Effect of a low glycemic diet in patients with polycystic ovary syndrome and anovulation - a randomized controlled trial
Open accessAbstract
OBJECTIVE: To determine whether a low glycemic index diet is better than a normal glycemic index diet in producing ovulatory cycles in women with polycystic ovary syndrome (PCOS) and anovulation. MATERIALS AND METHODS: A randomized controlled clinical trial involving 37 women with PCOS and anovulation. The authors randomly assigned low glycemic index diets (n = 19) and normal glycemic index (n = 18) diets, and analyzed the number of ovulatory cycles for three months. RESULTS: In patients who consumed a low glycemic index diet, 24.6% (14/57) of the cycles were ovulatory. In those who consumed a normal glycemic index diet, only 7.4% (4/54) of the cycles were ovulatory (p = 0.014). CONCLUSIONS: The difference observed in the number of ovulatory cycles could be related to a decrease in the serum levels of circulating androgens, secondary to an improvement in insulin resistance.
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Low-GI diets have been demonstrated to increase ovulation and decrease anovulation in PCOS patients.
“Low-GI diets have also been demonstrated to increase ovulation and decrease anovulation in PCOS patients [52].”
From Role of Omega-3 Fatty Acids in Improving Metabolic Dysfunctions in Polycystic Ovary Syndrome (2024) · cites this paper as [52]
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The Role of Lifestyle Interventions in PCOS Management: A Systematic Review
Gautam, R., Maan, P., Jyoti, A., Kumar, A., Malhotra, N., & Arora, T. (2025) · Nutrients · doi:10.3390/nu17020310 · Cited by 115 · see citing works
Juhász, A. E., Stubnya, M. P., Teutsch, B., Gede, N., Hegyi, P., Nyirády, P., Bánhidy, F., Ács, N., & Juhász, R. (2024) · Reproductive Health · doi:10.1186/s12978-024-01758-5 · Cited by 32 · see citing works
Role of Omega-3 Fatty Acids in Improving Metabolic Dysfunctions in Polycystic Ovary Syndrome
Albardan, L., Platat, C., & Kalupahana, N. S. (2024) · Nutrients · doi:10.3390/nu16172961 · Cited by 18 · see citing works
“Low-GI diets have also been demonstrated to increase ovulation and decrease anovulation in PCOS patients [52].”
Background
- Authors
- Sordia-Hernández, L. H. S.-H., Rodríguez, P. A. R., Rodriguez, D. S., Guzmán, S. T. G., Zenteno, E. S. S., González, G. G. G., & Patiño, R. I. P.
- Affiliations
- Universidad Autónoma de Nuevo León (MX)
- Venue
- Clinical and Experimental Obstetrics & Gynecology
- Publisher
- IMR Press
- Published
- 2016-08-10
- Volume
- 43
- Issue
- 4
- Pages
- 555-559
- ISSN
- 0390-6663 (ISSN-L)
- OpenAlex
- W3025538917
- Cited by
- 21
- References
- 0
- Citations by year
- 2026: 3 · 2025: 3 · 2024: 5 · 2023: 1 · 2022: 1 · 2021: 5 · 2020: 2 · 2019: 1
- FWCI
- 0.44
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Clinical and Experimental Obstetrics & Gynecology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Reproductive Medicine › Ovarian function and disorders
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes, Cardiovascular Risks, and Lipoproteins
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diet, Metabolism, and Disease
- Keywords
- polycystic ovary syndrome, anovulation, low glycemic index diet, ovulation induction, insulin resistance, androgen levels, dietary intervention
- MeSH terms
- Glycemic Load, Adult, Androgens, Anovulation, Diet, Female, Humans, Insulin Resistance, Polycystic Ovary Syndrome, Glycemic Index, Young Adult
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