Studies on ergothioneine. V. Determination by high performance liquid chromatography and application to metabolic research.
Open accessAbstract
The high performance liquid chromatographic procedure was established for the determination of ergothioneine in biological materials. The procedure is also applicable to the purification of 3H-ergothioneine. The metabolism of ergothioneine given to rats was very slow ; the ergothioneine was not disappear even after 1 week fasting. The ergothioneine administrated was mostly concentrated in the liver and the level was 10 times as high as that in blood. All ergothioneine in the blood was found in blood corpuscles 24 hr after the administration.
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ERG is metabolised and excreted only slowly.
“ERG is metabolised and excreted only slowly(360,371,401,402).”
From The biology of ergothioneine, an antioxidant nutraceutical (2020) · cites this paper as [371]
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Cited by 50
- Authors
- MAYUMI, T., KAWANO, H., SAKAMOTO, Y., SUEHISA, E., KAWAI, Y., & HAMA, T.
- Affiliations
- Kobe Gakuin University (JP)
- ORCID
- SAKAMOTO, YOSHIKO
- Venue
- Chemical and Pharmaceutical Bulletin
- Publisher
- Pharmaceutical Society of Japan
- Published
- 1978
- Volume
- 26
- Issue
- 12
- Pages
- 3772-3778
- ISSN
- 0009-2363 (ISSN-L)
- 1347-5223
- OpenAlex
- W1512368457
- Cited by
- 50
- References
- 0
- Citations by year
- 2026: 1 · 2025: 3 · 2024: 4 · 2023: 1 · 2022: 2 · 2021: 1 · 2020: 4 · 2018: 1 · 2017: 1 · 2016: 3 · 2015: 1 · 2014: 3 · 2013: 4 · 2012: 3
- FWCI
- 0.00
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Chemical and Pharmaceutical Bulletin (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Biochemistry › Sulfur Compounds in Biology
- Physical Sciences › Chemistry › Analytical Chemistry › Analytical Methods in Pharmaceuticals
- Physical Sciences › Chemistry › Spectroscopy › Analytical Chemistry and Chromatography
- Keywords
- ergothioneine, HPLC assay, tissue distribution, liver, blood corpuscles, rats
- MeSH terms
- Animals, Chromatography, High Pressure Liquid, Ergothioneine, Tissue Distribution, Rats
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