Assessment of Data Quality Variability across Two EHR Systems through a Case Study of Post-Surgical Complications
Open accessAbstract
Translation of predictive modeling algorithms into routine clinical care workflows faces challenges in the form of varying data quality-related issues caused by the heterogeneity of electronic health record (EHR) systems. To better understand these issues, we retrospectively assessed and compared the variability of data produced from two different EHR systems. We considered three dimensions of data quality in the context of EHR-based predictive modeling for three distinct translational stages: model development (data completeness), model deployment (data variability), and model implementation (data timeliness). The case study was conducted based on predicting post-surgical complications using both structured and unstructured data. Our study discovered a consistent level of data completeness, a high syntactic, and moderate-high semantic variability across two EHR systems, for which the quality of data is context-specific and closely related to the documentation workflow and the functionality of individual EHR systems.
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Anemia is named differently across EHR systems; one might call it post-hemorrhagic anemia, while another refers to it as blood loss anemia.
“For example, anemia is named differently across systems; one might call it “post-hemorrhagic anemia”, while another refers to it as “blood loss anemia”.”
From Toward Safer Diagnoses: A SEIPS-Based Narrative Review of Diagnostic Errors (2026) · cites this paper as [170]
The Results (page unavailable) report that anemia expressions vary between Epic and Centricity. But the paper gives “Anemia Posthemorrhagic Acute (Blood Loss Anemia)” as one expression; it does not say one system uses “post-hemorrhagic anemia” while the other uses “blood loss anemia.” (LLM, conf=0.86)
Experimental — accuracy not yet measuredSuch inconsistencies result in patient record discrepancies and complicate clinician interpretations.
“Such inconsistencies result in patient record discrepancies and complicate clinician interpretations [170].”
From Toward Safer Diagnoses: A SEIPS-Based Narrative Review of Diagnostic Errors (2026) · cites this paper as [170]
The Abstract and Discussion report differences in data completeness, documentation, and syntactic and semantic content across two EHR systems, supporting the point about inconsistent patient-record data. They do not report that these differences complicated clinicians’ interpretations; the stated consequences concern predictive models and data quality. (LLM, conf=0.82)
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Cites
Mann, C. J. (2003) · Emergency Medicine Journal · doi:10.1136/emj.20.1.54 · Cited by 1,558 · see citing works
Weiskopf, N. G., & Weng, C. (2013) · Journal of the American Medical Informatics Association · doi:10.1136/amiajnl-2011-000681 · Cited by 1,216 · see citing works
Wong, A., Otles, E., Donnelly, J. P., Krumm, A., McCullough, J., DeTroyer-Cooley, O., Pestrue, J., Phillips, M., Konye, J., Penoza, C., et al. (2021) · JAMA Internal Medicine · doi:10.1001/jamainternmed.2021.2626 · Cited by 995 · see citing works
Cohen, G. R., Friedman, C. P., Ryan, A. M., Richardson, C. R., & Adler-Milstein, J. (2019) · Journal of General Internal Medicine · doi:10.1007/s11606-019-05025-3 · Cited by 117 · see citing works
Flagged first, then by citations
Research works printed but not linked: 29
- [1]1. Gelijns AC, Gabriel SE. Looking beyond translation-integrating clinical research with medical practice. N Engl J Med. 2012;366(18):1659-61.
- [2]2. Arnold Milstein M. Code red and blue--safely limiting health care's GDP footprint. The New England journal of medicine. 2013;368(1):1.
- [3]3. Bennett CC, Doub TW, Selove R. EHRs connect research and practice: Where predictive modeling, artificial intelligence, and clinical decision support intersect. Health Policy and Technology. 2012;1(2):105-14.
- [4]4. Wu G, Yang P, Xie Y, Woodruff HC, Rao X, Guiot J, et al. Development of a clinical decision support system for severity risk prediction and triage of COVID-19 patients at hospital admission: an international multicentre study. European Respiratory Journal. 2020;56(2).
- [5]5. Pencina MJ, Peterson ED. Moving from clinical trials to precision medicine: the role for predictive modeling. Jama. 2016;315(16):1713-4.
- [6]6. Yeh RW, Secemsky EA, Kereiakes DJ, Normand S-LT, Gershlick AH, Cohen DJ, et al. Development and validation of a prediction rule for benefit and harm of dual antiplatelet therapy beyond 1 year after percutaneous coronary intervention. Jama. 2016;315(16):1735-49.
- [7]7. Dikilitas O, Schaid DJ, Kosel ML, Carroll RJ, Chute CG, Denny JA, et al. Predictive utility of polygenic risk scores for coronary heart disease in three major racial and ethnic groups. The American Journal of Human Genetics. 2020;106(5):707-16.
- [8]8. Oliwa T, Furner B, Schmitt J, Schneider J, Ridgway JP. Development of a predictive model for retention in HIV care using natural language processing of clinical notes. Journal of the American Medical Informatics Association. 2021;28(1):104-12.
- [10]10. Paxton C, Niculescu-Mizil A, Saria S, editors. Developing predictive models using electronic medical records: challenges and pitfalls. AMIA Annual Symposium Proceedings; 2013: American Medical Informatics Association.
- [13]13. Botsis T, Hartvigsen G, Chen F, Weng C. Secondary use of EHR: data quality issues and informatics opportunities. Summit on Translational Bioinformatics. 2010;2010:1.
- [14]14. Fu S, Leung LY, Raulli A-O, Kallmes DF, Kinsman KA, Nelson KB, et al. Assessment of the impact of EHR heterogeneity for clinical research through a case study of silent brain infarction. BMC medical informatics and decision making. 2020;20(1):1-12.
- [15]15. Sohn S, Wang Y, Wi C-I, Krusemark EA, Ryu E, Ali MH, et al. Clinical documentation variations and NLP system portability: a case study in asthma birth cohorts across institutions. Journal of the American Medical Informatics Association. 2018;25(3):353-9.
- [17]17. Zhang R, Pakhomov S, McInnes BT, Melton GB, editors. Evaluating measures of redundancy in clinical texts. AMIA annual symposium proceedings; 2011: American Medical Informatics Association.
- [18]18. Thaker VV, Lee F, Bottino CJ, Perry CL, Holm IA, Hirschhorn JN, et al. Impact of an electronic template on documentation of obesity in a primary care clinic. Clinical pediatrics. 2016;55(12):1152-9.
- [20]20. Cima R, Dankbar E, Lovely J, Pendlimari R, Aronhalt K, Nehring S, et al. Colorectal surgery surgical site infection reduction program: a national surgical quality improvement program-driven multidisciplinary singleinstitution experience. Journal of the American College of Surgeons. 2013;216(1):23-33.
- [21]21. Ko CY, Hall BL, Hart AJ, Cohen ME, Hoyt DB. The American college of surgeons national surgical quality improvement program: achieving better and safer surgery. The Joint Commission Journal on Quality and Patient Safety. 2015;41(5):199-AP1.
- [22]22. Ingraham AM, Richards KE, Hall BL, Ko CY. Quality improvement in surgery: the American College of Surgeons national surgical quality improvement program approach. Advances in surgery. 2010;44(1):251-67.
- [23]23. Wen A, Fu S, Moon S, El Wazir M, Rosenbaum A, Kaggal VC, et al. Desiderata for delivering NLP to accelerate healthcare AI advancement and a Mayo Clinic NLP-as-a-service implementation. NPJ digital medicine. 2019;2(1):1-7.
- [24]24. Liu H, Bielinski SJ, Sohn S, Murphy S, Wagholikar KB, Jonnalagadda SR, et al. An information extraction framework for cohort identification using electronic health records. AMIA Summits on Translational Science Proceedings. 2013;2013:149.
- [25]25. Weiskopf NG, Hripcsak G, Swaminathan S, Weng C. Defining and measuring completeness of electronic health records for secondary use. Journal of biomedical informatics. 2013;46(5):830-6.
- [27]27. Elkin PL, Froehling D, Bauer BA, Wahner-Roedler D, Rosenbloom S, Bailey K, et al., editors. Aequus communis sententia: defining levels of interoperability. Medinfo 2007: Proceedings of the 12th World Congress on Health (Medical) Informatics; Building Sustainable Health Systems; 2007: IOS Press.
- [28]28. David L. Master data management. Morgan Kaufmann Press: San Francisco, CA, USA; 2009.
- [29]29. Dolin RH, Alschuler L, Beebe C, Biron PV, Boyer SL, Essin D, et al. The HL7 clinical document architecture. Journal of the American Medical Informatics Association. 2001;8(6):552-69.
- [30]30. Sohn S, Larson DW, Habermann EB, Naessens JM, Alabbad JY, Liu H. Detection of clinically important colorectal surgical site infection using Bayesian network. Journal of Surgical Research. 2017;209:168-73.
- [32]32. Wang Y, Afzal N, Fu S, Wang L, Shen F, Rastegar-Mojarad M, et al. MedSTS: a resource for clinical semantic textual similarity. Language Resources and Evaluation. 2020;54(1):57-72.
- [33]33. Singhal A. Modern information retrieval: A brief overview. IEEE Data Eng Bull. 2001;24(4):35-43.
- [34]34. Chen D, Afzal N, Sohn S, Habermann EB, Naessens JM, Larson DW, et al. Postoperative bleeding risk prediction for patients undergoing colorectal surgery. Surgery. 2018;164(6):1209-16.
- [35]35. Sambasivan N, Kapania S, Highfill H, Akrong D, Paritosh P, Aroyo LM, editors. 'Everyone wants to do the model work, not the data work': Data Cascades in High-Stakes AI. proceedings of the 2021 CHI Conference on Human Factors in Computing Systems; 2021.
- [36]36. Leung LY, Fu S, Luetmer PH, Kallmes DF, Madan N, Weinstein G, et al. Agreement between neuroimages and reports for natural language processing-based detection of silent brain infarcts and white matter disease. BMC neurology. 2021;21(1):1-5.
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Electronic Health Record Data Quality Assessment and Tools: A Systematic Review
Lewis, A. E., Weiskopf, N., Abrams, Z. B., Foraker, R., Lai, A. M., Payne, P. R. O., & Gupta, A. (2023) · Journal of the American Medical Informatics Association · doi:10.1093/jamia/ocad120 · Cited by 171 · see citing works
Fu, S., Vassilaki, M., Ibrahim, O. A., Petersen, R. C., Pagali, S., St Sauver, J., Moon, S., Wang, L., Fan, J. W., Liu, H., et al. (2022) · Frontiers in Digital Health · doi:10.3389/fdgth.2022.958539 · Cited by 15 · see citing works
Self-citationToward Safer Diagnoses: A SEIPS-Based Narrative Review of Diagnostic Errors
Yen, C., Epling, J. W., Rockwell, M., & Vaughn-Cooke, M. (2026) · Diagnostics · doi:10.3390/diagnostics16020347 · Cited by 6 · see citing works
- Authors
- Fu, S., Wen, A., Schaeferle, G. M., Wilson, P., Demuth, G. O., Ruan, X., Liu, S., Storlie, C. B., & Liu, H.
- Affiliations
- Mayo Clinic (US)
- ORCID
- Venue
- Unpublished
- Publisher
- Unpublished
- Published
- 2022
- Volume
- 2022
- Pages
- 196-205
- PMC
- PMC9285181
- OpenAlex
- W4286377178
- Cited by
- 16
- References
- 4
- Citations by year
- 2025: 5 · 2024: 3 · 2023: 5 · 2022: 2
- FWCI
- 2.60
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Institutes of Health (U01TR002062)
- National Institute of Biomedical Imaging and Bioengineering (R01EB019403)
- Topics
- Health Sciences › Health Professions › Health Information Management › Electronic Health Records Systems
- Physical Sciences › Computer Science › Artificial Intelligence › Machine Learning in Healthcare
- Health Sciences › Health Professions › Health Information Management › Medical Coding and Health Information
- Keywords
- data quality, postoperative complications, predictive modeling, structured and unstructured data, data completeness, data timeliness, semantic variation, syntactic variation, model implementation
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