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The DOI matches its Crossref record; 38 of the 38 references it cites were found in a registry or an index.

Benefits of Resistance Training with Blood Flow Restriction in Knee Osteoarthritis

FERRAZ, RODRIGO BRANCO, GUALANO, BRUNO, RODRIGUES, REYNALDO, KURIMORI, CECI OBARA, FULLER, RICARDO, LIMA, FERNANDA RODRIGUES, DE SÁ-PINTO, ANA LÚCIA, ROSCHEL, HAMILTON·2018·Medicine & Science in Sports & Exercise

Abstract

PURPOSE: Evaluate the effects of a low-intensity resistance training (LI-RT) program associated with partial blood flow restriction on selected clinical outcomes in patients with knee osteoarthritis (OA). METHODS: Forty-eight women with knee OA were randomized into one of the three groups: LI-RT (30% one repetition maximum [1-RM]) associated (blood flow restriction training [BFRT]) or not (LI-RT) with partial blood flow restriction, and high-intensity resistance training (HI-RT, 80% 1-RM). Patients underwent a 12-wk supervised training program and were assessed for lower-limb 1-RM, quadriceps cross-sectional area, functionality (timed-stands test and timed-up-and-go test), and disease-specific inventory (Western Ontario and McMaster Universities Osteoarthritis Index [WOMAC]) before (PRE) and after (POST) the protocol. RESULTS: Similar within-group increases were observed in leg press (26% and 33%, all P < 0.0001), knee extension 1-RM (23% and 22%; all P < 0.0001) and cross-sectional area (7% and 8%; all P < 0.0001) in BFRT and HI-RT, respectively, and these were significantly greater (all P < 0.05) than those of LI-RT. The BFRT and HI-RT showed comparable improvements in timed-stands test (7% and 14%, respectively), with the latter showing greater increases than LI-RT. Timed-up-and-go test scores were not significantly changed within or between groups. WOMAC physical function was improved in BFRT and HI-RT (-49% and -42%, respectively; all P < 0.05), and WOMAC pain was improved in BFRT and LI-RT (-45% and -39%, respectively; all P < 0.05). Four patients (of 16) were excluded due to exercise-induced knee pain in HI-RT. CONCLUSIONS: Blood flow restriction training and HI-RT were similarly effective in increasing muscle strength, quadriceps muscle mass, and functionality in knee OA patients. Importantly, BFRT was also able to improve pain while inducing less joint stress, emerging as a feasible and effective therapeutic adjuvant in OA management.

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Metadata

Authors
FERRAZ, R. B., GUALANO, B., RODRIGUES, R., KURIMORI, C. O., FULLER, R., LIMA, F. R., DE SÁ-PINTO, A. L., & ROSCHEL, H.
Venue
Medicine & Science in Sports & Exercise
Published
2018-05
Volume
50
Issue
5
Pages
897-905
ISSN
0195-9131 (ISSN-L)
OpenAlex
W2779346074
Cited by
256
References
38
FWCI
20.60
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Benefits of Resistance Training with Blood Flow Restriction in Knee Osteoarthritis. https://app.cochat.ai/papers/10.1249/mss.0000000000001530
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FERRAZ, R. B., GUALANO, B., RODRIGUES, R., KURIMORI, C. O., FULLER, R., LIMA, F. R., DE SÁ-PINTO, A. L., & ROSCHEL, H. (2018). Benefits of Resistance Training with Blood Flow Restriction in Knee Osteoarthritis. Medicine & Science in Sports & Exercise. https://doi.org/10.1249/mss.0000000000001530

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