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Taste discrimination in conditioned taste aversion of the pond snail Lymnaea stagnalis
Abstract
SUMMARY: Conditioned taste aversion (CTA) in the pond snail Lymnaea stagnalis has been widely used as a model for gaining an understanding of the molecular and behavioral mechanisms underlying learning and memory. At the behavioral level, however, it is still unclear how taste discrimination and CTA interact. We thus examined how CTA to one taste affected the feeding response induced by another appetitive food stimulus. We first demonstrated that snails have the capacity to recognize sucrose and carrot juice as distinct appetitive stimuli. We then found that snails can become conditioned(i.e. CTA) to avoid one of the stimuli and not the other. These results show that snails can distinguish between appetitive stimuli during CTA, suggesting that taste discrimination is processed upstream of the site where memory consolidation in the snail brain occurs. Moreover, we examined second-order conditioning with two appetitive stimuli and one aversive stimulus. Snails acquired second-order conditioning and were still able to distinguish between the different stimuli. Finally, we repeatedly presented the conditional stimulus alone to the conditioned snails, but this procedure did not extinguish the long-term memory of CTA in the snails. Taken together, our data suggest that CTA causes specific, irreversible and rigid changes from appetitive stimuli to aversive ones in the conditioning procedure.
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“and in the pond snail Lymnaea stagnalis second order conditioning of simple taste discrimination was observed (Sugai et al. 2006; for more tests see Benjamin and Kemenes 2010)”
From Unlimited Associative Learning and the origins of consciousness: a primer and some predictions (2020) · cites this paper as Sugai et al. 2006
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Unlimited Associative Learning and the origins of consciousness: a primer and some predictions
Birch, J., Ginsburg, S., & Jablonka, E. (2020) · Biology & Philosophy · doi:10.1007/s10539-020-09772-0 · Cited by 149
“For example, gastropod molluscs show rapid avoidance learning (Siegel and Jarvik 1974), and in the pond snail Lymnaea stagnalis second order conditioning of simple taste discrimination was observed (Sugai et al. 2006; for more tests see Benjamin and Kemenes 2010), but we are not aware of experiments testing for discri…”
Background
Metadata
- Authors
- Sugai, R., Shiga, H., Azami, S., Watanabe, T., Sadamoto, H., Fujito, Y., Lukowiak, K., & Ito, E.
- Affiliations
- Hokkaido University (JP)
- Sapporo Medical University (JP)
- University of Calgary (CA)
- Corresponding author
- Ito, Etsuro
- Venue
- Journal of Experimental Biology
- Publisher
- The Company of Biologists
- Published
- 2006-03-01
- Volume
- 209
- Issue
- 5
- Pages
- 826-833
- ISSN
- 0022-0949 (ISSN-L)
- 1477-9145
- OpenAlex
- W2149412668
- Cited by
- 57
- References
- 44
- Citations by year
- 2026: 1 · 2025: 1 · 2024: 3 · 2023: 3 · 2022: 2 · 2021: 4 · 2020: 4 · 2019: 3 · 2018: 1 · 2017: 3 · 2016: 2 · 2015: 3 · 2014: 2 · 2013: 8 · 2012: 1
- FWCI
- 1.94
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Experimental Biology (publishedVersion)
- PubMed (publishedVersion)
- HighWire Press Open Archive (submittedVersion)
- Topics
- Life Sciences › Neuroscience › Cognitive Neuroscience › Memory and Neural Mechanisms
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neurobiology and Insect Physiology Research
- Life Sciences › Agricultural and Biological Sciences › Animal Science and Zoology › Mollusks and Parasites Studies
- Keywords
- conditioned taste aversion, Lymnaea stagnalis, taste discrimination, second-order conditioning, appetitive stimuli, memory consolidation, learning and memory, memory extinction, feeding behavior, sucrose, carrot juice
- MeSH terms
- Animals, Conditioning, Psychological, Lymnaea, Taste, Time Factors
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