Bench to Bedside: Mapping the Moral Terrain of Clinical Research
Abstract
Medical research is widely thought to have a fundamentally therapeutic orientation, in spite of the fact that clinical research is thought to be ethically distinct from medical care. We need an entirely new conception of clinical research ethics - one that looks to science instead of the doctor-patient relationship.
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In contrast to clinical care, the goal of research is not to optimize individual preferences, but rather to generate socially valuable scientific knowledge.
“In contrast to clinical care, the goal of research is not to optimize individual preferences, but rather to generate socially valuable scientific knowledge (72).”
From Lessons from HeLa Cells: The Ethics and Policy of Biospecimens (2016) · cites this paper as [72]
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Richardson, H. S., & Belsky, L. (2004) · The Hastings Center Report · doi:10.2307/3528248 · Cited by 217 · see citing works
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Lessons from HeLa Cells: The Ethics and Policy of Biospecimens
Beskow, L. M. (2016) · Annual Review of Genomics and Human Genetics · doi:10.1146/annurev-genom-083115-022536 · Cited by 146 · see citing works
“In contrast to clinical care, the goal of research is not to optimize individual preferences, but rather to generate socially valuable scientific knowledge (72).”
BackgroundThe clinical investigator-subject relationship: a contextual approach
Resnik, D. B. (2009) · Philosophy, Ethics, and Humanities in Medicine · doi:10.1186/1747-5341-4-16 · Cited by 32 · see citing works
- Authors
- Joffe, S., & Miller, F. G.
- Venue
- Hastings Center Report
- Publisher
- Project MUSE
- Published
- 2008
- Volume
- 38
- Issue
- 2
- Pages
- 30-42
- ISSN
- 0093-0334 (ISSN-L)
- 1552-146X
- OpenAlex
- W2032512219
- Cited by
- 122
- References
- 1
- Citations by year
- 2025: 4 · 2024: 4 · 2023: 4 · 2022: 4 · 2021: 8 · 2020: 9 · 2019: 7 · 2018: 3 · 2017: 7 · 2016: 12 · 2015: 10 · 2014: 7 · 2013: 5 · 2012: 11
- FWCI
- 8.94
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- The Hastings Center Report (publishedVersion)
- PubMed (publishedVersion)
- Project Muse (Johns Hopkins University) (submittedVersion)
- DigitalGeorgetown (Georgetown University Library) (submittedVersion)
- Funders
- University of Michigan
- National Institutes of Health (5k01ca096872-02)
- National Cancer Institute (K01-CA096872)
- Topics
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Ethics in Clinical Research
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Ethics and bioethics in healthcare
- Health Sciences › Medicine › Physiology › Biomedical Ethics and Regulation
- Keywords
- clinical research ethics, research ethics
- MeSH terms
- Animals, Clinical Trials as Topic, Ethics, Medical, Humans, Physician-Patient Relations, Physicians, Research Personnel, Patient Selection, Ethics, Clinical, Moral Obligations, Ethics, Research, Nontherapeutic Human Experimentation, Biomedical Research, Researcher-Subject Relations, Therapeutic Human Experimentation
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