The DOI matches its Crossref record; 25 of the 25 references it cites were found in a registry or an index.
Long-Term Effects of Traffic-Related Air Pollution on Mortality in a Dutch Cohort (NLCS-AIR Study)
Open accessAbstract
BACKGROUND: Several studies have found an effect on mortality of between-city contrasts in long-term exposure to air pollution. The effect of within-city contrasts is still poorly understood. OBJECTIVES: We studied the association between long-term exposure to traffic-related air pollution and mortality in a Dutch cohort. METHODS: We used data from an ongoing cohort study on diet and cancer with 120,852 subjects who were followed from 1987 to 1996. Exposure to black smoke (BS), nitrogen dioxide, sulfur dioxide, and particulate matter < or = 2.5 microm (PM(2.5)), as well as various exposure variables related to traffic, were estimated at the home address. We conducted Cox analyses in the full cohort adjusting for age, sex, smoking, and area-level socioeconomic status. RESULTS: Traffic intensity on the nearest road was independently associated with mortality. Relative risks (95% confidence intervals) for a 10-microg/m(3) increase in BS concentrations (difference between 5th and 95th percentile) were 1.05 (1.00-1.11) for natural cause, 1.04 (0.95-1.13) for cardiovascular, 1.22 (0.99-1.50) for respiratory, 1.03 (0.88-1.20) for lung cancer, and 1.04 (0.97-1.12) for mortality other than cardiovascular, respiratory, or lung cancer. Results were similar for NO(2) and PM(2.5), but no associations were found for SO(2). CONCLUSIONS: Traffic-related air pollution and several traffic exposure variables were associated with mortality in the full cohort. Relative risks were generally small. Associations between natural-cause and respiratory mortality were statistically significant for NO(2) and BS. These results add to the evidence that long-term exposure to ambient air pollution is associated with increased mortality.
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Cites
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Cited by
Brook, R. D., Rajagopalan, S., Pope, C. A., Brook, J. R., Bhatnagar, A., Diez-Roux, A. V., Holguin, F., Hong, Y., Luepker, R. V., Mittleman, M. A., et al. (2010) · Circulation · doi:10.1161/cir.0b013e3181dbece1 · Cited by 6,548
Global estimates of mortality associated with long-term exposure to outdoor fine particulate matter
Burnett, R., Chen, H., Szyszkowicz, M., Fann, N., Hubbell, B., Pope, C. A., Apte, J. S., Brauer, M., Cohen, A., Weichenthal, S., et al. (2018) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1803222115 · Cited by 2,504
Self-citationChen, J., & Hoek, G. (2020) · Environment International · doi:10.1016/j.envint.2020.105974 · Cited by 1,042
Self-citationLepeule, J., Laden, F., Dockery, D., & Schwartz, J. (2012) · Environmental Health Perspectives · doi:10.1289/ehp.1104660 · Cited by 983
Air pollutants, oxidative stress and human health
Yang, W., & Omaye, S. T. (2009) · Mutation Research/Genetic Toxicology and Environmental Mutagenesis · doi:10.1016/j.mrgentox.2008.10.005 · Cited by 326
Metadata
- Authors
- Beelen, R., Hoek, G., van den Brandt, P. A., Goldbohm, R. A., Fischer, P., Schouten, L. J., Jerrett, M., Hughes, E., Armstrong, B., & Brunekreef, B.
- Venue
- Environmental Health Perspectives
- Publisher
- American Chemical Society (ACS)
- Published
- 2008-02
- Volume
- 116
- Issue
- 2
- Pages
- 196-202
- ISSN
- 0091-6765 (ISSN-L)
- 1552-9924
- OpenAlex
- W2064129615
- Cited by
- 601
- References
- 25
- FWCI
- 18.23
- Type
- journal article
- Language
- en
- Open access
- gold
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- Beelen, R., Hoek, G., van den Brandt, P. A., Goldbohm, R. A., Fischer, P., Schouten, L. J., Jerrett, M., Hughes, E., Armstrong, B., & Brunekreef, B. (2008). Long-Term Effects of Traffic-Related Air Pollution on Mortality in a Dutch Cohort (NLCS-AIR Study). Environmental Health Perspectives. https://doi.org/10.1289/ehp.10767
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