Skeletal Muscle Hypertrophy After Aerobic Exercise Training
Open accessAbstract
In Brief Current dogma suggests that aerobic exercise training has minimal effects on skeletal muscle size. We and others have demonstrated that aerobic exercise acutely and chronically alters protein metabolism and induces skeletal muscle hypertrophy. These findings promote an antithesis to the status quo by providing novel perspective on skeletal muscle mass regulation and insight into exercise countermeasures for populations prone to muscle loss. Although not commonly associated with gains in skeletal muscle mass, aerobic exercise stimulates muscle protein synthesis and skeletal muscle hypertrophy.
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Aerobic exercise training can lead to skeletal muscle hypertrophy.
“It has also been shown that aerobic exercise training can lead to skeletal muscle hypertrophy.146”
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References 41 · Cited by 320
- Authors
- Konopka, A. R., & Harber, M. P.
- Affiliations
- Mayo Clinic (US)
- Taylor University (US)
- Corresponding author
- Harber, Matthew P.
- Venue
- Exercise and Sport Sciences Reviews
- Published
- 2014-04
- Volume
- 42
- Issue
- 2
- Pages
- 53-61
- ISSN
- 0091-6331 (ISSN-L)
- PMC
- PMC4523889
- OpenAlex
- W2001770100
- Cited by
- 320
- References
- 41
- Citations by year
- 2026: 20 · 2025: 35 · 2024: 37 · 2023: 35 · 2022: 36 · 2021: 30 · 2020: 27 · 2019: 31 · 2018: 31 · 2017: 13 · 2016: 12 · 2015: 8 · 2014: 5
- FWCI
- 1.27
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Exercise and Sport Sciences Reviews (publishedVersion)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- Funders
- National Aeronautics and Space Administration
- National Institutes of Health
- National Institute on Aging (AG032127, R15AG032127)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Cell Biology › Muscle metabolism and nutrition
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Muscle Physiology and Disorders
- Health Sciences › Medicine › Complementary and alternative medicine › Cardiovascular and exercise physiology
- Keywords
- skeletal muscle hypertrophy, aerobic exercise training, muscle protein synthesis, muscle protein metabolism, muscle mass regulation, sarcopenia, exercise countermeasures
- MeSH terms
- Adaptation, Physiological, Aging, Humans, Mitochondria, Muscle, Muscle Proteins, Exercise, Muscle, Skeletal, Muscle Fibers, Skeletal, Resistance Training
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