Usefulness of magnetocardiography to detect coronary artery disease and cardiac allograft vasculopathy
Open accessAbstract
BACKGROUND: Electrophysiological information as well as anatomic information are important for the detection of coronary artery lesions. The aim of this study was to assess the efficacy of resting magnetocardiography (MCG) in stable coronary artery disease (CAD) and cardiac allograft vasculopathy (CAV). METHODS AND RESULTS: MCG and coronary angiography were performed within 1 month in 75 patients with suspected CAD and in 26 subjects after orthotopic heart transplantation (OHT). Plaque volumes were additionally measured on intravascular ultrasound in OHT recipients. The spatially distributed QT(c) interval maps were constructed with 64-channel MCG. A T-wave propagation map and QT(c) heterogeneity index including QT(c) dispersion and smoothness index of QT(c) (SI-QT(c)) were derived for ischemia detection and localization. CAD patients had higher QT(c) dispersion and SI-QT(c). Receiver operating characteristic curve analysis identified SI-QT(c) ≥9 ms, QT(c) dispersion ≥79 ms as the optimal cut-off for detecting CAD (diagnostic accuracy, 0.7953, 0.7819), better than T-wave propagation (0.6594, P<0.05). There was no significant difference of QT(c) dispersion between CAD and OHT subjects. In OHT recipients, QT(c) dispersion positively correlated with plaque volume, and SI-QT(c) progressively increased after transplantation. Using T-wave propagation mapping, regionally increased dispersion could be demonstrated in CAD patients, but increased dispersion was noted in fewer OHT recipients. CONCLUSIONS: MCG is clinically feasible as a non-invasive tool for diagnosis of CAD, and could be used as a surrogate marker of CAV.
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Parallel research efforts with shielded and unshielded MCG over the last three decades have provided evidence of well-defined fields of clinical application, such as emergency triage of chest pain, diagnosis of ischemic and non-ischemic cardiomyopathies, heart transplant rejection, non-invasive 3D EAI of arrhythmogenic substrates and mechanisms, fetal MCG, and prenatal diagnosis of arrhythmogenicリ
“provided evidence of well-defined fields of clinical application, such as the emergency triage of patients with chest pain, the diagnosis of different kinds of ischemic and non-ischemic cardiomyopathies, the heart transplant rejection (80, 81), the non-invasive 3D EAI of arrhythmogenic substrates and mechanisms (82), fetal MCG, and in particular the prenatal diagnosis of arrhythmogenic risk and”
From Clinical magnetocardiography: the unshielded bet—past, present, and future (2023) · cites this paper as [81]
Split into 2 atoms — 0 confirmed, 0 partially supported, 2 disputed, 0 misattributed, 0 unverifiable. Expand the claim to see per-atom verdicts.
Checked by a reasoning model — may be wrong.
Experimental — accuracy not yet measured
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
The citation lists haven’t been fetched yet
References 40 · Cited by 18
Research works printed but not linked: 5
- Oh JK, Seward JB, Tajik AJ. The echo manual, 3rd edn. Philadel- phia: Lippincott Williams & Wilkins, 2007.
- Weiss JN, Chen PS, Qu Z, Karagueuzian HS, Garfinkel A. Ventricu- lar fibrillation: How do we stop the waves from breaking? Circ Res 2000; 87: 1103 -1107.
- Kolasa MW, Lee JC, Atwood JE, Marcus RR, Eckart RE. Relation of QTc duration heterogeneity to mortality following orthotopic heart transplantation. Am J Cardiol 2005; 95: 431 -432.
- Lee CM, Wu YW, Jui HY, Yen RF, Tzen KY, Chou NK, et al. In- travascular ultrasound correlates with coronary flow reserve and pre- dicts the survival in angiographically silent cardiac transplant recipi- ents. Cardiology 2008; 109: 93 -98.
- Wu YW, Chen YH, Wang SS, Jui HY, Yen RF, Tzen KY, et al. Myo- cardial perfusion reserve by positron emission tomography inversely correlates with intravascular ultrasound in angiographically normal cardiac transplant recipients. J Nucl Med 2010; 51: 906 -912.
- Authors
- Wu, Y.-W., Lee, C.-M., Liu, Y.-B., Wang, S.-S., Huang, H.-C., Tseng, W.-K., Jui, H.-Y., Wang, S.-Y., Horng, H.-E., Yang, H.-C., & Wu, C.-C.
- Affiliations
- Far Eastern Memorial Hospital (TW)
- Department of Internal Medicine (Cardiology Division), National Taiwan University Hospital
- National Taiwan University Hospital (TW)
- E-Da Hospital (TW)
- National Taiwan Normal University (TW)
- National Taiwan University (TW)
- Venue
- Circulation Journal
- Publisher
- Japanese Circulation Society
- Published
- 2013
- Volume
- 77
- Issue
- 7
- Pages
- 1783-1790
- ISSN
- 1346-9843 (ISSN-L)
- 1347-4820
- OpenAlex
- W2004693809
- Cited by
- 18
- References
- 40
- Citations by year
- 2026: 1 · 2025: 2 · 2024: 2 · 2023: 2 · 2022: 2 · 2020: 1 · 2019: 1 · 2017: 2 · 2016: 1 · 2015: 2 · 2014: 2
- FWCI
- 1.14
- Type
- journal article
- Language
- en
- Open access
- diamond
- doi.org
- Locations
- Circulation Journal (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Science Council
- Topics
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › ECG Monitoring and Analysis
- Health Sciences › Medicine › Radiology, Nuclear Medicine and Imaging › Cardiac Imaging and Diagnostics
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac electrophysiology and arrhythmias
- Keywords
- magnetocardiography, coronary artery disease, cardiac allograft vasculopathy, QTc dispersion, myocardial ischemia detection, heart transplantation, coronary plaque volume, non-invasive diagnosis
- MeSH terms
- Aged, Coronary Artery Disease, Coronary Vessels, Echocardiography, Female, Humans, Male, Middle Aged, Heart Transplantation, Magnetocardiography, Allografts
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
