A review of research examining the regulatory role of lymphocytes in normal wound healing
Abstract
Lymphocytes play a distinct, regulatory role in normal wound healing through the secretion of lymphokines. This paper evaluates the current research on the regulatory role of lymphocytes and their secretions in normal wound healing.
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T lymphocytes play an important late regulatory role in resolving inflammation through local secretion of cytokines/chemokines that affect macrophage polarization.
“The T lymphocyte population also plays an important late regulatory role in the resolution of the inflammatory process through local secretion of cytokines and chemokines, many of which are known to affect macrophage polarization [97].”
From Macrophage polarization: an opportunity for improved outcomes in biomaterials and regenerative medicine (2012) · cites this paper as [97]
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Brown, B. N., Ratner, B. D., Goodman, S. B., Amar, S., & Badylak, S. F. (2012) · Biomaterials · doi:10.1016/j.biomaterials.2012.02.034 · Cited by 926 · see citing works
“The T lymphocyte population also plays an important late regulatory role in the resolution of the inflammatory process through local secretion of cytokines and chemokines, many of which are known to affect macrophage polarization [97].”
Background
- Authors
- Keen, D.
- Affiliations
- Carmarthenshire NHS Trust, Wales, UK
- Corresponding author
- Keen, D.
- Venue
- Journal of Wound Care
- Publisher
- Mark Allen Group
- Published
- 2008-05
- Volume
- 17
- Issue
- 5
- Pages
- 218-220
- ISSN
- 0969-0700 (ISSN-L)
- 2052-2916
- OpenAlex
- W2320715000
- Cited by
- 21
- References
- 0
- Citations by year
- 2024: 1 · 2020: 2 · 2018: 2 · 2017: 1 · 2016: 1 · 2015: 1 · 2013: 7 · 2012: 4
- FWCI
- 0.71
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Wound Care (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Rehabilitation › Wound Healing and Treatments
- Health Sciences › Medicine › Hepatology › Liver physiology and pathology
- Life Sciences › Immunology and Microbiology › Immunology › T-cell and B-cell Immunology
- Keywords
- lymphocytes, wound healing, lymphokines, lymphocyte regulation, cytokines
- MeSH terms
- Humans, Lymphocytes, Lymphokines, T-Lymphocytes, Wound Healing, Up-Regulation
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