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Cited by 11Gestational Diabetes Research and ManagementDiabetes Management and ResearchDiabetes, Cardiovascular Risks, and Lipoproteins

High proportion of overt diabetes mellitus in pregnancy and missed opportunity for early detection of diabetes at a tertiary care centre in Pakistan

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Wali, Aisha Syed, Rafique, Raheela, Iftikhar, Sundus, Ambreen, Rakhshinda, Yakoob, Mohammad Yawar·2019·Pakistan Journal of Medical Sciences
DOI 10.12669/pjms.36.icon-suppl.1723PMC PMC6943103
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Abstract

Objectives: To determine the frequency of diabetes in pregnancy (DIP), namely pre-gestational, gestational (GDM) and overt diabetes mellitus (DM) in women registered for delivery. Methods: A retrospective chart review of antenatal women registered between January 01 to August 31, 2017 was performed. Gestational age, diagnosis of DIP, glucose levels at diagnosis and other relevant data was extracted. The effect of various fasting blood glucose (FBG) thresholds for diagnosis of DIP was assessed. Results: DIP was diagnosed in 21.8% women (pre-gestational: 2%, GDM: 81.2%, overt DM: 16.8%). In early registrants, 30.2% were detected through screening. However, 55.3% of women registered late. Women with pre-gestational DM were older, had more miscarriages, and greater personal and family history of diabetes versus GDM and overt DM. Raising the diagnostic threshold of FBG from 92 mg/dl to 95 mg/dl missed three women (0.1%) and to 105 mg/dl, missed six women (0.2%). Conclusion: We observed a high proportion of overt DM. In early registrants, almost one third of DIP was diagnosed in the first half of pregnancy, an opportunity missed in late registrants. Altering diagnostic thresholds of DIP affected only a small proportion of women. doi: https://doi.org/10.12669/pjms.36.ICON-Suppl.1723 How to cite this:Wali AS, Rafique R, Iftikhar S, Ambreen R, Yakoob MY. High proportion of overt diabetes mellitus in pregnancy and missed opportunity for early detection of diabetes at a tertiary care centre in Pakistan. Pak J Med Sci. Special Supplement ICON 2020. 2020;36(1):S38-S43. doi: https://doi.org/10.12669/pjms.36.ICON-Suppl.1723 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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  • In Pakistan, between January and August 2017, Wali et al. conducted a study and 21.8% of pregnant women were diagnosed with GDM.

    “Between January and August 2017 Wali et al. conducted a study with the main goal of assessing the prevalence of GDM and 21.8% of pregnant women were diagnosed with GDM [219].”

    From Evolution of Gestational Diabetes Mellitus across Continents in 21st Century (2022) · cites this paper as [219]

    The Abstract Methods describe a review of women registered from January 1 to August 31, 2017, supporting the timeframe. The Results report that 21.8% had diabetes in pregnancy, but only 17.8% of screened women had GDM; the claim incorrectly labels the 21.8% figure as GDM. (LLM, conf=0.91)

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Research works printed but not linked: 22

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Sorted by citations

Authors
Wali, A. S., Rafique, R., Iftikhar, S., Ambreen, R., & Yakoob, M. Y.
Affiliations
Indus Hospital (PK)
Corresponding author
Wali, Aisha Syed
ORCID
Venue
Pakistan Journal of Medical Sciences
Publisher
Pakistan Journal of Medical Sciences
Published
2019-11-28
Volume
36
Issue
1
Pages
S38-S43
ISSN
  • 1681-715X (ISSN-L)
  • 1682-024X
DOI
10.12669/pjms.36.icon-suppl.1723
PMC
PMC6943103
OpenAlex
W2990347260
Cited by
11
References
0
Citations by year
2026: 1 · 2025: 1 · 2024: 3 · 2023: 1 · 2022: 3 · 2021: 2
FWCI
1.36
Type
journal article
Language
en
Open access
Licence
cc-by
Locations
  • Pakistan Journal of Medical Sciences (publishedVersion, cc-by)
  • Europe PMC (PubMed Central) (publishedVersion, cc-by)
  • PubMed Central (publishedVersion, cc-by)
  • PubMed (publishedVersion)
Funders
Indus Hospital
Topics
  • Health Sciences › Medicine › Obstetrics and Gynecology › Gestational Diabetes Research and Management
  • Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Management and Research
  • Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes, Cardiovascular Risks, and Lipoproteins
Keywords
diabetes in pregnancy, gestational diabetes mellitus, pregestational diabetes, prenatal screening, late registration

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