable outcomes

Whitley, B. N., Lam, C. T., Cui, H., Haude, K. M., Bai, R., Escobar, L., Hamilton, A., Brady, L., Tarnopolsky, M. A., Dengle, L., et al. (2018) · Human Molecular Genetics · doi:10.1093/hmg/ddy287 · Cited by 53

Noncanonical PDK4 action alters mitochondrial dynamics to affect the cellular respiratory status

Thoudam, T., Chanda, D., Sinam, I. S., Kim, B., Kim, M.-J., Oh, C. J., Lee, J. Y., Kim, M., Park, S. Y., Lee, S. Y., et al. (2022) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2120157119 · Cited by 53

Mitochondrial fission factor is a novel Myc-dependent regulator of mitochondrial permeability in cancer

Seo, J. H., Agarwal, E., Chae, Y. C., Lee, Y. G., Garlick, D. S., Storaci, A. M., Ferrero, S., Gaudioso, G., Gianelli, U., Vaira, V., et al. (2019) · EBioMedicine · doi:10.1016/j.ebiom.2019.09.017 · Cited by 49

Multifaceted functions of Drp1 in hypoxia/ischemia-induced mitochondrial quality imbalance: from regulatory mechanism to targeted therapeutic strategy

Hao, S., Huang, H., Ma, R., Zeng, X., & Duan, C. (2023) · Military Medical Research · doi:10.1186/s40779-023-00482-8 · Cited by 59

Parkin-independent mitophagy via Drp1-mediated outer membrane severing and inner membrane ubiquitination

Oshima, Y., Cartier, E. A., Boyman, L., Verhoeven, N. A., Polster, B. M., Huang, W., Kane, M. A., Lederer, W. J., & Karbowski, M. (2021) · The Journal of Cell Biology · doi:10.1083/jcb.202006043 · Cited by 51

The Role of Mitochondrial Quality Control in Cognitive Dysfunction in Diabetes

Luo, J.-S., Ning, J., Chen, Z.-Y., Li, W., Zhou, R., Yan, R., Chen, M., & Ding, L.-L. (2022) · Neurochemical Research · doi:10.1007/s11064-022-03631-y · Cited by 52

The structural biology of the dynamin‐related proteins: New insights into a diverse, multitalented family

Ford, M. G. J., & Chappie, J. S. (2019) · Traffic · doi:10.1111/tra.12676 · Cited by 48

Mitochondrial Dynamics: Molecular Mechanisms, Related Primary Mitochondrial Disorders and Therapeutic Approaches

Nottia, M. D., Verrigni, D., Torraco, A., Rizza, T., Bertini, E., & Carrozzo, R. (2021) · Genes · doi:10.3390/genes12020247 · Cited by 51

Balancing life and death: BCL‐2 family members at diverse ER–mitochondrial contact sites

Means, R. E., & Katz, S. G. (2021) · FEBS Journal · doi:10.1111/febs.16241 · Cited by 50

Functional role of PGAM5 multimeric assemblies and their polymerization into filaments

Ruiz, K., Thaker, T. M., Agnew, C., Miller-Vedam, L. E., Trenker, R., Herrera, C., Ingaramo, M., Toso, D. B., Frost, A. S., & Jura, N. (2019) · Nature Communications · doi:10.1038/s41467-019-08393-w · Cited by 47

The relevance of mitochondrial morphology for human disease

Navaratnarajah, T., Anand, R., Reichert, A. S., & Distelmaier, F. (2021) · The International Journal of Biochemistry & Cell Biology · doi:10.1016/j.biocel.2021.105951 · Cited by 49

Is mitochondrial morphology important for cellular physiology?

Wai, T. (2024) · Trends in Endocrinology and Metabolism · doi:10.1016/j.tem.2024.05.005 · Cited by 50

Astragaloside IV combined with ligustrazine ameliorates abnormal mitochondrial dynamics via Drp1 SUMO / deSUMOylation in cerebral ischemia–reperfusion injury

Chen, X., Yang, T., Zhou, Y., Mei, Z., & Zhang, W. (2024) · CNS Neuroscience & Therapeutics · doi:10.1111/cns.14725 · Cited by 46

Regulation of mitochondrial bioenergetics by the non-canonical roles of mitochondrial dynamics proteins in the heart

Wang, W., Fernández‐Sanz, C., & Sheu, S. (2017) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/j.bbadis.2017.09.004 · Cited by 46

Insight into the fission mechanism by quantitative characterization of Drp1 protein distribution in the living cell

Michalska, B., Kwapiszewska, K., Szczepanowska, J., Kalwarczyk, T., Patalas‐Krawczyk, P., Szczepański, K., Hołyst, R., Duszyński, J., & Szymański, J. (2018) · Scientific Reports · doi:10.1038/s41598-018-26578-z · Cited by 46

Role of mitochondrial fission-related genes in mitochondrial morphology and energy metabolism in mouse embryonic stem cells

Seo, B. J., Choi, J., La, H., Habib, O., Choi, Y., Hong, K., & Tae, J. (2020) · Redox Biology · doi:10.1016/j.redox.2020.101599 · Cited by 44

Mediators of mitophagy that regulate mitochondrial quality control play crucial role in diverse pathophysiology

De, R., Mazumder, S., & Bandyopadhyay, U. (2020) · Cell Biology and Toxicology · doi:10.1007/s10565-020-09561-1 · Cited by 47

Swimming Exercise Alleviates Endothelial Mitochondrial Fragmentation via Inhibiting Dynamin-Related Protein-1 to Improve Vascular Function in Hypertension

Li, G., Xu, K., Xing, W., Yang, H., Li, Y., Wang, X., Zhou, J., An, J., Dong, L., Zhang, X., et al. (2022) · Hypertension · doi:10.1161/hypertensionaha.122.19126 · Cited by 44

Mitochondrial Function and Reactive Oxygen/Nitrogen Species in Skeletal Muscle

Chen, M., Li, Y., Deng, S., Zhao, Y., Lian, Z., & Yu, K. (2022) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2022.826981 · Cited by 49

Human Fis1 directly interacts with Drp1 in an evolutionarily conserved manner to promote mitochondrial fission

Nolden, K. A., Harwig, M. C., & Hill, R. B. (2023) · Journal of Biological Chemistry · doi:10.1016/j.jbc.2023.105380 · Cited by 42

The role of mitochondrial dynamics in disease

Wang, Y., Dai, X., Li, H., Jiang, H., Zhou, J.-F., Zhang, S., Guo, J., Shen, L., Yang, H., Lin, J. M., et al. (2023) · MedComm · doi:10.1002/mco2.462 · Cited by 41

Molecular Biomarkers of the Mitochondrial Quality Control Are Differently Affected by Hypoxia-Reoxygenation Stress in Marine Bivalves Crassostrea gigas and Mytilus edulis

Steffen, J. B. M., Falfushynska, H., Piontkivska, H., & Sokolova, I. M. (2020) · Frontiers in Marine Science · doi:10.3389/fmars.2020.604411 · Cited by 46

Adrenergic Regulation of Drp1-Driven Mitochondrial Fission in Cardiac Physio-Pathology

Jhun, B. S., O‐Uchi, J., Adaniya, S. M., Cypress, M. W., & Yoon, Y. (2018) · Antioxidants · doi:10.3390/antiox7120195 · Cited by 43

Extracellular matrix stiffness regulates mitochondrial dynamics through PINCH-1- and kindlin-2-mediated signalling

Chen, K., Wang, Y., Dèng, X., Guo, L., & Wu, C. (2021) · Current Research in Cell Biology · doi:10.1016/j.crcbio.2021.100008 · Cited by 42

Sustained intracellular calcium rise mediates neuronal mitophagy in models of autosomal dominant optic atrophy

Zaninello, M., Palikaras, K., Sotiriou, A., Tavernarakis, N., & Scorrano, L. (2021) · Cell Death and Differentiation · doi:10.1038/s41418-021-00847-3 · Cited by 40

Mff oligomerization is required for Drp1 activation and synergy with actin filaments during mitochondrial division

Liu, A., Kage, F., & Higgs, H. N. (2021) · Molecular Biology of the Cell · doi:10.1091/mbc.e21-04-0224 · Cited by 42

Formononetin Attenuates Renal Tubular Injury and Mitochondrial Damage in Diabetic Nephropathy Partly via Regulating Sirt1/PGC-1α Pathway

Huang, Q., Chen, H., Yin, K., Shen, Y., Lin, K., Guo, X., Zhang, X., Wang, N., Xin, W., Xu, Y., et al. (2022) · Frontiers in Pharmacology · doi:10.3389/fphar.2022.901234 · Cited by 43

PEX11β and FIS1 cooperate in peroxisome division independently of mitochondrial fission factor

Schrader, T. A., Carmichael, R. E., Islinger, M., Costello, J. L., Hacker, C., Bonekamp, N. A., Weishaupt, J. H., Andersen, P. M., & Schrader, M. (2022) · Journal of Cell Science · doi:10.1242/jcs.259924 · Cited by 39

Mitophagy in Huntington's disease

Šonský, I., Vodička, P., Kepková, K. V., & Hansíková, H. (2021) · Neurochemistry International · doi:10.1016/j.neuint.2021.105147 · Cited by 42

Mitochondrial Fusion and Fission in Neuronal Death Induced by Cerebral Ischemia-Reperfusion and Its Clinical Application: A Mini-Review

Chen, Y., Guo, S., Tang, Y., Mou, C., Hu, X., Shao, F., Yan, W. X., & Wu, Q. (2020) · Medical Science Monitor · doi:10.12659/msm.928651 · Cited by 42

Mitochondrial Fission Process 1 controls inner membrane integrity and protects against heart failure

Donnarumma, E., Kohlhaas, M., Vimont, E., Kornobis, É., Chaze, T., Gianetto, Q. G., Matondo, M., Moya‐Nilges, M., Maack, C., & Wai, T. (2022) · Nature Communications · doi:10.1038/s41467-022-34316-3 · Cited by 44

DRP1 mutations associated with EMPF1 encephalopathy alter mitochondrial membrane potential and metabolic programs

Robertson, G. L., Riffle, S., Patel, M., Bodnya, C., Marshall, A. G., Beasley, H. K., Lopez, E. G., Shao, J., Vue, Z., Hinton, A. O., Jr., et al. (2023) · Journal of Cell Science · doi:10.1242/jcs.260370 · Cited by 37

MiD49 and MiD51: New mediators of mitochondrial fission and novel targets for cardioprotection.

Samangouei, P., Crespo-Avilan, G. E., Cabrera-Fuentes, H. A., Hernández‐Reséndiz, S., Ismail, N. I., Katwadi, K., Boisvert, W. A., & Hausenloy, D. J. (2018) · PubMed · Cited by 38

Mind the Gap: Mitochondria and the Endoplasmic Reticulum in Neurodegenerative Diseases

Leal, N. S., & Martins, L. M. (2021) · Biomedicines · doi:10.3390/biomedicines9020227 · Cited by 40

Increased mitochondrial surface area and cristae density in the skeletal muscle of strength athletes

Botella, J., Schytz, C. T., Pehrson, T. F., Hokken, R., Laugesen, S., Aagaard, P., Suetta, C., Christensen, B., Ørtenblad, N., & Nielsen, J. (2023) · The Journal of Physiology · doi:10.1113/jp284394 · Cited by 40

Chemical inhibition of mitochondrial fission via targeting the DRP1-receptor interaction

Yang, J., Chen, P., Cao, Y., Liu, S., Wang, W., Li, L., Li, J., Jiang, Z., Ma, Y., Chen, S., et al. (2023) · Cell chemical biology · doi:10.1016/j.chembiol.2023.02.002 · Cited by 36

Mitochondrial fission – changing perspectives for future progress

Kamerkar, S. C., Liu, A., & Higgs, H. N. (2025) · Journal of Cell Science · doi:10.1242/jcs.263640 · Cited by 43

Cyclin C directly stimulates Drp1 GTP affinity to mediate stress-induced mitochondrial hyperfission

Ganesan, V., Willis, S. D., Chang, K., Beluch, S., Cooper, K. F., & Strich, R. (2018) · Molecular Biology of the Cell · doi:10.1091/mbc.e18-07-0463 · Cited by 36

Identification of Fis1 Interactors in Toxoplasma gondii Reveals a Novel Protein Required for Peripheral Distribution of the Mitochondrion

Jacobs, K., Charvat, R. A., & Arrizabalaga, G. (2020) · mBio · doi:10.1128/mbio.02732-19 · Cited by 35

Sitagliptin ameliorates renal tubular injury in diabetic kidney disease via STAT3‐dependent mitochondrial homeostasis through SDF‐1α/CXCR4 pathway

Zhang, Q., He, L. N., Dong, Y., Yang, F., Wen, J., Li, X., Guan, J., Liu, F., Zhou, T., Li, Z., et al. (2020) · The FASEB Journal · doi:10.1096/fj.201903038r · Cited by 35

Molecular wiring of a mitochondrial translational feedback loop

Salvatori, R., Kehrein, K., Singh, A. P., Aftab, W., Möller-Hergt, B. V., Forne, I., Imhof, A., & Ott, M. (2020) · Molecular Cell · doi:10.1016/j.molcel.2019.11.019 · Cited by 34

Emerging mechanistic insights of selective autophagy in hepatic diseases

Al‐Bari, M. A. A., Ito, Y., Thomes, P. G., Menon, M. B., Macia, M. G., Fadel, R. A., Stadlin, A., Peake, N., Faris, M. E., Eid, N. A. S., et al. (2023) · Frontiers in Pharmacology · doi:10.3389/fphar.2023.1149809 · Cited by 39

Molecular mechanisms of mammalian autophagy

Trelford, C. B., & Guglielmo, G. M. D. (2021) · Biochemical Journal · doi:10.1042/bcj20210314 · Cited by 35

Mid51/Fis1 mitochondrial oligomerization complex drives lysosomal untethering and network dynamics

Wong, Y. C., Kim, S., Cisneros, J., Molakal, C. G., Song, P., Lubbe, S. J., & Krainc, D. (2022) · The Journal of Cell Biology · doi:10.1083/jcb.202206140 · Cited by 33

Mouse Stbd1 is N-myristoylated and affects ER–mitochondria association and mitochondrial morphology

Demetriadou, A., Morales‐Sanfrutos, J., Nearchou, M., Baba, O., Kyriacou, K. C., Tate, E. W., Drousiotou, A., & Petrou, P. (2017) · Journal of Cell Science · doi:10.1242/jcs.195263 · Cited by 35

Fis1 ablation in the male germline disrupts mitochondrial morphology and mitophagy, and arrests spermatid maturation

Varuzhanyan, G., Ladinsky, M. S., Yamashita, S., Abe, M., Sakimura, K., Kanki, T., & Chan, D. C. (2021) · Development · doi:10.1242/dev.199686 · Cited by 31

Longitudinal metabolic profiling of cardiomyocytes derived from human-induced pluripotent stem cells

Bekhite, M. M., Delgado, A. G., Menz, F., Kretzschmar, T., Wu, J. M. F., Bekfani, T., Nietzsche, S., Wartenberg, M., Westermann, M., Greber, B., et al. (2020) · Basic Research in Cardiology · doi:10.1007/s00395-020-0796-0 · Cited by 31

Parallel kinase pathways stimulate actin polymerization at depolarized mitochondria

Fung, T. S., Chakrabarti, R., Kollasser, J., Rottner, K., Stradal, T. E. B., Kage, F., & Higgs, H. N. (2022) · Current Biology · doi:10.1016/j.cub.2022.02.058 · Cited by 35

Targeting mitochondrial dynamics and redox regulation in cardiovascular diseases

Beg, M. A., Huang, M., Vick, L., Rao, K. N. S., Zhang, J., & Chen, Y. (2024) · Trends in Pharmacological Sciences · doi:10.1016/j.tips.2024.02.001 · Cited by 31

New insights into vascular aging: Emerging role of mitochondria function

Li, Y., Jin, X., Li, D. X., Lu, J. Z., Zhang, X., Yang, S., Zhao, Y., & Wu, M. (2022) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2022.113954 · Cited by 30

SUMOylation of MFF coordinates fission complexes to promote stress-induced mitochondrial fragmentation

Seager, R., Ramesh, N. S., Cross, S., Guo, C., Wilkinson, K. A., & Henley, J. M. (2024) · Science Advances · doi:10.1126/sciadv.adq6223 · Cited by 32

Mitochondrial Dynamics: In Cell Reprogramming as It Is in Cancer

Prieto, J., & Torres, J. (2017) · Stem Cells International · doi:10.1155/2017/8073721 · Cited by 26

Mitochondrial Quality Control in the Maintenance of Cardiovascular Homeostasis: The Roles and Interregulation of UPS, Mitochondrial Dynamics and Mitophagy

Song, Y., Xu, Y., Liu, Y., Gao, J., Feng, L., Zhang, Y., Shi, L., Zhang, M., Guo, D., Qi, B., et al. (2021) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2021/3960773 · Cited by 27

Mitochondrial quality control in the brain: The physiological and pathological roles

Shen, X., Sun, P., Zhang, H., & Yang, H. (2022) · Frontiers in Neuroscience · doi:10.3389/fnins.2022.1075141 · Cited by 30

Rotaviral nonstructural protein 4 triggers dynamin-related protein 1-dependent mitochondrial fragmentation during infection

Mukherjee, A., Patra, U., Bhowmick, R., & Chawla‐Sarkar, M. (2018) · Cellular Microbiology · doi:10.1111/cmi.12831 · Cited by 29

Regulation of Mitochondrial Dynamics by Proteolytic Processing and Protein Turnover

Ali, S., & McStay, G. P. (2018) · Antioxidants · doi:10.3390/antiox7010015 · Cited by 29

A novel role for kynurenine 3-monooxygenase in mitochondrial dynamics

Maddison, D. C., Alfonso-Núñez, M., Swaih, A. M., Breda, C., Campesan, S., Allcock, N., Straatman-Iwanowska, A. A., Kyriacou, C. P., & Giorgini, F. (2020) · PLoS Genetics · doi:10.1371/journal.pgen.1009129 · Cited by 30

Acetylation in Mitochondria Dynamics and Neurodegeneration

Waddell, J., Banerjee, A., & Kristián, T. (2021) · Cells · doi:10.3390/cells10113031 · Cited by 27

Mitochondrial dynamics in neurological diseases: a narrative review

Shen, Y. G., Jiang, W., Li, X., Cao, A., Li, D. X., Li, S., Yang, J., & Jiao, Q. (2023) · Annals of Translational Medicine · doi:10.21037/atm-22-2401 · Cited by 26

Fatty acyl-coenzyme A activates mitochondrial division through oligomerization of MiD49 and MiD51

Liu, A., Kage, F., Abdulkareem, A. F., Aguirre-Huamani, M. P., Sapp, G., Aydin, H., & Higgs, H. N. (2024) · Nature Cell Biology · doi:10.1038/s41556-024-01400-3 · Cited by 29

Mitochondrial scenario: roles of mitochondrial dynamics in acute myocardial ischemia/reperfusion injury

Mui, D., & Zhang, Y. (2020) · Journal of Receptors and Signal Transduction · doi:10.1080/10799893.2020.1784938 · Cited by 27

Advances in Understanding Mitochondrial MicroRNAs (mitomiRs) on the Pathogenesis of Triple‐Negative Breast Cancer (TNBC)

Lin, H., & Chu, P. (2021) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2021/5517777 · Cited by 26

Mitochondrial fusion: Reaching the end of mitofusin’s tether

Formosa, L. E., & Ryan, M. T. (2016) · The Journal of Cell Biology · doi:10.1083/jcb.201611048 · Cited by 22

An emerging role of mitochondrial quality control in bone metabolism: from molecular mechanisms to targeted therapeutic interventions

Qin, Z., Zhu, X., Shen, Y., Ling, H., Ruan, N., Ye, W., Xu, Y., & Gan, X. (2025) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-025-05802-w · Cited by 25

Mitochondrial Dynamics in the Metabolic Memory of Diabetic Retinopathy

Mohammad, G., & Kowluru, R. A. (2022) · Journal of Diabetes Research · doi:10.1155/2022/3555889 · Cited by 24

Role of Mitochondrial Dynamics in Cocaine’s Neurotoxicity

Wen, S., Aki, T., Funakoshi, T., Unuma, K., & Uemura, K. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23105418 · Cited by 25

Mitochondrial Dysfunction, Mitophagy and Their Correlation with Perinatal Complications: Preeclampsia and Low Birth Weight

Yildirim, R. M., Ergun, Y., & Başar, M. (2022) · Biomedicines · doi:10.3390/biomedicines10102539 · Cited by 27

Structural studies of human fission protein FIS1 reveal a dynamic region important for GTPase DRP1 recruitment and mitochondrial fission

Egner, J. M., Nolden, K. A., Harwig, M. C., Bonate, R., de Anda, J., Tessmer, M. H., Noey, E. L., Ihenacho, U. K., Liu, Z., Peterson, F. C., et al. (2022) · Journal of Biological Chemistry · doi:10.1016/j.jbc.2022.102620 · Cited by 25

Mitochondrial behavior when things go wrong in the axon

Devoto, V. M. P., Onyango, I. G., & Stokin, G. B. (2022) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2022.959598 · Cited by 24

Three‐dimensional electron microscopy techniques for unravelling mitochondrial dysfunction in heart failure and identification of new pharmacological targets

Daghistani, H., Rajab, B. S., & Kitmitto, A. (2018) · British Journal of Pharmacology · doi:10.1111/bph.14499 · Cited by 22

Inhibitory effects of JQ1 on listeria monocytogenes-induced acute liver injury by blocking BRD4/RIPK1 axis

Qian, Z., Shuying, W., & Ranran, D. (2020) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2020.109818 · Cited by 22

Metabolic and mitochondria alterations induced by SARS‐CoV‐2 accessory proteins ORF3a, ORF9b, ORF9c and ORF10

López‐Ayllón, B. D., Marín, S., Fernández, M. F., García‐García, T., Fernández‐Rodríguez, R., de Lucas‐Rius, A., Redondo, N., Mendoza‐García, L., Foguet, C., Grigas, J., et al. (2024) · Journal of Medical Virology · doi:10.1002/jmv.29752 · Cited by 24

Exploring the Link Between Telomeres and Mitochondria: Mechanisms and Implications in Different Cell Types

Assalve, G., Lunetti, P., Rocca, M. S., Cosci, I., Nisio, A. D., Ferlin, A., Zara, V., & Ferramosca, A. (2025) · International Journal of Molecular Sciences · doi:10.3390/ijms26030993 · Cited by 24

A Disturbance in the Force: Cellular Stress Sensing by the Mitochondrial Network

Gilkerson, R. (2018) · Antioxidants · doi:10.3390/antiox7100126 · Cited by 22

Mitochondrial content is preserved throughout disease progression in the mdx mouse model of Duchenne muscular dystrophy, regardless of taurine supplementation

Barker, R. G., Wyckelsma, V. L., Xu, H., & Murphy, R. M. (2017) · American Journal of Physiology-Cell Physiology · doi:10.1152/ajpcell.00046.2017 · Cited by 20

Drp1: Focus on Diseases Triggered by the Mitochondrial Pathway

Sun, F., Fang, M., Zhang, H., Song, Q., Li, S., Li, Y., Jiang, S., & Yang, L. (2024) · Cell Biochemistry and Biophysics · doi:10.1007/s12013-024-01245-5 · Cited by 21

Inhibitors of Mitochondrial Dynamics Mediated by Dynamin-Related Protein 1 in Pulmonary Arterial Hypertension

Xiao, F., Zhang, R., & Wang, L. (2022) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2022.913904 · Cited by 19

miR‐376b‐3p attenuates mitochondrial fission and cardiac hypertrophy by targeting mitochondrial fission factor

Sun, Y. L., Li, S. H., Yang, L. J., & Wang, Y. (2018) · Clinical and Experimental Pharmacology and Physiology · doi:10.1111/1440-1681.12938 · Cited by 19

Characterization of the interactome of c-Src within the mitochondrial matrix by proximity-dependent biotin identification.

Guedouari, H., Amer, Y. O., Pichaud, N., & Hebert-Chatelain, E. (2021) · Mitochondrion (Amsterdam. Print) · doi:10.1016/j.mito.2020.12.012 · Cited by 17

Mitochondrial dynamics at the intersection of macrophage polarization and metabolism

Li, P., Fan, Z., Huang, Y., Luo, L., & Wu, X. (2025) · Frontiers in Immunology · doi:10.3389/fimmu.2025.1520814 · Cited by 23

Fission Impossible (?)—New Insights into Disorders of Peroxisome Dynamics

Carmichael, R. E., Islinger, M., & Schrader, M. (2022) · Cells · doi:10.3390/cells11121922 · Cited by 21

Hetero-oligomer of dynamin-related proteins participates in the fission of highly divergent mitochondria from Entamoeba histolytica

Makiuchi, T., Santos, H. J., Tachibana, H., & Nozaki, T. (2017) · Scientific Reports · doi:10.1038/s41598-017-13721-5 · Cited by 18

Mechanistic analysis of mitochondrial fission mediators

Singh, A. P. (2023) · Figshare · doi:10.26181/21844440

MiD51 and Mff Co-assemble in Cardiolipin-Enriched Membrane Microdomains to Cooperatively Regulate Drp1-Mediated Mitochondrial Fission

Macdonald, P. J., Stepanyants, N., Singh, A. P., Clinton, R. W., Osellame, L. D., Ryan, M. T., & Ramachandran, R. (2018) · Biophysical Journal · doi:10.1016/j.bpj.2017.11.3300 · Cited by 1

Adaptor Proteins MiD49 and MiD51 Can Act Independently of Mff and Fis1 in Drp1 Recruitment and Are Specific for Mitochondrial Fission

Palmer, C. S., Elgass, K. D., Parton, R. G., Osellame, L. D., Stojanovski, D., & Ryan, M. T. (2013) · Journal of Biological Chemistry · doi:10.1074/jbc.m113.479873 · Cited by 301

The role of Drp1 adaptor proteins MiD49 and MiD51 in mitochondrial fission: implications for human disease

Atkins, K., Dasgupta, A., Chen, K., Mewburn, J., & Archer, S. L. (2016) · Clinical Science · doi:10.1042/cs20160030 · Cited by 130

Fis1, Mff, MiD49, and MiD51 mediate Drp1 recruitment in mitochondrial fission

Losón, O. C., Song, Z., Chen, H., & Chan, D. C. (2013) · Molecular Biology of the Cell · doi:10.1091/mbc.e12-10-0721 · Cited by 1,235