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Cited by 601

The DOI matches its Crossref record; 25 of the 25 references it cites were found in a registry or an index.

Long-Term Effects of Traffic-Related Air Pollution on Mortality in a Dutch Cohort (NLCS-AIR Study)

Open access
Beelen, Rob, Hoek, Gerard, van den Brandt, Piet A., Goldbohm, R. Alexandra, Fischer, Paul, Schouten, Leo J., Jerrett, Michael, Hughes, Edward, Armstrong, Ben, Brunekreef, Bert·2008·Environmental Health Perspectives

Abstract

BACKGROUND: Several studies have found an effect on mortality of between-city contrasts in long-term exposure to air pollution. The effect of within-city contrasts is still poorly understood. OBJECTIVES: We studied the association between long-term exposure to traffic-related air pollution and mortality in a Dutch cohort. METHODS: We used data from an ongoing cohort study on diet and cancer with 120,852 subjects who were followed from 1987 to 1996. Exposure to black smoke (BS), nitrogen dioxide, sulfur dioxide, and particulate matter < or = 2.5 microm (PM(2.5)), as well as various exposure variables related to traffic, were estimated at the home address. We conducted Cox analyses in the full cohort adjusting for age, sex, smoking, and area-level socioeconomic status. RESULTS: Traffic intensity on the nearest road was independently associated with mortality. Relative risks (95% confidence intervals) for a 10-microg/m(3) increase in BS concentrations (difference between 5th and 95th percentile) were 1.05 (1.00-1.11) for natural cause, 1.04 (0.95-1.13) for cardiovascular, 1.22 (0.99-1.50) for respiratory, 1.03 (0.88-1.20) for lung cancer, and 1.04 (0.97-1.12) for mortality other than cardiovascular, respiratory, or lung cancer. Results were similar for NO(2) and PM(2.5), but no associations were found for SO(2). CONCLUSIONS: Traffic-related air pollution and several traffic exposure variables were associated with mortality in the full cohort. Relative risks were generally small. Associations between natural-cause and respiratory mortality were statistically significant for NO(2) and BS. These results add to the evidence that long-term exposure to ambient air pollution is associated with increased mortality.

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Metadata

Authors
Beelen, R., Hoek, G., van den Brandt, P. A., Goldbohm, R. A., Fischer, P., Schouten, L. J., Jerrett, M., Hughes, E., Armstrong, B., & Brunekreef, B.
Venue
Environmental Health Perspectives
Published
2008-02
Volume
116
Issue
2
Pages
196-202
ISSN
  • 0091-6765 (ISSN-L)
  • 1552-9924
OpenAlex
W2064129615
Cited by
601
References
25
FWCI
18.23
Type
journal article
Language
en
Open access
gold

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Beelen, R., Hoek, G., van den Brandt, P. A., Goldbohm, R. A., Fischer, P., Schouten, L. J., Jerrett, M., Hughes, E., Armstrong, B., & Brunekreef, B. (2008). Long-Term Effects of Traffic-Related Air Pollution on Mortality in a Dutch Cohort (NLCS-AIR Study). Environmental Health Perspectives. https://doi.org/10.1289/ehp.10767

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