The DOI matches its Crossref record.
Release of prostaglandins from bone and muscle after tibial fracture. An experimental study in rabbits
Abstract
The release of prostaglandins E and F from the tibiae of rabbits and the surrounding muscle in vitro after fracture and pinning, or pinning alone, has been compared to the release from unoperated tissues. The fractured tibiae released significantly more prostaglandins E and F than the control tibiae three to 14 days after operation. The pinned tibiae also released more of the two prostaglandins, although this was significant only after 14 days. Consequently it was only around the third day that the fractured tibiae released significantly more prostaglandin E than the tibiae which had been pinned, but not fractured. Similar results were obtained for the release from the muscles surrounding the tibiae. Prostaglandins are important mediators of inflammation as well as potent stimulators of bone resorption. Their increased formation in response to fracture and pinning may stimulate the vascular changes, bone resorption and the proliferation of osteogenic cells observed after trauma to bone.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cited by
Cyclo-Oxygenase 2 Function Is Essential for Bone Fracture Healing
Simon, A. M., Manigrasso, M. B., & O'Connor, J. P. (2002) · Journal of Bone and Mineral Research · doi:10.1359/jbmr.2002.17.6.963 · Cited by 530
Effects of Perioperative Antiinflammatory and Immunomodulating Therapy on Surgical Wound Healing
Busti, A. J., Hooper, J. S., Amaya, C. J., & Kazi, S. (2005) · Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy · doi:10.1592/phco.2005.25.11.1566 · Cited by 221
Pharmacological agents and impairment of fracture healing: What is the evidence?
Pountos, I., Georgouli, T., Blokhuis, T. J., Pape, H. C., & Giannoudis, P. V. (2008) · Injury · doi:10.1016/j.injury.2007.10.035 · Cited by 168
Harder, A. T., & An, Y. H. (2003) · The Journal of Clinical Pharmacology · doi:10.1177/0091270003256061 · Cited by 155
Effects of cyclooxygenase inhibition on bone, tendon, and ligament healing
Radi, Z. A., & Khan, N. K. (2005) · Inflammation Research · doi:10.1007/s00011-005-1367-4 · Cited by 113
Metadata
- Authors
- Dekel, S., Lenthall, G., & Francis, M.
- Venue
- The Journal of Bone and Joint Surgery. British volume
- Published
- 1981-05
- Volume
- 63-B
- Issue
- 2
- Pages
- 185-189
- ISSN
- 0301-620X (ISSN-L)
- 2044-5377
- OpenAlex
- W2288661744
- Cited by
- 176
- References
- 0
- FWCI
- 3.42
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Release of prostaglandins from bone and muscle after tibial fracture. An experimental study in rabbits. https://app.cochat.ai/papers/10.1302/0301-620x.63b2.7217139
- The paper
- Dekel, S., Lenthall, G., & Francis, M. (1981). Release of prostaglandins from bone and muscle after tibial fracture. An experimental study in rabbits. The Journal of Bone and Joint Surgery. British volume. https://doi.org/10.1302/0301-620x.63b2.7217139
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
